Product image of Iomeron (Iomeprol) supplied by GNH India

Iomeron

Active Ingredient:
Iomeprol
Origin:
EU

Iomeron (Iomeprol)

Iomeprol, the active ingredient in Iomeron, is an iodinated contrast media presented as a 350 mg I/mL injectable solution for intraarterial, intraarticular and intracavitary use. It provides radiographic contrast enhancement for imaging procedures in patients undergoing diagnostic or interventional examinations.

GNH India supplies Iomeron as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, transplant centres, oncology centres, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Bracco Imaging S.P.A.

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Indications & Clinical Uses

Iomeron (iomeprol) is an iodinated contrast agent used to enhance X‑ray based imaging of vascular and tissue structures.

  • Angiography: improves visualization of blood vessels during diagnostic and interventional procedures.
  • Arthrography: delineates joint spaces and structures for orthopedic assessment.
  • Cavitary imaging: outlines pleural, peritoneal or other body cavities to detect fluid collections or lesions.
  • General X‑ray contrast enhancement: increases the contrast of soft‑tissue structures in routine radiographic studies.

How It Works

  • Iomeprol contains a high concentration of iodine atoms that absorb X‑ray photons, thereby increasing attenuation of the X‑ray beam in the vascular and extracellular compartments. After injection, the solution distributes rapidly in the intravascular space and extracellular fluid, providing temporary radiodensity that highlights anatomical details during imaging.

Side Effects

Adverse reactions may occur following administration of Iomeron.

Common Side Effects

  • Warmth or flushing at the injection site.
  • Nausea or mild vomiting.
  • Transient headache or dizziness.
  • Mild metallic taste in the mouth.

Serious or Rare Side Effects

  • Acute hypersensitivity reactions, including urticaria, bronchospasm or anaphylaxis.
  • Contrast‑induced nephropathy, particularly in patients with pre‑existing renal impairment.
  • Thyroid dysfunction due to iodine load, potentially causing hyper‑ or hypothyroidism.
  • Cardiac arrhythmias in susceptible individuals.
  • Severe skin reactions such as Stevens‑Johnson syndrome.

Precautions & Warnings

Prior assessment and monitoring are essential to minimise risks associated with iodinated contrast media.

  • Renal function: evaluate serum creatinine and eGFR before administration.
  • Allergy history: screen for prior reactions to iodine‑containing agents or other contrast media.
  • Thyroid disease: monitor thyroid function in patients with known disorders.
  • Pregnancy: consider risk‑benefit ratio; category B indicates no proven risk in humans.
  • Store at ambient temperature below 25°C: keep in the original container, protect from moisture and light.

Avoid Interactions

Iomeron may interact with certain medications, affecting renal function or iodine balance.

Major Interactions (Avoid)

  • Metformin: risk of lactic acidosis; discontinue before contrast administration and resume after renal function is confirmed.
  • High‑dose iodine supplements: may increase total iodine load and exacerbate thyroid effects.

Moderate Interactions (Monitor Closely)

  • ACE inhibitors, diuretics or NSAIDs: can potentiate contrast‑induced nephropathy; monitor renal parameters.
  • Thyroid hormone replacement: adjust dosing if significant iodine exposure occurs.

Frequently Asked Questions

Iomeron is an iodinated contrast agent used to enhance X‑ray based imaging such as angiography, arthrography, cavitary studies and other radiographic examinations. It improves the visibility of vascular structures, joints and body cavities during diagnostic and interventional procedures.

Iomeprol contains a high concentration of iodine atoms that absorb X‑ray photons. After injection, it distributes in the vascular and extracellular spaces, temporarily increasing radiodensity and allowing detailed visualization of anatomical structures on X‑ray, CT or fluoroscopic images.

The specific dose of Iomeron is determined by the prescribing clinician based on the imaging study, patient size, renal function and the route of administration. Healthcare professionals calculate the appropriate volume to achieve optimal contrast enhancement.

Iomeron is classified as pregnancy category B, indicating no proven risk in human studies, but it should only be used when clearly needed. Limited data are available for breastfeeding; clinicians should weigh potential benefits against risks and consider temporary cessation of breastfeeding if advised.

To order Iomeron, submit an enquiry on the product page at gnhindia.com with the required quantity. GNH India supplies hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Iomeron (iomeprol) offers a high iodine concentration (350 mg I/mL) similar to other non‑ionic, low‑osmolality agents, providing strong radiographic contrast with a favorable safety profile. Compared with older high‑osmolality agents, it typically results in fewer adverse reactions and better patient tolerance.

Iomeron should be stored at ambient temperature below 25 °C, in its original packaging, protected from moisture and direct light. Do not freeze the solution, and avoid shaking vigorously to maintain solution integrity before use.

Iomeron is supplied as an injectable solution and is administered intravenously, intra‑arterially, intra‑articularly or intracavitarily by a qualified healthcare professional. The injection is performed under aseptic conditions using appropriate catheters or syringes according to the imaging protocol.

The most serious risks include acute hypersensitivity reactions such as anaphylaxis, contrast‑induced nephropathy in patients with impaired renal function, and thyroid dysfunction due to iodine load. Prompt recognition and appropriate medical management are essential if these events occur.

Iomeron should be avoided in patients with a known severe allergy to iodinated contrast media, uncontrolled hyperthyroidism, or severe renal impairment where the risk of nephropathy outweighs the diagnostic benefit. Clinicians must assess each patient individually before administration.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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