Product image of Inuvair Nexthaler (Formoterol Fumarate Dihydrate, Beclometasone Dipropionate Anhydrous) supplied by GNH India

Inuvair Nexthaler

Active Ingredient:
Formoterol Fumarate Dihydrate, Beclometasone Dipropionate Anhydrous
Origin:
EU

Inuvair Nexthaler (Formoterol Fumarate Dihydrate, Beclometasone Dipropionate Anhydrous)

Beclometasone dipropionate and Formoterol fumarate, the active ingredients in Inuvair Nexthaler, are an inhaled corticosteroid/long‑acting β2‑agonist combination presented as a dry powder inhaler for inhalation use. They work together to reduce airway inflammation and to relax bronchial smooth muscle, providing maintenance therapy for asthma and chronic obstructive pulmonary disease in adult patients.

GNH India supplies Inuvair Nexthaler as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide, ensuring quality and regulatory compliance for global distribution.

Manufacturer / TM Owner

Chiesi Farmaceutici S.P.A.

1
Pack/s
This product is added to your enquiry list

Request a Quote

Please fill out the form below and our team will get back to you shortly with pricing and further information.

A minimum order value applies. Our team will confirm the exact amount or quantity after reviewing your requirements.

Indications & Clinical Uses

  • Inuvair Nexthaler combines an inhaled corticosteroid with a long‑acting β2‑agonist to treat chronic airway diseases.
  • Asthma: maintenance therapy that improves symptom control and reduces exacerbations.
  • COPD: maintenance treatment that enhances lung function and lowers the risk of flare‑ups.
  • Chronic bronchitis (as part of COPD): helps control airway inflammation and provides bronchodilation for better airflow.
  • Severe asthma: adjunct therapy when high‑dose inhaled corticosteroid alone is insufficient.

How It Works

  • Beclometasone dipropionate binds to intracellular glucocorticoid receptors, modulating gene transcription to suppress inflammatory cytokines, reduce eosinophil activity and decrease airway edema. Formoterol fumarate selectively stimulates β2‑adrenergic receptors on bronchial smooth muscle, increasing cyclic AMP levels, which leads to relaxation of the airway smooth muscle and prolonged bronchodilation. The combined actions provide anti‑inflammatory and bronchodilatory effects that together maintain airway patency.

Side Effects

Inhalation of Inuvair Nexthaler may be associated with a range of adverse reactions.

Common Side Effects

  • Throat irritation
  • Hoarseness
  • Oral candidiasis (thrush)
  • Cough

Serious or Rare Side Effects

  • Paradoxical bronchospasm
  • Adrenal suppression
  • Severe allergic reactions (anaphylaxis)

Precautions & Warnings

  • Use of Inuvair Nexthaler requires careful clinical assessment and patient education.
  • Assess infection status: avoid initiating during active respiratory infections.
  • Monitor for oral thrush: rinse mouth after each inhalation.
  • Evaluate cardiovascular health: use with caution in patients with arrhythmias or severe hypertension.
  • Use lowest effective dose: adjust based on clinical response and guideline recommendations.
  • Discontinue gradually: abrupt cessation may lead to loss of asthma control.
  • Store at ambient temperature: keep in original container, protect from moisture and heat.

Avoid Interactions

Inuvair Nexthaler may interact with other medicines; review patient medication lists regularly.

Major Interactions (Avoid)

  • Beta‑blockers: may diminish bronchodilator effect and precipitate bronchospasm.
  • Strong CYP3A4 inhibitors (e.g., ketoconazole, itraconazole): increase systemic exposure to beclometasone.
  • Concomitant use of other inhaled corticosteroids: risk of additive systemic steroid effects.

Moderate Interactions (Monitor Closely)

  • Diuretics (e.g., furosemide): may enhance hypokalaemia risk from β2‑agonist activity.
  • Theophylline: β2‑agonist can increase theophylline plasma levels.
  • Non‑selective NSAIDs: may exacerbate bronchospasm in sensitive individuals.

Frequently Asked Questions

Inuvair Nexthaler is a prescription dry‑powder inhaler that combines beclometasone dipropionate, an inhaled corticosteroid, with formoterol fumarate, a long‑acting β2‑agonist. It is indicated for the maintenance treatment of asthma and chronic obstructive pulmonary disease (COPD) in adult patients, helping to control symptoms and reduce the frequency of exacerbations.

Beclometasone dipropionate binds to glucocorticoid receptors in airway cells, suppressing inflammatory gene expression and reducing airway swelling. Formoterol fumarate activates β2‑adrenergic receptors on bronchial smooth muscle, raising cyclic AMP levels and causing prolonged relaxation of the airways. Together they provide anti‑inflammatory and bronchodilatory effects that maintain airway patency.

The prescribed dose of Inuvair Nexthaler is determined by the treating physician based on the severity of the patient’s asthma or COPD, prior treatment response, and guideline recommendations. Patients should follow the specific dosing instructions provided by their healthcare professional and not adjust the dose without medical advice.

Safety data for Inuvair Nexthaler in pregnancy and lactation are limited. The decision to use the inhaler during pregnancy or while breastfeeding should be made by a healthcare professional after weighing the potential benefits for the mother against any possible risks to the fetus or infant.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India supplies hospitals, pharmacies and procurement teams across international markets. After the enquiry, the sales team will verify trade or institutional credentials, then provide pricing, availability, shipping details (including any cold‑chain requirements) and the necessary import documentation.

Inuvair Nexthaler delivers a fixed‑dose combination of an inhaled corticosteroid and a long‑acting β2‑agonist, similar to other combination inhalers such as budesonide/formoterol or fluticasone/salmeterol. Its dry‑powder formulation may offer convenient dosing without propellants, and the specific pharmacokinetic profile of beclometasone and formoterol provides effective anti‑inflammatory and bronchodilator action comparable to alternative products.

Inuvair Nexthaler should be stored at ambient temperature, below 25 °C, in its original packaging. Keep the device away from moisture, direct sunlight and heat sources. Do not expose the inhaler to freezing temperatures, and ensure the mouthpiece remains clean and dry between uses.

The inhaler is a dry‑powder device. The patient should open the mouthpiece, exhale fully away from the inhaler, place the mouthpiece between the lips, and inhale sharply and deeply to ensure the powder is drawn into the lungs. After inhalation, the patient should hold their breath for about 10 seconds, then exhale slowly. The device should be cleaned as instructed in the patient information leaflet.

Serious adverse reactions, although rare, can include paradoxical bronchospasm, adrenal suppression leading to systemic steroid effects, and severe allergic reactions such as anaphylaxis. Patients should seek immediate medical attention if they experience sudden worsening of breathing, signs of infection, unusual fatigue, or any symptoms suggestive of an allergic response.

Inuvair Nexthaler is contraindicated in patients with known hypersensitivity to beclometasone dipropionate, formoterol fumarate, or any component of the inhaler. It should also be avoided in individuals who have experienced a severe allergic reaction to other inhaled corticosteroid/long‑acting β2‑agonist combinations. Patients with uncontrolled cardiovascular disease should use the product only under close medical supervision.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

Disclaimer

At GNH India, we aim to provide information that is expert-reviewed, accurate, and reliable. However, all content on this platform is intended for general informational purposes only and does not constitute professional medical advice, diagnosis, or treatment. While efforts are made to maintain accuracy and currency, the information may contain errors, omissions, or may not reflect the latest developments. Always consult a qualified healthcare professional regarding any medical concerns.

All product names, brand names, trademarks and registered trademarks displayed on this website are the property of their respective owners. This website and its operator are not affiliated with, endorsed by, or authorized by any such trade mark owners unless expressly stated. Any reference to product names or trademarks is made solely for descriptive and informational purposes. No commercial relationship, sponsorship, approval, or association with any trademark owner should be inferred. Information provided herein does not constitute promotion, advertising, or an offer for sale of any medicinal product and is intended solely for general informational purposes.

All trademarks and brand names displayed on this website are used strictly in accordance with the provisions of the Trade Marks Act, 1999, specifically Sections 30 and 30(1) governing fair use. Trademark ownership has been accurately attributed under the "Manufacturer/ TM Owner" section in compliance with statutory requirements.

Ordering Process

Simple, Secure, and Seamless

Learn how our streamlined ordering process guarantees fast, compliant, and reliable access to essential medicines worldwide.

Quote request form

01

Submit Quote Request Form

Tell us what medications you need by filling out our simple form and uploading a valid document.

Price estimate review

02

We Review & Send Estimate

Our licensed pharmacists will verify your details and provide you with a detailed cost estimate.

Secure payment

03

Confirm & Make Payment

Discuss any queries, approve the estimate, and complete your payment.

Worldwide delivery

04

Get Delivered

Your medicines, safely packed and delivered to your door or nearest airport — hassle-free.

Quality You Can Trust

Our internationally recognized certifications underscore our commitment to safety, quality, and excellence.