Product image of Inuxair (Formoterol Fumarate Dihydrate, Beclometasone Dipropionate Anhydrous) supplied by GNH India

Inuxair

Active Ingredient:
Formoterol Fumarate Dihydrate, Beclometasone Dipropionate Anhydrous
Origin:
EU

Inuxair (Formoterol Fumarate Dihydrate, Beclometasone Dipropionate Anhydrous)

Formoterol fumarate dihydrate and beclometasone dipropionate anhydrous, the active ingredient in Inuxair, is an inhaled corticosteroid/long‑acting β2‑agonist combination presented as an inhalation aerosol for inhalation use. It is indicated for the maintenance treatment of asthma and chronic obstructive pulmonary disease (COPD) in adults.

GNH India supplies Inuxair as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide. The company adheres to stringent quality standards and provides regulatory documentation to support global distribution. Customers benefit from reliable supply chains, on‑time delivery, and dedicated technical support throughout the procurement process.

Manufacturer / TM Owner

Chiesi Farmaceutici S.P.A.

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Indications & Clinical Uses

  • Inuxair is used as a maintenance inhaler that targets airway inflammation and bronchoconstriction in respiratory disease.
  • Asthma: improves symptom control and reduces exacerbations.
  • COPD: enhances lung function and decreases breathlessness.
  • Chronic bronchitis (a component of COPD): reduces airway inflammation and frequency of flare‑ups.

How It Works

  • Beclometasone dipropionate binds to intracellular glucocorticoid receptors, modulating gene transcription to suppress inflammatory cytokines, eosinophil activity and airway edema. Formoterol fumarate dihydrate selectively stimulates β2‑adrenergic receptors on airway smooth muscle, increasing cyclic AMP levels and producing prolonged bronchodilation lasting up to 12 hours. This synergy allows once‑daily or twice‑daily dosing as directed by a healthcare professional.

Side Effects

Inuxair may cause a range of adverse reactions, most of which are mild and transient.

Common Side Effects

  • Throat irritation or soreness
  • Cough
  • Hoarseness or voice change
  • Oral candidiasis (thrush)
  • Headache
  • Tremor

Serious or Rare Side Effects

  • Paradoxical bronchospasm
  • Severe allergic reaction (anaphylaxis)
  • Pneumonia
  • Cardiac arrhythmia or tachycardia
  • Hyperglycemia
  • Adrenal suppression

Precautions & Warnings

  • Before prescribing Inuxair, clinicians should evaluate patient history and follow safety guidelines.
  • Assess for active infections: avoid use during untreated bacterial, viral or fungal respiratory infections.
  • Monitor for tuberculosis: screen patients with risk factors before initiating therapy.
  • Use lowest effective dose: titrate to control symptoms while minimizing exposure.
  • Avoid abrupt discontinuation: taper under medical supervision to prevent loss of control.
  • Educate on inhaler technique: ensure proper mouth rinsing after use to reduce oral candidiasis.
  • Store at ambient temperature below 25°C: keep in original container, protect from moisture and direct sunlight.

Avoid Interactions

Inuxair can interact with other medicines that affect the respiratory or cardiovascular systems.

Major Interactions (Avoid)

  • Beta‑blockers: may diminish bronchodilator effect and precipitate bronchospasm.
  • Monoamine oxidase inhibitors (MAOIs) or tricyclic antidepressants: increase risk of cardiovascular side effects from formoterol.
  • Strong CYP3A4 inhibitors (e.g., ketoconazole, itraconazole): raise systemic exposure to formoterol, raising risk of tachycardia.

Moderate Interactions (Monitor Closely)

  • Diuretics: may potentiate hypokalemia caused by β2‑agonists.
  • Theophylline: additive stimulatory effect on the heart may increase arrhythmia risk.
  • Other inhaled corticosteroids: cumulative steroid load may increase risk of systemic effects.

Frequently Asked Questions

Inuxair is a prescription inhaler that combines an inhaled corticosteroid with a long‑acting β2‑agonist. It is indicated for the maintenance treatment of asthma and chronic obstructive pulmonary disease (COPD) in adult patients, helping to control symptoms, reduce exacerbations, and improve lung function when used regularly as directed by a healthcare professional.

The beclometasone component binds to glucocorticoid receptors in airway cells, suppressing inflammatory gene expression and reducing swelling, mucus, and immune cell infiltration. Formoterol activates β2‑adrenergic receptors on airway smooth muscle, increasing cyclic AMP and causing prolonged relaxation of the bronchi. Together they provide anti‑inflammatory and bronchodilatory effects in a single inhalation.

The specific dose and dosing schedule of Inuxair are determined by the prescribing clinician based on the severity of the patient’s asthma or COPD, age, and response to therapy. Typical regimens may involve one or two inhalations daily, but the exact number of puffs, strength, and timing must be individualized and written on the prescription.

Safety data for Inuxair in pregnancy and lactation are limited. The potential benefits of controlling severe asthma or COPD may outweigh theoretical risks, but the product should only be used during pregnancy or while breastfeeding if clearly indicated by a qualified healthcare provider. The prescriber should assess the risk‑benefit profile for each patient.

To place an order, submit an enquiry on the Inuxair product page at gnhindia.com, specifying the required quantity and providing your institutional or trade credentials. GNH India’s commercial team will verify eligibility, then respond with pricing, availability, shipping details—including any cold‑chain requirements if applicable—and assist with the necessary import documentation.

Compared with single‑component inhalers, Inuxair offers the convenience of delivering both an inhaled corticosteroid and a long‑acting β2‑agonist in one device, which can improve adherence. Relative to other combination products, its specific ratio of formoterol to beclometasone may provide a distinct balance of anti‑inflammatory and bronchodilator potency, but clinical choice depends on individual response, guideline recommendations, and physician preference.

Inuxair should be stored at ambient temperature below 25 °C, in its original packaging, protected from moisture, heat and direct sunlight. The inhaler should be kept upright and the mouthpiece cleaned regularly according to the manufacturer’s instructions. Do not expose the device to freezing conditions, and replace it after the recommended number of doses has been delivered.

Inuxair is delivered via a metered‑dose inhaler. The patient should exhale fully, place the mouthpiece between the lips, and press the canister to release a puff while inhaling slowly and deeply. After holding the breath for about 5–10 seconds, the patient should exhale gently. Proper technique, including rinsing the mouth after use, helps maximize drug delivery and reduce oral side effects.

The most serious adverse reactions associated with Inuxair include paradoxical bronchospasm, severe allergic reactions such as anaphylaxis, and cardiovascular events like tachycardia, arrhythmias, or hypertension, especially in patients with underlying heart disease. Patients should seek immediate medical attention if they experience sudden worsening of breathing, chest pain, rapid heartbeat, or signs of an allergic reaction.

Inuxair is contraindicated in patients with known hypersensitivity to either formoterol, beclometasone, or any excipients in the inhaler. It should also be avoided in individuals who have experienced a severe asthma attack or COPD exacerbation triggered by a β‑agonist, as well as in patients with untreated respiratory infections that could worsen with corticosteroid therapy. Clinicians must evaluate each patient’s medical history before prescribing.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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