Product image of Intrafusin (Valine, Acetylcysteine, Alanine, Arginine, Histidine, Isoleucine, Leucine, Methionine, Phenylalanine) supplied by GNH India

Intrafusin

Active Ingredient:
Valine, Acetylcysteine, Alanine, Arginine, Histidine, Isoleucine, Leucine, Methionine, Phenylalanine
Origin:
EU

Intrafusin (Valine, Acetylcysteine, Alanine, Arginine, Histidine, Isoleucine, Leucine, Methionine, Phenylalanine)

Valine, Acetylcysteine, Alanine, Arginine, Histidine, Isoleucine, Leucine, Methionine, Phenylalanine, the active ingredient in Intrafusin, is a nutrition supplement presented as a solution for injection for intravenous use. It provides essential and non‑essential amino acids to support protein synthesis and metabolic processes in patients requiring parenteral nutrition.

GNH India supplies Intrafusin as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, transplant centres, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Baxter Deutschland Gmbh

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Indications & Clinical Uses

  • Intrafusin is used in parenteral nutrition to supply amino acids for patients unable to receive oral intake.
  • Severe malnutrition: supports protein synthesis and nitrogen balance.
  • Post‑operative recovery: provides essential amino acids for tissue repair.
  • Critical illness (e.g., sepsis, trauma): maintains metabolic needs when enteral feeding is contraindicated.

How It Works

  • Intrafusin delivers a balanced mixture of essential and non‑essential amino acids directly into the bloodstream, bypassing gastrointestinal absorption. The amino acids become substrates for cellular protein synthesis, gluconeogenesis, and other metabolic pathways, helping to restore nitrogen balance, support tissue repair, and sustain energy production in patients receiving parenteral nutrition.

Side Effects

Intrafusin may be associated with infusion‑related and metabolic reactions.

Common Side Effects

  • Infusion site erythema: mild redness at the catheter site.
  • Mild nausea: transient discomfort during or after infusion.
  • Transient hyperglycemia: temporary rise in blood glucose levels.
  • Electrolyte shift (e.g., mild hypokalemia): small changes in serum potassium.

Serious or Rare Side Effects

  • Anaphylactic reaction: severe allergic response requiring immediate medical attention.
  • Severe hyperosmolarity: marked increase in plasma osmolality.
  • Metabolic acidosis: significant drop in blood pH.
  • Thrombophlebitis: inflammation of a vein with clot formation.

Precautions & Warnings

  • When using Intrafusin, clinicians should consider several safety aspects.
  • Renal impairment: monitor serum creatinine and adjust infusion rate.
  • Liver dysfunction: assess amino acid metabolism and liver function tests.
  • Electrolyte disorders: check serum electrolytes before and during therapy.
  • Hyperglycemia risk: monitor blood glucose in diabetic patients.
  • Allergy to any component: discontinue if hypersensitivity occurs.
  • Store at 2-8°C: keep refrigerated, protect from light, do not freeze or shake.

Avoid Interactions

Intrafusin can interact with other intravenous agents and systemic therapies.

Major Interactions (Avoid)

  • Concurrent high‑dose potassium supplements: may cause hyperkalemia.
  • Incompatible IV solutions (e.g., calcium chloride): can precipitate.

Moderate Interactions (Monitor Closely)

  • Insulin therapy: may require dose adjustment due to glucose load.
  • Diuretics: monitor electrolyte balance.
  • Other parenteral nutrition admixtures: assess total amino acid and nitrogen load.

Frequently Asked Questions

Intrafusin is an intravenous amino acid solution used as part of parenteral nutrition to provide essential and non‑essential amino acids for patients who cannot receive adequate nutrition by mouth or enteral feeding.

The blend supplies the body with building blocks for protein synthesis, supports nitrogen balance, and fuels metabolic pathways such as gluconeogenesis, helping to maintain tissue integrity and energy production in critically ill or malnourished patients.

The prescribed dose of Intrafusin is determined by the treating physician based on the patient’s weight, clinical condition, and nutritional requirements. Dosage is individualized and administered under medical supervision.

Safety data for Intrafusin in pregnancy and lactation are limited. Use should be considered only if the potential benefit justifies any potential risk to the fetus or infant, and it must be prescribed by a qualified healthcare professional.

To order Intrafusin, submit an enquiry on the product page at gnhindia.com with the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including cold‑chain where needed) and import documentation.

Intrafusin offers a comprehensive profile of both essential and non‑essential amino acids in a single sterile solution, matching or exceeding the amino acid composition of many standard parenteral nutrition admixtures while meeting EU quality standards.

Intrafusin should be stored at 2‑8 °C, protected from light, and must not be frozen or shaken. Keep the vial in its original packaging until use to maintain sterility and stability.

Intrafusin is administered intravenously as a sterile solution for injection. It is typically infused over a prescribed period using an infusion pump or controlled drip, following aseptic technique and institutional protocols.

Serious risks include anaphylactic reactions, severe hyperosmolarity, metabolic acidosis, and thrombophlebitis. Patients should be monitored closely for signs of allergy, electrolyte disturbances, and changes in metabolic parameters during infusion.

Intrafusin should be avoided in patients with known hypersensitivity to any of its amino acid components, severe hepatic or renal failure without appropriate monitoring, and in those receiving incompatible intravenous solutions that may precipitate.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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