Product image of Inuxair (Beclometasone Dipropionate, Formoterol Fumarate Dihydrate) supplied by GNH India

Inuxair

Active Ingredient:
Beclometasone Dipropionate, Formoterol Fumarate Dihydrate
Origin:
EU

Inuxair (Beclometasone Dipropionate, Formoterol Fumarate Dihydrate)

Beclometasone dipropionate, the active ingredient in Inuxair, is a corticosteroid presented as an inhalation aerosol (pressurised metered‑dose inhaler) for inhalation use. It treats asthma and chronic obstructive pulmonary disease (COPD) as maintenance therapy in adults and adolescents. GNH India supplies Inuxair as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Chiesi Farmaceutici S.P.A.

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Indications & Clinical Uses

  • Inuxair combines a corticosteroid and a long‑acting β2‑agonist to provide maintenance therapy for obstructive airway diseases.
  • Asthma: reduces airway inflammation and improves symptom control.
  • COPD: decreases exacerbations and enhances lung function.
  • Exercise‑induced bronchoconstriction: offers prophylactic bronchodilation for activity‑related symptoms.

How It Works

  • Beclometasone dipropionate binds intracellular glucocorticoid receptors, modulating gene transcription to suppress inflammatory cytokines, chemokines and adhesion molecules in airway tissues. Formoterol selectively activates β2‑adrenergic receptors on bronchial smooth muscle, increasing cyclic AMP levels, which relaxes the muscle and produces sustained bronchodilation for up to 12 hours.

Side Effects

Common Side Effects

  • Oral thrush or candidiasis
  • Hoarseness or voice change
  • Cough or throat irritation
  • Headache
  • Tremor
  • Dry mouth

Serious or Rare Side Effects

  • Paradoxical bronchospasm
  • Severe allergic reaction (anaphylaxis)
  • Adrenal suppression with prolonged use
  • Pneumonia or respiratory infection
  • Cardiac arrhythmia or tachycardia
  • Significant hypokalemia

Precautions & Warnings

Before using Inuxair, consider the following precautions:

  • Assess inhaler technique: ensure correct use to achieve optimal dosing.
  • Monitor for oral candidiasis: rinse mouth after each inhalation.
  • Screen for cardiovascular disease: β2‑agonist may affect heart rate and rhythm.
  • Use the lowest effective dose: minimize systemic corticosteroid exposure.
  • Avoid use in patients with known hypersensitivity to any component.
  • Store at room temperature: keep inhaler in original pack, protect from moisture and heat.

Avoid Interactions

Inuxair may interact with other medicines as follows:

Major Interactions (Avoid)

  • Beta‑blockers: can reduce bronchodilator effectiveness and precipitate bronchospasm.
  • MAO inhibitors or tricyclic antidepressants: may increase cardiovascular side effects.
  • Diuretics: can potentiate hypokalemia caused by the β2‑agonist.

Moderate Interactions (Monitor Closely)

  • Other inhaled corticosteroids: increase total systemic steroid load.
  • CYP3A4 inhibitors (e.g., ritonavir): may raise formoterol plasma concentrations.
  • Theophylline: additive bronchodilator effect may increase risk of side effects.

Frequently Asked Questions

Inuxair is a fixed‑dose combination inhaler containing beclometasone dipropionate and formoterol fumarate dihydrate. It is indicated for maintenance treatment of asthma and chronic obstructive pulmonary disease (COPD) in adults and adolescents, helping to control symptoms, reduce exacerbations and improve lung function when used regularly as prescribed.

Beclometasone dipropionate is a synthetic glucocorticoid that binds to intracellular glucocorticoid receptors in airway cells. This interaction modulates gene transcription, suppressing the production of inflammatory cytokines, chemokines and adhesion molecules, thereby reducing airway inflammation and hyper‑responsiveness.

Formoterol is a selective long‑acting β2‑adrenergic receptor agonist. Activation of β2 receptors on bronchial smooth muscle increases intracellular cyclic AMP, leading to relaxation of the airway smooth muscle and bronchodilation that lasts for up to 12 hours, providing symptom relief.

The prescribed dose of Inuxair is individualized by the treating physician based on disease severity, patient age, and response to therapy. The prescriber determines the number of inhalations per day and may adjust the regimen during follow‑up visits; patients should follow the specific instructions on the prescription label.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Inuxair combines an inhaled corticosteroid with a long‑acting β2‑agonist in a single device, offering both anti‑inflammatory and bronchodilator effects. Compared with single‑component inhalers, it reduces the need for multiple devices and can improve adherence, while providing comparable efficacy to other combination products such as budesonide/formoterol or fluticasone/salmeterol.

Inuxair should be stored at room temperature, below 25 °C, in its original packaging to protect it from moisture and heat. Do not expose the inhaler to extreme temperatures or direct sunlight, and keep the mouthpiece clean to maintain proper dosing performance.

Inuxair is delivered via a pressurised metered‑dose inhaler. The patient should shake the inhaler, exhale fully, place the mouthpiece between the lips, and press the canister while inhaling slowly and deeply. After each dose, hold the breath for about 10 seconds, then exhale gently. Rinsing the mouth after use helps reduce oral side effects.

Serious adverse events, although rare, can include paradoxical bronchospasm, severe allergic reactions such as anaphylaxis, adrenal suppression from prolonged corticosteroid exposure, and cardiovascular effects like tachycardia or arrhythmias due to the β2‑agonist component. Patients should seek immediate medical attention if they experience sudden worsening of breathing, swelling, or chest pain.

Inuxair is contraindicated in individuals with known hypersensitivity to beclometasone dipropionate, formoterol fumarate, or any excipients in the inhaler. It should also be avoided in patients who have experienced severe asthma attacks requiring oral corticosteroids, or in those with certain cardiac conditions where β2‑agonists may be unsafe, unless a physician determines that benefits outweigh risks.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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