Product image of Invita D3 (Colecalciferol) supplied by GNH India

Invita D3

Active Ingredient:
Colecalciferol
Origin:
EU

Invita D3 (Colecalciferol)

Colecalciferol, the active ingredient in Invita D3, is a vitamin D presented as an oral dietary supplement for oral administration. It helps maintain normal calcium and phosphate concentrations in the blood and is employed to prevent or correct vitamin D deficiency in both children and adults.

GNH India supplies Invita D3 as a licensed, GDP‑compliant international pharmaceutical supplier, providing the product to hospitals, pharmacies, and clinical centres across global markets. The company adheres to stringent quality standards and offers reliable logistics for timely delivery.

Manufacturer / TM Owner

Consilient Health Ltd

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Indications & Clinical Uses

Invita D3 (colecalciferol) is used to address disorders of vitamin D metabolism and related calcium homeostasis.

  • Vitamin D deficiency: restores adequate serum 25‑hydroxyvitamin D levels to support bone health.
  • Osteomalacia: promotes mineralization of the bone matrix in adults with softening of bones.
  • Rickets: aids in proper bone development and growth in children with deficient vitamin D.
  • Hypocalcemia due to vitamin D deficiency: increases calcium absorption to normalize serum calcium.

How It Works

  • Colecalciferol is converted in the liver to 25‑hydroxyvitamin D and subsequently in the kidney to the active hormone calcitriol. Calcitriol binds to the vitamin D receptor (VDR) in target cells, forming a complex that regulates gene transcription, thereby enhancing intestinal absorption of calcium and phosphate and supporting bone mineralization.

Side Effects

Common Side Effects

  • Hypercalcemia: elevated blood calcium levels causing fatigue or nausea.
  • Nausea: mild gastrointestinal discomfort after ingestion.
  • Headache: transient mild head pain.
  • Dry mouth: reduced salivary flow.
  • Constipation: occasional difficulty passing stools.

Serious or Rare Side Effects

  • Hypercalciuria: excessive urinary calcium excretion leading to kidney stones.
  • Severe hypercalcemia: may cause cardiac arrhythmias or neurological symptoms.
  • Allergic reaction: rash, itching, or swelling indicating hypersensitivity.

Precautions & Warnings

Before initiating therapy, consider the following precautions:

  • Assess baseline serum calcium: check levels to avoid hypercalcemia.
  • Monitor vitamin D status: periodic measurement of 25‑OH vitamin D recommended.
  • Avoid excessive calcium intake: counsel patients on dietary sources.
  • Use caution in renal impairment: adjust monitoring frequency.
  • Pregnancy and lactation: consult healthcare provider before use.
  • Store at ambient temperature: keep in original container, protect from moisture and light.

Avoid Interactions

Potential drug interactions include

Major Interactions (Avoid)

  • Thiazide diuretics: may increase risk of hypercalcemia.
  • High-dose vitamin A: synergistic effect leading to hypercalcemia.
  • Aluminum-containing antacids: can reduce vitamin D absorption.

Moderate Interactions (Monitor Closely)

  • Corticosteroids: may diminish vitamin D effectiveness.
  • Orlistat: may decrease absorption of fat‑soluble vitamins.
  • Anticonvulsants (phenytoin, phenobarbital): may increase vitamin D metabolism.

Frequently Asked Questions

Invita D3 contains colecalciferol, a form of vitamin D3, and is used to prevent or treat vitamin D deficiency, support calcium and phosphate balance, and aid in the management of bone‑related conditions such as osteomalacia and rickets.

Colecalciferol is converted first to 25‑hydroxyvitamin D in the liver and then to the active hormone calcitriol in the kidneys. Calcitriol binds to vitamin D receptors, regulating genes that increase intestinal absorption of calcium and phosphate, essential for bone mineralization.

The appropriate dose of Invita D3 is determined by a healthcare professional based on the patient’s age, vitamin D status, and clinical condition. Dosage recommendations are individualized and should follow the prescriber’s instructions.

Safety of Invita D3 in pregnancy or lactation should be evaluated by a qualified healthcare provider. The prescriber will consider the potential benefits and risks before recommending use in these populations.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details, and necessary import documentation.

Invita D3 provides colecalciferol, the natural form of vitamin D3, which is generally preferred over vitamin D2 for its higher potency and longer duration of action. It offers comparable efficacy to other oral vitamin D3 products when dosed appropriately.

Invita D3 should be stored at ambient temperature, below 25 °C, in its original packaging. Protect the product from moisture, direct sunlight, and excessive heat to maintain stability and potency.

Invita D3 is taken orally, typically with or without food, as directed by a healthcare professional. The exact administration method and timing should follow the prescriber’s guidance.

Serious risks include hypercalcemia and hypercalciuria, which can lead to kidney stones, cardiac arrhythmias, or neurological symptoms. Patients should be monitored for signs of elevated calcium levels, especially when high doses are used.

Individuals with known hypersensitivity to colecalciferol or any excipients, those with severe hypercalcemia, or patients with certain disorders of calcium metabolism should avoid using Invita D3 unless advised otherwise by a qualified clinician.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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