Product image of Iohexagita (Iohexol) supplied by GNH India

Iohexagita

Active Ingredient:
Iohexol
Origin:
EU

Iohexagita (Iohexol)

Iohexol, the active ingredient in Iohexagita, is an iodinated contrast agent presented as a sterile injectable solution for intravenous or intra‑arterial use. It enhances radiographic visibility of vascular structures and organs during diagnostic imaging procedures.
GNH India supplies Iohexagita as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, imaging centres and clinics worldwide.

Manufacturer / TM Owner

T2pharma Gmbh

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Indications & Clinical Uses

Iohexagita is used as an iodinated contrast medium in various diagnostic imaging procedures.

  • Computed Tomography (CT): improves visualization of soft tissues, vessels and organs.
  • Angiography: delineates arterial and venous anatomy for cardiovascular assessment.
  • Intravenous urography: enhances detection of urinary tract abnormalities.
  • Arthrography: provides contrast for joint space evaluation.
  • Myelography: outlines spinal canal and nerve roots for neurological imaging.

How It Works

  • Iohexol increases the attenuation of X‑rays by providing high radiodensity due to its iodine atoms. After intra‑arterial or intravenous administration, it distributes within the vascular and extracellular compartments, temporarily raising the contrast between blood‑filled structures and surrounding tissues, thereby allowing detailed radiographic imaging of organs and vessels.

Side Effects

Adverse reactions to Iohexagita may range from mild to severe and are reported following administration of iodinated contrast agents.

Common Side Effects

  • Warmth or flushing sensation at injection site.
  • Metallic taste in the mouth.
  • Nausea or vomiting.
  • Headache or dizziness.
  • Mild urticaria or itching.
  • Transient increase in blood pressure.

Serious or Rare Side Effects

  • Anaphylactic or severe allergic reaction.
  • Acute renal failure, especially in patients with pre‑existing kidney disease.
  • Cardiac arrhythmias or hypotension.
  • Seizures or neurologic disturbances.
  • Pulmonary edema.
  • Persistent skin rash or Stevens‑Johnson syndrome.

Precautions & Warnings

When using Iohexagita, clinicians should assess patient history and monitor for potential complications.

  • Renal function: evaluate creatinine clearance before administration.
  • Allergy history: screen for prior reactions to iodinated contrast.
  • Thyroid disease: consider risk of iodine‑induced thyroid dysfunction.
  • Diabetes: suspend metformin in at‑risk patients per guidelines.
  • Hydration: ensure adequate fluid intake to reduce nephrotoxicity.

Store below 25°C: keep in original container, protect from light and moisture.

Avoid Interactions

Iohexagita may interact with other medications, influencing safety or efficacy.

Major Interactions (Avoid)

  • Metformin: risk of lactic acidosis in renal impairment; discontinue before contrast.
  • Thyroid hormone preparations: excess iodine may alter thyroid function.
  • Radioactive iodine therapy: iodine load can interfere with treatment efficacy.

Moderate Interactions (Monitor Closely)

  • NSAIDs and diuretics: may increase risk of contrast‑induced nephropathy.
  • ACE inhibitors or ARBs: monitor renal function and blood pressure.
  • Beta‑blockers: may mask tachycardia associated with allergic reactions.

Frequently Asked Questions

Iohexagita is an iodinated contrast agent used to enhance X‑ray based imaging studies such as computed tomography, angiography, urography, arthrography and myelography. By increasing radiodensity, it helps clinicians obtain clearer images of blood vessels, organs and tissues for accurate diagnosis.

Iohexol contains iodine atoms that strongly absorb X‑rays. After intravenous or intra‑arterial injection, it circulates through the vascular system and temporarily raises the X‑ray attenuation of blood‑filled structures, creating a contrast difference between those structures and surrounding tissues, which produces detailed radiographic images.

The dose of Iohexagita is determined by the prescribing physician based on the specific imaging procedure, patient weight, renal function and the required level of contrast. Dosage calculations are individualized and should follow the relevant clinical guidelines and product labeling.

The safety of Iohexagita in pregnancy and lactation has not been definitively established. It is classified as pregnancy category unknown, and the decision to use it should be based on a careful risk‑benefit assessment by the treating physician, considering the importance of the diagnostic information.

To order Iohexagita, submit an enquiry on the product page at gnhindia.com with the required quantity. GNH India supplies hospitals, pharmacies and procurement teams worldwide. After verification of trade or institutional credentials, the sales team will provide pricing, availability, shipping details (including any cold‑chain requirements) and assist with import documentation.

Iohexagita (Iohexol) is a non‑ionic, low‑osmolality iodinated contrast medium, offering a favorable safety profile compared with older high‑osmolality agents. It provides comparable image quality while reducing the incidence of discomfort and adverse reactions, making it a preferred choice for many diagnostic imaging procedures.

Iohexagita should be stored below 25 °C in its original packaging, protected from light and moisture. The container must be kept sealed until use, and any opened vial should be used promptly according to the product’s stability guidelines to maintain sterility and efficacy.

Iohexagita is administered by a trained healthcare professional via intravenous or intra‑arterial injection. The injection rate and volume are tailored to the specific imaging study, and patients are monitored during and after administration for any immediate reactions.

The most serious risks include severe allergic reactions such as anaphylaxis, contrast‑induced nephropathy leading to acute renal failure, and rare cardiac events like arrhythmias or hypotension. Prompt recognition and management of these reactions are essential during and after administration.

Iohexagita should be avoided in patients with a known hypersensitivity to iodinated contrast agents, severe renal impairment without adequate hydration, uncontrolled hyperthyroidism, or those who are pregnant or breastfeeding unless the diagnostic benefit outweighs the potential risk.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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