Product image of Iohexol Ge Healthcare (Iohexol) supplied by GNH India

Iohexol Ge Healthcare

Active Ingredient:
Iohexol
Origin:
EU

Iohexol Ge Healthcare (Iohexol)

Iohexol, the active ingredient in Iohexol Ge Healthcare, is an iodinated contrast agent presented as a solution for injection for intraarterial, intrathecal, intravenous use. It provides radiodensity for diagnostic imaging in patients undergoing angiography, CT, myelography, urography, and other contrast‑enhanced radiographic examinations.

GNH India supplies Iohexol Ge Healthcare as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, transplant centres, oncology centres, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Ge Healthcare Limited

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Indications & Clinical Uses

  • Iohexol is employed in diagnostic imaging procedures that require enhanced radiographic contrast.
  • Angiography: improves visualization of blood vessels and vascular pathology.
  • Computed tomography (CT) imaging: increases tissue contrast for detailed cross‑sectional images.
  • Myelography: delineates spinal canal structures and nerve roots.
  • Urography: highlights the urinary tract for functional assessment.
  • Contrast‑enhanced radiographic examinations: provides clearer images of organs and lesions.

How It Works

  • Iohexol is a non‑ionic, water‑soluble iodine‑containing compound. After intra‑arterial, intravenous or intrathecal injection, the iodine atoms absorb X‑ray photons, raising the radiodensity of blood, extracellular fluid and tissues. This differential absorption creates enhanced contrast between anatomical structures, allowing clearer visualization in imaging studies. The agent distributes in the extracellular space and is eliminated unchanged by renal excretion.

Side Effects

Adverse reactions may occur following administration of Iohexol.

Common Side Effects

  • Warmth or flushing sensation at the injection site
  • Nausea or mild vomiting
  • Metallic taste in the mouth
  • Mild headache or dizziness

Serious or Rare Side Effects

  • Anaphylactic or severe allergic reaction
  • Acute renal impairment or contrast‑induced nephropathy
  • Pulmonary edema or respiratory distress
  • Cardiac arrhythmias or severe hypotension

Precautions & Warnings

  • Prior to using Iohexol, several safety considerations should be observed.
  • Assess renal function: evaluate creatinine clearance to identify patients at risk of nephrotoxicity.
  • Check allergy history: avoid in individuals with known iodine or contrast media hypersensitivity.
  • Maintain hydration: ensure adequate fluid intake before and after administration.
  • Use lowest effective dose: tailor volume to the specific imaging requirement.
  • Store at ambient temperature: keep in original packaging, protect from light and moisture.

Avoid Interactions

Iohexol may interact with other medicines; awareness of these interactions helps minimize risk.

Major Interactions (Avoid)

  • Concurrent nephrotoxic drugs (e.g., high‑dose aminoglycosides)
  • Metformin in patients with reduced renal function
  • Iodine‑containing medications (e.g., amiodarone)

Moderate Interactions (Monitor Closely)

  • Diuretics: monitor fluid balance and renal function
  • ACE inhibitors or ARBs: watch for changes in kidney performance
  • Thyroid hormone therapy: iodine load may affect thyroid status

Frequently Asked Questions

Iohexol Ge Healthcare is a diagnostic imaging agent used to enhance the visibility of blood vessels, organs and tissues during procedures such as angiography, computed tomography (CT), myelography, urography and other contrast‑enhanced radiographic examinations.

Iohexol contains iodine atoms that absorb X‑ray photons. When injected, it increases the radiodensity of the extracellular fluid and vascular spaces, creating a contrast difference between structures and allowing clearer images in X‑ray‑based studies.

The dose of Iohexol is determined by the prescribing clinician based on the specific imaging study, patient size, renal function and the required level of contrast. No fixed regimen is provided; the prescriber tailors the volume to each case.

Safety data for Iohexol during pregnancy and lactation are limited. It should only be used when the diagnostic benefit outweighs potential risks, and the decision must be made by the treating physician in consultation with the patient.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including any cold‑chain needs) and required import documentation.

Iohexol is a non‑ionic, low‑osmolality iodinated contrast medium, offering a favorable safety profile compared with older high‑osmolality agents. Compared with other low‑osmolality agents such as iopamidol, Iohexol provides similar image quality while maintaining comparable rates of adverse reactions.

Iohexol should be stored at ambient temperature, below 25 °C, in its original container. Protect the solution from direct sunlight, moisture and extreme temperatures. Do not freeze or shake the vial before use.

Iohexol is supplied as a sterile solution for injection and may be administered intra‑arterially, intravenously or intrathecally, depending on the imaging procedure. Administration is performed by qualified healthcare professionals under controlled conditions.

The most serious risks include severe allergic reactions such as anaphylaxis, contrast‑induced nephropathy leading to acute renal failure, and cardiovascular events like severe hypotension or arrhythmias. Immediate medical attention is required if any of these occur.

Iohexol is contraindicated in patients with a known hypersensitivity to iodine‑containing contrast media, those with severe renal impairment where alternative imaging is possible, and individuals who have experienced prior severe reactions to iodinated contrast agents.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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