Product image of Insuman Infusat (Insulin Human) supplied by GNH India

Insuman Infusat

Active Ingredient:
Insulin Human
Origin:
EU

Insuman Infusat (Insulin Human)

Insulin Human, the active ingredient in Insuman Infusat, is an insulin presented as a sterile solution for subcutaneous use. It lowers blood glucose levels and is used in the management of diabetes mellitus in both type 1 and type 2 patients.

GNH India supplies Insuman Infusat as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide, ensuring quality and regulatory compliance across global markets. The company adheres to stringent quality standards and provides reliable logistics for timely delivery.

Manufacturer / TM Owner

Sanofi-Aventis Deutschland Gmbh

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Indications & Clinical Uses

Insuman Infusat (insulin human) is used in the insulin pathway to control hyperglycemia in diabetes mellitus.

  • Type 1 diabetes mellitus: provides basal and prandial insulin to achieve glycemic control.
  • Type 2 diabetes mellitus: supplements endogenous insulin to improve blood glucose regulation.
  • Diabetic ketoacidosis: used as part of emergency insulin therapy to reduce plasma glucose levels.

How It Works

  • Insulin Human binds to insulin receptors on cell membranes, activating the receptor's intrinsic tyrosine kinase activity. This triggers a cascade that promotes translocation of GLUT‑4 transporters to the cell surface, enhancing glucose uptake in muscle and adipose tissue while suppressing hepatic glucose production, thereby lowering circulating blood glucose.

Side Effects

Common Side Effects

  • Hypoglycemia (low blood sugar).
  • Injection‑site pain, redness or swelling.
  • Weight gain.
  • Lipodystrophy at injection sites.
  • Peripheral edema.

Serious or Rare Side Effects

  • Severe allergic reaction (anaphylaxis).
  • Hypokalemia.
  • Acute insulin overdose leading to seizures or coma.
  • Stevens‑Johnson syndrome (very rare).

Precautions & Warnings

Before using Insuman Infusat, consider the following precautions:

  • Dose titration: adjust based on self‑monitoring of blood glucose.
  • Hypoglycemia risk: educate patients on recognizing and treating low glucose episodes.
  • Renal impairment: may require lower doses and close monitoring.
  • Hepatic impairment: monitor glucose closely and adjust therapy as needed.
  • Pregnancy and lactation: use only if benefits outweigh potential risks.
  • Store at 2-8°C: keep refrigerated, protect from light, do not freeze or shake.

Avoid Interactions

Insuman Infusat may interact with other medicines as follows:

Major Interactions (Avoid)

  • Concurrent use of other insulin products: risk of severe hypoglycemia.
  • Beta‑adrenergic blockers: may mask hypoglycemia symptoms.

Moderate Interactions (Monitor Closely)

  • Sulfonylureas or meglitinides: additive glucose‑lowering effect; monitor for hypoglycemia.
  • ACE inhibitors or ARBs: may enhance insulin sensitivity; monitor glucose levels.
  • Thiazide diuretics: may increase blood glucose; adjust therapy as needed.
  • Oral corticosteroids: may raise glucose; consider dose adjustments.

Frequently Asked Questions

Insuman Infusat contains insulin human and is used to lower elevated blood glucose levels in patients with diabetes mellitus, including both type 1 and type 2 diabetes. It helps achieve glycemic control when endogenous insulin production is insufficient or when additional insulin is required.

Insulin human binds to insulin receptors on cell surfaces, activating intracellular pathways that promote the movement of glucose transporters to the cell membrane. This increases glucose uptake into muscle and fat cells and suppresses glucose production by the liver, resulting in reduced blood glucose concentrations.

The dose of Insuman Infusat is individualized. A qualified prescriber determines the appropriate amount based on the patient’s blood glucose readings, body weight, diet, activity level, and overall treatment plan. Patients should follow the prescribing clinician’s instructions and adjust only under medical guidance.

Insulin human is classified as a pregnancy category that may be used when the potential benefit justifies the potential risk to the fetus. It is generally considered safe for use in pregnancy and lactation because insulin does not cross the placenta in significant amounts, but treatment decisions should be made by a healthcare professional.

To request Insuman Infusat, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including cold‑chain handling if needed), and import documentation.

Insuman Infusat contains recombinant human insulin, which has a molecular structure identical to endogenous insulin. Compared with insulin analogues, it may have a shorter duration of action and a different onset profile. Choice of product depends on clinical goals, dosing convenience, and individual patient response as assessed by the prescribing clinician.

Insuman Infusat should be stored in a refrigerator at 2‑8 °C, protected from light, and kept in its original container. Do not freeze or shake the vial. Once in use, the product may be kept at controlled room temperature (up to 25 °C) for a limited period, as indicated on the label.

Insuman Infusat is administered by subcutaneous injection into the abdomen, thigh, or upper arm. The injection technique, site rotation, and dosing schedule should follow the prescriber’s instructions and standard insulin administration guidelines to ensure optimal absorption and minimize injection‑site complications.

The most serious risks include severe hypoglycemia, which can cause loss of consciousness or seizures, and allergic reactions ranging from local irritation to anaphylaxis. Patients should be educated on recognizing early signs of low blood sugar and on steps to take in case of a suspected allergic response.

Insuman Infusat should be avoided in individuals with a known hypersensitivity to insulin human or any excipients in the formulation. It is also contraindicated in patients experiencing hypoglycemia until glucose levels are corrected. Clinicians must assess each patient’s medical history before initiating therapy.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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