Product image of Iohexol Imax (Iohexol) supplied by GNH India

Iohexol Imax

Active Ingredient:
Iohexol
Origin:
EU

Iohexol Imax (Iohexol)

Iohexol, the active ingredient in Iohexol Imax, is an iodinated contrast agent presented as a solution for injection for intra‑arterial and intravenous use. It enhances radiographic visibility during diagnostic imaging procedures in patients undergoing angiography, CT, urography, or arthrography.

GNH India supplies Iohexol Imax as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, transplant centres, oncology centres, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Imax Diagnostic Imaging Limited

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Indications & Clinical Uses

  • Iohexol is used as an iodinated contrast medium to improve visualization of vascular and tissue structures in diagnostic imaging.
  • Angiography: provides enhanced vessel delineation for accurate assessment.
  • Computed tomography (CT) imaging: increases contrast between organs and vessels for detailed cross‑sectional images.
  • Urography: highlights urinary tract anatomy to detect obstruction or lesions.
  • Arthrography: improves joint space visualization for orthopedic evaluation.

How It Works

  • Iohexol is a non‑ionic, water‑soluble iodine‑based compound that absorbs X‑rays, raising the radiodensity of blood and extracellular fluid. Its high osmolarity draws water into the vascular compartment, temporarily increasing contrast between vessels or tissues and surrounding structures, thereby allowing imaging systems to differentiate anatomic details more clearly.

Side Effects

Adverse reactions may occur following administration of Iohexol.

Common Side Effects

  • Warm or flushing sensation at the injection site.
  • Nausea or vomiting.
  • Headache.
  • Metallic taste in the mouth.

Serious or Rare Side Effects

  • Anaphylactic or severe allergic reaction.
  • Acute kidney injury, especially in patients with pre‑existing renal impairment.
  • Cardiovascular collapse or severe hypotension.

Precautions & Warnings

Prior to using Iohexol, several safety considerations should be observed.

  • Assess renal function: evaluate serum creatinine and eGFR before administration.
  • Review allergy history: avoid in patients with known hypersensitivity to iodinated contrast.
  • Ensure adequate hydration: maintain fluid balance to reduce risk of contrast‑induced nephropathy.
  • Pregnancy considerations: use only when benefits outweigh potential risks (Category B).
  • Pediatric use: dose adjustment and careful monitoring are required.
  • Store at ambient temperature: keep in original container, protect from light and moisture.

Avoid Interactions

Iohexol may interact with other medications or agents.

Major Interactions (Avoid)

  • Concurrent use of other iodinated contrast agents.
  • Co‑administration with high‑dose nephrotoxic drugs such as aminoglycosides or NSAIDs.
  • Recent radioactive iodine therapy.

Moderate Interactions (Monitor Closely)

  • Diuretics: may increase risk of renal impairment.
  • ACE inhibitors or ARBs: monitor blood pressure and renal function.
  • Beta‑blockers: observe for potential hemodynamic changes.

Frequently Asked Questions

Iohexol Imax is an iodinated contrast medium used to enhance the visibility of blood vessels and tissues during diagnostic imaging procedures such as angiography, computed tomography (CT), urography, and arthrography. It helps radiologists obtain clearer images for accurate diagnosis.

Iohexol contains iodine atoms that strongly absorb X‑rays. When injected, it increases the radiodensity of the vascular and extracellular spaces, creating a temporary contrast between structures. This heightened contrast enables imaging equipment to differentiate organs, vessels, and tissues more distinctly.

The dose of Iohexol Imax is determined by the prescribing clinician based on the specific imaging study, patient weight, renal function, and the required level of contrast. Healthcare professionals calculate the appropriate volume and concentration for each individual case.

Iohexol Imax is classified as Pregnancy Category B, indicating that animal studies have not shown risk but there are limited human data. It should be used only when the diagnostic benefit outweighs potential risks. Breastfeeding mothers should consult their physician, as the drug may be excreted in milk.

To order Iohexol Imax, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India supplies hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including any cold‑chain requirements) and necessary import documentation.

Iohexol Imax is a non‑ionic, low‑osmolality iodinated contrast agent, offering a favorable safety profile compared with older high‑osmolality agents. It provides comparable image enhancement while reducing the incidence of discomfort and adverse renal effects, making it a preferred choice for many diagnostic procedures.

Iohexol Imax should be stored at ambient temperature, preferably below 25 °C, in its original packaging. Protect the solution from direct light, moisture, and extreme temperature fluctuations. Do not freeze or shake the vial before use.

Iohexol Imax is administered intravenously or intra‑arterially by a qualified healthcare professional. The solution is injected as a bolus or infusion, depending on the imaging protocol, using aseptic technique and appropriate catheter or needle size.

The most serious risks include severe allergic reactions (anaphylaxis), acute kidney injury, and cardiovascular collapse. Patients with known iodine allergy, impaired renal function, or unstable cardiovascular status should be closely monitored, and emergency measures must be readily available.

Iohexol Imax should be avoided in patients with a documented hypersensitivity to iodinated contrast media, those with uncontrolled severe renal impairment, and individuals who have recently undergone radioactive iodine therapy. Clinicians must assess each patient’s medical history before administration.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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