Product image of Intesticortproct (Budesonide) supplied by GNH India

Intesticortproct

Active Ingredient:
Budesonide
Origin:
EU

Intesticortproct (Budesonide)

Budesonide, the active ingredient in Intesticortproct, is a corticosteroid presented as a rectal formulation for local use. It is employed to reduce inflammation in the lower gastrointestinal tract, particularly in ulcerative colitis and proctitis patients. GNH India supplies Intesticortproct as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Dr. Falk Pharma G.M.B.H.

1
Pack/s
This product is added to your enquiry list

Request a Quote

Please fill out the form below and our team will get back to you shortly with pricing and further information.

A minimum order value applies. Our team will confirm the exact amount or quantity after reviewing your requirements.

Indications & Clinical Uses

Intesticortproct contains budesonide, a corticosteroid that acts on inflammatory bowel disease pathways.

  • Ulcerative colitis: reduces mucosal inflammation and promotes remission in the colon.
  • Proctitis: alleviates rectal inflammation and associated symptoms.
  • Inflammatory bowel disease (maintenance): helps maintain remission when used as directed.

How It Works

  • Budesonide binds to intracellular glucocorticoid receptors, forming a complex that translocates to the nucleus and modulates gene transcription. This action suppresses pro‑inflammatory cytokine production, inhibits leukocyte migration, and stabilises lysosomal membranes, resulting in a potent local anti‑inflammatory effect within the rectal mucosa.

Side Effects

Intesticortproct may cause a range of adverse reactions.

Common Side Effects

  • Rectal irritation or burning sensation
  • Itching or mild pruritus at the application site
  • Discharge or mucus leakage
  • Headache
  • Nausea
  • Mild abdominal cramping

Serious or Rare Side Effects

  • Adrenal suppression with prolonged use
  • Severe infection or sepsis
  • Allergic reaction (rash, swelling, anaphylaxis)
  • Colonic perforation
  • Significant gastrointestinal bleeding
  • Systemic corticosteroid effects (e.g., hyperglycaemia)

Precautions & Warnings

Before prescribing Intesticortproct, clinicians should consider several safety measures.

  • Assess disease severity: confirm that rectal therapy is appropriate for the extent of inflammation.
  • Monitor for infection: avoid use in patients with active systemic infections.
  • Avoid systemic corticosteroid overuse: limit duration to reduce adrenal suppression risk.
  • Use with caution in pregnancy: safety data are limited; discuss risks with the patient.
  • Use with caution in immunocompromised individuals: increased infection risk.
  • Store at room temperature: keep in the original packaging, protect from moisture and direct sunlight.

Avoid Interactions

Budesonide may interact with other medicines, requiring careful management.

Major Interactions (Avoid)

  • Systemic corticosteroids: additive glucocorticoid effects may increase adrenal suppression.
  • Strong CYP3A4 inhibitors (e.g., ketoconazole, itraconazole): can raise budesonide plasma levels.
  • Antifungal agents (e.g., fluconazole): may enhance systemic exposure.

Moderate Interactions (Monitor Closely)

  • NSAIDs: increased risk of gastrointestinal irritation or ulceration.
  • Anticoagulants (e.g., warfarin): potential for altered bleeding risk.
  • Live vaccines: reduced vaccine efficacy and possible infection.

Frequently Asked Questions

Intesticortproct is a rectally administered budesonide product indicated for the treatment of ulcerative colitis and proctitis. It works locally to reduce inflammation in the lower gastrointestinal tract, helping to control symptoms such as bleeding, urgency, and abdominal discomfort.

Budesonide is a glucocorticoid receptor agonist. After binding to intracellular receptors, it modulates gene transcription, suppressing pro‑inflammatory cytokines, inhibiting leukocyte migration, and stabilising cell membranes. This results in a potent anti‑inflammatory effect at the site of application.

The specific dose and treatment duration are determined by the prescribing clinician based on disease severity, patient response, and safety considerations. Healthcare professionals tailor the regimen to each individual, and patients should follow the prescriber’s instructions precisely.

Safety data for budesonide rectal use in pregnancy and lactation are limited. The product should only be used if the potential benefit justifies any potential risk to the fetus or infant. Patients should discuss their situation with a qualified healthcare provider before starting therapy.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including any cold‑chain requirements), and necessary import documentation.

Intesticortproct delivers budesonide, a high‑potency corticosteroid with strong local anti‑inflammatory activity and minimal systemic absorption. Compared with mesalamine enemas, budesonide often provides faster symptom relief but may carry a higher risk of corticosteroid‑related side effects. Choice of therapy depends on disease severity, patient tolerance, and physician preference.

Store the product at room temperature, below 25 °C, in its original packaging. Protect it from moisture, direct sunlight, and extreme temperatures. Do not refrigerate or freeze the product, and keep it out of reach of children.

Intesticortproct is administered rectally. The prescribed dose is inserted into the rectum using the supplied applicator or a clean fingertip, following the instructions provided by the healthcare professional. Patients should remain lying down for a few minutes after insertion to ensure optimal absorption.

Serious risks include adrenal suppression with prolonged use, severe infections due to immunosuppression, allergic reactions such as rash or anaphylaxis, and rare events like colonic perforation or significant gastrointestinal bleeding. Patients should seek immediate medical attention if they experience signs of infection, severe abdominal pain, or allergic symptoms.

Intesticortproct is contraindicated in individuals with known hypersensitivity to budesonide or any excipients, those with active systemic infections, and patients with severe uncontrolled diabetes or uncontrolled hypertension where systemic corticosteroid effects could be harmful. Clinicians should evaluate each patient’s medical history before prescribing.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

Disclaimer

At GNH India, we aim to provide information that is expert-reviewed, accurate, and reliable. However, all content on this platform is intended for general informational purposes only and does not constitute professional medical advice, diagnosis, or treatment. While efforts are made to maintain accuracy and currency, the information may contain errors, omissions, or may not reflect the latest developments. Always consult a qualified healthcare professional regarding any medical concerns.

All product names, brand names, trademarks and registered trademarks displayed on this website are the property of their respective owners. This website and its operator are not affiliated with, endorsed by, or authorized by any such trade mark owners unless expressly stated. Any reference to product names or trademarks is made solely for descriptive and informational purposes. No commercial relationship, sponsorship, approval, or association with any trademark owner should be inferred. Information provided herein does not constitute promotion, advertising, or an offer for sale of any medicinal product and is intended solely for general informational purposes.

All trademarks and brand names displayed on this website are used strictly in accordance with the provisions of the Trade Marks Act, 1999, specifically Sections 30 and 30(1) governing fair use. Trademark ownership has been accurately attributed under the "Manufacturer/ TM Owner" section in compliance with statutory requirements.

Ordering Process

Simple, Secure, and Seamless

Learn how our streamlined ordering process guarantees fast, compliant, and reliable access to essential medicines worldwide.

Quote request form

01

Submit Quote Request Form

Tell us what medications you need by filling out our simple form and uploading a valid document.

Price estimate review

02

We Review & Send Estimate

Our licensed pharmacists will verify your details and provide you with a detailed cost estimate.

Secure payment

03

Confirm & Make Payment

Discuss any queries, approve the estimate, and complete your payment.

Worldwide delivery

04

Get Delivered

Your medicines, safely packed and delivered to your door or nearest airport — hassle-free.

Quality You Can Trust

Our internationally recognized certifications underscore our commitment to safety, quality, and excellence.