Product image of Ioduro (131i) De Sodio Ge Healthcare (Sodium Iodide (131i)) supplied by GNH India

Ioduro (131i) De Sodio Ge Healthcare

Active Ingredient:
Sodium Iodide (131i)
Origin:
EU

Ioduro (131i) De Sodio Ge Healthcare (Sodium Iodide (131i))

Sodium Iodide (131I), the active ingredient in Ioduro (131i) De Sodio, is a radioactive iodine presented as an oral solution for oral use. It is used in the diagnosis and treatment of thyroid disorders, including imaging, cancer therapy, and hyperthyroidism.

GNH India supplies Ioduro (131i) De Sodio as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, transplant centres, oncology centres, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Ge Healthcare Bio-Sciences, S.A.U.

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Indications & Clinical Uses

  • Ioduro (Sodium Iodide 131I) is employed in the thyroid pathway for both diagnostic and therapeutic purposes.
  • Thyroid imaging: Enables visualization of thyroid tissue using radioactive uptake for diagnostic scans.
  • Thyroid cancer treatment: Delivers targeted radiation to thyroid carcinoma cells to reduce tumor burden.
  • Hyperthyroidism: Provides therapeutic radiation to suppress overactive thyroid tissue.

How It Works

  • Sodium Iodide (131I) is taken up selectively by thyroid follicular cells via the sodium‑iodide symporter. Once inside the gland, the emitted beta particles deliver localized radiation that can be captured by imaging equipment for diagnostic purposes or used to destroy hyperactive or malignant thyroid tissue in therapeutic settings.

Side Effects

Adverse reactions may occur following oral administration of radioactive iodine.

Common Side Effects

  • Nausea or vomiting
  • Altered taste sensation
  • Mild salivary gland discomfort
  • Transient fatigue
  • Temporary hypothyroidism
  • Mild headache

Serious or Rare Side Effects

  • Severe hypothyroidism requiring hormone replacement
  • Radiation thyroiditis
  • Bone marrow suppression
  • Allergic reactions such as rash or anaphylaxis
  • Radiation‑induced sialadenitis
  • Rare secondary malignancies

Precautions & Warnings

  • Use of Ioduro requires careful consideration of patient‑specific factors and handling requirements.
  • Pregnancy: Use only if clearly needed; potential fetal radiation exposure.
  • Breastfeeding: Contraindicated; iodine may be secreted in milk.
  • Renal impairment: Adjust dose; reduced clearance may increase systemic exposure.
  • Thyroid function: Baseline assessment required before administration.
  • Drug interactions: Avoid concurrent high‑iodine substances.
  • Store at ambient temperature: Keep below 25°C, in the original container, protected from moisture and light.

Avoid Interactions

Ioduro may interact with other medications that affect iodine handling or thyroid function.

Major Interactions (Avoid)

  • Antithyroid drugs (e.g., propylthiouracil, methimazole): May reduce uptake of radioactive iodine.
  • High‑iodine contrast agents: Can block thyroid uptake of I‑131.
  • Lithium carbonate: Increases retention of iodine in the thyroid, altering therapeutic effect.

Moderate Interactions (Monitor Closely)

  • Amiodarone: Contains iodine and may affect dosing.
  • Corticosteroids: May modify inflammatory response after therapy.
  • Diuretics: May affect renal clearance of iodine.

Frequently Asked Questions

Ioduro (131i) De Sodio, containing Sodium Iodide (131I), is used for thyroid imaging, treatment of thyroid cancer, and management of hyperthyroidism. The radioactive iodine is taken up by thyroid tissue, allowing clinicians to visualize the gland or deliver localized radiation to abnormal cells.

Sodium Iodide (131I) is absorbed by thyroid cells via the sodium‑iodide symporter. Once inside, the isotope emits beta particles that either generate images for diagnostic scans or provide therapeutic radiation that destroys overactive or malignant thyroid tissue while sparing most surrounding structures.

The dose of Ioduro (131i) De Sodio is individualized and determined by the prescribing physician based on the specific indication, patient weight, thyroid function, and treatment goals. No standard dosing can be provided without a medical assessment.

Radioactive iodine can cross the placenta and be secreted in breast milk, posing potential risks to the fetus or infant. Use during pregnancy or lactation is only considered when the benefit outweighs the risk and should be guided by a specialist.

To order, submit an enquiry on the product page at gnhindia.com indicating the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including any cold‑chain needs) and import documentation.

Ioduro delivers Sodium Iodide (131I) in an oral solution, similar to other I‑131 preparations. Differences may lie in formulation purity, regulatory approvals, and supply chain reliability. Clinicians choose based on local licensing, dosing flexibility, and the supplier’s ability to meet quality and delivery standards.

Ioduro should be stored at ambient temperature, preferably below 25 °C, in its original sealed container. Protect the solution from moisture, direct sunlight, and physical damage. Follow local regulations for handling radioactive materials and keep it out of reach of unauthorized personnel.

Ioduro is administered orally as a measured volume of solution. The patient drinks the dose under medical supervision, often after fasting or following specific preparation instructions to optimize thyroid uptake. Administration details are provided by the treating physician.

Serious risks include severe hypothyroidism, radiation thyroiditis, bone‑marrow suppression, allergic reactions, and, rarely, secondary malignancies. Patients should be monitored for signs of these events, and any sudden symptoms such as fever, unexplained bruising, or severe neck pain should prompt immediate medical evaluation.

Ioduro is contraindicated in pregnant or breastfeeding women unless absolutely necessary, individuals with known hypersensitivity to iodine or radioactive compounds, and patients with uncontrolled severe renal impairment where clearance cannot be assured. A thorough clinical assessment is required before use.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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