Product image of Iomeron (Iomeprol) supplied by GNH India

Iomeron

Active Ingredient:
Iomeprol
Origin:
EU

Iomeron (Iomeprol)

Iomeprol, the active ingredient in Iomeron, is an iodinated contrast media presented as a 350 mg I/mL solution for injection for intraarterial, intraarticular, and intrathecal use. It enhances radiographic contrast in diagnostic imaging procedures such as angiography, arthrography, myelography, and CT scans.

GNH India supplies Iomeron as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, imaging centres, and clinics worldwide.

Manufacturer / TM Owner

Bracco Imaging S.P.A.

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Indications & Clinical Uses

  • Iomeron, an iodinated contrast agent, is used to improve visualization in imaging studies that involve vascular, joint, spinal, or cross‑sectional anatomy.
  • Angiography: provides enhanced vessel delineation for diagnostic and interventional procedures.
  • Arthrography: improves joint space contrast to assess cartilage and ligaments.
  • Myelography: increases contrast of the subarachnoid space for spinal imaging.
  • CT imaging: augments tissue differentiation in computed tomography scans.

How It Works

  • Iomeprol contains a high density of iodine atoms that absorb X‑ray photons, raising the radiodensity of blood, tissues, or cavities where it is administered. The resulting difference in attenuation between enhanced and non‑enhanced structures creates greater contrast on radiographic, CT, or fluoroscopic images, facilitating more accurate anatomical delineation.

Side Effects

Iomeron may cause a range of adverse reactions, from mild to severe, depending on patient sensitivity and administered volume.

Common Side Effects

  • Warm sensation or flushing at the injection site
  • Transient metallic taste in the mouth
  • Nausea or mild vomiting
  • Headache or mild dizziness

Serious or Rare Side Effects

  • Anaphylactic or severe allergic reaction
  • Acute renal impairment, especially in patients with pre‑existing kidney disease
  • Hypotension or cardiovascular collapse
  • Pulmonary edema or severe respiratory distress

Precautions & Warnings

  • Prior to using Iomeron, clinicians should evaluate patient risk factors and follow safe handling practices.
  • Assess renal function before administration: evaluate eGFR and consider hydration.
  • Screen for iodine allergy: avoid in patients with known hypersensitivity.
  • Use the lowest effective dose: tailor volume to the specific imaging requirement.
  • Monitor vital signs during injection: watch for hypotension or acute reactions.
  • Store at ambient temperature: keep below 25 °C, protect from light and moisture, retain in the original container.

Avoid Interactions

Iomeron can interact with other agents that affect renal function, thyroid status, or cardiovascular stability.

Major Interactions (Avoid)

  • Concurrent use of other iodinated contrast agents within 24 h: risk of cumulative iodine load.
  • Co‑administration with nephrotoxic drugs (e.g., aminoglycosides, NSAIDs): increased risk of renal injury.
  • Use with beta‑blockers: may mask contrast‑induced hypertension.

Moderate Interactions (Monitor Closely)

  • Thyroid hormone therapy: iodine load may alter thyroid function tests.
  • Diuretics: may affect renal clearance of the contrast medium.
  • Metformin in patients with impaired renal function: consider temporary discontinuation to prevent lactic acidosis.

Frequently Asked Questions

Iomeron is an iodinated contrast medium used to enhance the visibility of blood vessels, joints, the spinal canal, and soft tissues during imaging procedures such as angiography, arthrography, myelography, and computed tomography (CT) scans. By increasing radiodensity, it helps radiologists obtain clearer diagnostic images.

Iomeprol contains iodine atoms that strongly absorb X‑ray photons. When injected, the iodine increases the radiodensity of the area where it circulates, creating a contrast between enhanced structures and surrounding tissues. This differential attenuation allows imaging systems to produce sharper, more detailed pictures of anatomical features.

The specific dose of Iomeron is determined by the prescribing physician based on the type of imaging study, patient size, renal function, and clinical protocol. Healthcare professionals calculate the appropriate volume to achieve optimal contrast while minimizing risk.

The safety of Iomeron in pregnancy and lactation has not been definitively established. It should be used only if clearly needed and after careful risk‑benefit assessment by the treating physician. Breastfeeding mothers should discuss potential exposure with their healthcare provider.

To request Iomeron, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including any cold‑chain requirements), and necessary import documentation.

Iomeron (Iomeprol) is a low‑osmolar, non‑ionic iodinated contrast medium offering high iodine concentration (350 mg I/mL) and good tolerability. Compared with older high‑osmolar agents, it generally produces fewer discomfort reactions and a lower incidence of renal adverse effects, while providing comparable image quality.

Iomeron should be stored at ambient temperature, preferably below 25 °C, in its original sealed container. Protect the solution from direct sunlight, moisture, and extreme temperature fluctuations. Do not freeze or shake the vial before use.

Iomeron is supplied as a sterile solution for injection and is administered by a qualified healthcare professional via intraarterial, intraarticular, or intrathecal routes, depending on the imaging procedure. The injection is typically performed under aseptic conditions using appropriate catheters or needles.

The most serious risks include severe allergic reactions such as anaphylaxis, acute renal impairment especially in patients with pre‑existing kidney disease, hypotension or cardiovascular collapse, and rare pulmonary edema. Immediate medical attention is required if any of these events occur.

Iomeron should be avoided in patients with a known hypersensitivity to iodinated contrast media, those with uncontrolled severe asthma, or individuals with significant renal insufficiency where alternative imaging strategies are feasible. The prescribing clinician must evaluate each patient’s medical history before use.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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