Product image of Iodure (131i) De Sodium Pour Therapie Curiumpharma (Sodium Iodide (131i)) supplied by GNH India

Iodure (131i) De Sodium Pour Therapie Curiumpharma

Active Ingredient:
Sodium Iodide (131i)
Origin:
EU

Iodure (131i) De Sodium Pour Therapie Curiumpharma (Sodium Iodide (131i))

Sodium Iodide (131I), the active ingredient in Iodure (131i) De Sodium Pour Therapie Curiumpharma, is a radioactive iodine presented as an oral radiopharmaceutical for oral use. It is employed in the treatment of thyroid cancer and hyperthyroidism in adult patients.

GNH India supplies Iodure (131i) De Sodium Pour Therapie Curiumpharma as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, oncology centres and pharmacies worldwide.

Manufacturer / TM Owner

Curium Netherlands B.V.

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Indications & Clinical Uses

Iodure (Sodium Iodide 131I) is a radioactive iodine used in therapeutic protocols targeting thyroid tissue.

  • Thyroid cancer: delivers targeted radiation to destroy malignant thyroid cells and reduce tumor burden.
  • Hyperthyroidism: ablates overactive thyroid tissue to restore normal hormone production.
  • Pre‑surgical thyroid ablation: reduces gland size and activity before thyroidectomy, facilitating safer surgery.

How It Works

  • Sodium Iodide (131I) is selectively taken up by thyroid follicular cells via the sodium‑iodide symporter. Once internalized, the isotope emits beta particles that cause localized cellular damage, leading to selective destruction of thyroid tissue while sparing surrounding structures. This targeted radiative effect underlies its therapeutic use in thyroid malignancies and hyperfunctioning disorders.

Side Effects

Iodure (Sodium Iodide 131I) may cause a range of adverse reactions following oral administration.

Common Side Effects

  • Nausea or vomiting: transient gastrointestinal upset after dosing.
  • Neck discomfort or pain: irritation of thyroid tissue.
  • Salivary gland swelling: temporary enlargement and tenderness.
  • Dry mouth or altered taste: reduced salivary flow.

Serious or Rare Side Effects

  • Bone marrow suppression: decreased blood cell counts requiring monitoring.
  • Severe hypothyroidism: excessive loss of thyroid function.
  • Radiation thyroiditis: painful inflammation of the gland.
  • Allergic reaction: rash, itching, or anaphylaxis in rare cases.

Precautions & Warnings

Prior to prescribing Iodure (Sodium Iodide 131I), clinicians should consider several safety measures.

  • Thyroid function assessment: confirm diagnosis and baseline hormone levels.
  • Pregnancy evaluation: avoid use in pregnant individuals unless benefits outweigh risks.
  • Concomitant medication review: identify agents that may interfere with iodine uptake.
  • Hematologic monitoring: check blood counts before and after therapy.
  • Radiation safety counseling: educate patients on post‑treatment precautions.
  • Store at ambient temperature: keep in original packaging, protect from moisture and light.

Avoid Interactions

Iodure (Sodium Iodide 131I) can interact with other medicines that affect thyroid function or bone marrow.

Major Interactions (Avoid)

  • Antithyroid drugs (e.g., propylthiouracil, methimazole): reduce therapeutic uptake.
  • Lithium: may alter thyroid hormone dynamics and increase toxicity.
  • Amiodarone: interferes with iodine metabolism and uptake.

Moderate Interactions (Monitor Closely)

  • Levothyroxine: dose may need adjustment after ablation.
  • Chemotherapy agents: overlapping risk of bone marrow suppression.
  • Beta‑blockers: can mask symptoms of thyroid storm.
  • Corticosteroids: may affect inflammatory response post‑treatment.

Frequently Asked Questions

Iodure (131i) De Sodium Pour Therapie Curiumpharma contains Sodium Iodide (131I) and is used as a therapeutic radiopharmaceutical to treat thyroid cancer and to manage hyperthyroidism by delivering targeted radiation to thyroid tissue.

Sodium Iodide (131I) is actively taken up by thyroid cells via the sodium‑iodide symporter. The isotope then emits beta radiation that selectively destroys thyroid cells, reducing tumor burden in cancer or ablating overactive tissue in hyperthyroidism.

The exact dose of Iodure (131i) is determined by the prescribing physician based on the patient’s condition, thyroid size, and treatment goals. Dosing is individualized and should follow the clinician’s recommendation.

Radioactive iodine is generally contraindicated in pregnancy because it can affect the developing fetus. Breastfeeding mothers should also avoid use, as the isotope can be secreted in milk. Consultation with a specialist is essential.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Iodure (Sodium Iodide 131I) is comparable to other 131I preparations such as NaI‑131 capsules, offering the same beta‑emitting radiation for thyroid ablation. Differences may lie in formulation, regulatory status, or supplier reliability rather than pharmacologic effect.

Iodure should be stored at ambient temperature, below 25 °C, in its original container. Protect the product from moisture, direct sunlight and physical damage to maintain its radiochemical stability.

Iodure is taken orally as a single dose under medical supervision. The patient swallows the capsule or tablet with water, and radiation safety guidelines are followed to limit exposure to others.

Serious risks include bone marrow suppression, severe hypothyroidism, radiation thyroiditis and rare allergic reactions. Patients should be monitored for blood count changes and thyroid function after treatment.

Individuals who are pregnant, breastfeeding, have untreated severe hypothyroidism, or are taking medications that block iodine uptake (e.g., antithyroid drugs) should not receive Iodure unless a specialist determines that benefits outweigh the risks.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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