Intrarosa (Prasterone)

Prasterone is locally converted within the vaginal mucosa into estrogen and androgen metabolites. These hormones bind to their receptors, stimulating epithelial cell growth, increasing glycogen storage, and enhancing blood flow, which together improve tissue thickness, lubrication, and overall vaginal comfort.

The dosage of Intrarosa is determined by the prescribing healthcare professional based on individual patient needs. Typically, a single vaginal insert is administered according to the clinician’s instructions, and the treatment schedule may be adjusted during follow‑up visits.

Safety of Intrarosa in pregnancy has not been established, and it is generally avoided in pregnant women. Information on use while breastfeeding is limited; therefore, the potential risks and benefits should be carefully evaluated by a healthcare provider before use.

To order Intrarosa, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

The main alternative to Intrarosa is topical estrogen therapy, which delivers estrogen systemically through the vaginal mucosa. Intrarosa provides both estrogenic and androgenic activity locally, potentially offering broader tissue benefits. Choice of therapy depends on patient preference, tolerance, and clinician assessment.

Intrarosa should be stored at room temperature, away from excessive heat and moisture. Keep the inserts in their original packaging until use, and protect them from direct sunlight. Do not refrigerate or freeze the product unless specifically instructed by the manufacturer.

Intrarosa is a vaginal insert designed for intravaginal placement. The patient inserts the device into the vagina using a clean fingertip or applicator as directed by the prescribing clinician, typically before bedtime to allow optimal absorption.

Serious risks include unexplained vaginal bleeding, endometrial hyperplasia, severe abdominal pain, and allergic reactions such as rash or swelling. Patients should seek immediate medical attention if they experience any of these symptoms while using the product.

Intrarosa is contraindicated in women who are pregnant, have known hypersensitivity to prasterone or any excipients, or have active hormone‑dependent cancers such as breast or endometrial carcinoma. It should also be used with caution in patients with uncontrolled metabolic disorders.