Product image of Iomeron (Iomeprol) supplied by GNH India

Iomeron

Active Ingredient:
Iomeprol
Origin:
EU

Iomeron (Iomeprol)

Iomeprol, the active ingredient in Iomeron, is a non‑ionic iodinated contrast media presented as a sterile solution for injection for intra‑arterial, intra‑articular and intrathecal administration. It enhances X‑ray attenuation of extracellular fluids, allowing clear visualization of vascular, joint and spinal canal structures during diagnostic imaging procedures.

GNH India supplies Iomeron as a licensed, GDP‑compliant international pharmaceutical supplier, delivering the product to hospitals, diagnostic imaging centres, clinics and procurement teams worldwide under controlled conditions. Our distribution network ensures timely availability and compliance with local regulatory requirements.

Manufacturer / TM Owner

Bracco Imaging S.P.A.

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Indications & Clinical Uses

Iomeron (iomeprol) is an iodinated contrast agent employed in radiographic procedures that require enhanced visualization of vascular and fluid‑filled spaces.

  • Angiography: provides high‑contrast images of blood vessels to aid in the diagnosis of vascular diseases and guide interventional procedures.
  • Arthrography: improves delineation of joint spaces, facilitating assessment of cartilage, ligaments and intra‑articular pathology.
  • Myelography: enhances imaging of the spinal canal and nerve roots, supporting evaluation of spinal stenosis, disc herniation and tumors.
  • Other diagnostic imaging procedures requiring intra‑arterial, intra‑articular or intrathecal contrast: delivers reliable contrast enhancement for a variety of specialized studies.

How It Works

  • Iomeprol is a non‑ionic, water‑soluble iodine compound that, when injected, distributes within extracellular fluid compartments. The iodine atoms have a high atomic number, which increases X‑ray attenuation and produces a marked difference in radiodensity between the contrast‑enhanced structures and surrounding tissues. This physical property enables detailed visualization of vascular, joint and cerebrospinal fluid spaces during fluoroscopic, CT or digital subtraction imaging.

Side Effects

Iomeron may be associated with a range of adverse reactions, which are generally categorized by frequency and severity.

Common Side Effects

  • Warm sensation at injection site
  • Nausea or vomiting
  • Metallic taste in the mouth
  • Transient headache or flushing

Serious or Rare Side Effects

  • Severe allergic reaction including anaphylaxis
  • Acute renal impairment or contrast‑induced nephropathy
  • Significant hypotension or cardiovascular collapse
  • Pulmonary edema or respiratory distress

Precautions & Warnings

Prior to administering Iomeron, clinicians should observe several precautionary measures to minimize risk.

  • Assess renal function: evaluate eGFR or serum creatinine before use.
  • Review allergy history: identify previous reactions to iodinated contrast agents.
  • Use pre‑medication: consider antihistamines or steroids for patients with known sensitivity.
  • Ensure adequate hydration: encourage fluid intake before and after the procedure.
  • Store at ambient temperature: keep the solution in its original container, protect from light and moisture.

Avoid Interactions

Iomeron can interact with certain medications, requiring attention to avoid adverse outcomes.

Major Interactions (Avoid)

  • Metformin (high dose): concurrent use may increase risk of lactic acidosis in patients with impaired renal function.
  • Nephrotoxic drugs (e.g., aminoglycosides, NSAIDs): combined exposure can exacerbate renal injury.
  • Other iodine‑containing radiopharmaceuticals: cumulative iodine load may affect thyroid function.

Moderate Interactions (Monitor Closely)

  • Thyroid hormone therapy: iodine load may alter hormone levels, necessitating monitoring.
  • Diuretics: may influence fluid balance and affect contrast distribution.
  • ACE inhibitors or ARBs: potential for enhanced renal effects, especially in patients with pre‑existing kidney disease.

Frequently Asked Questions

Iomeron is an iodinated contrast medium used in diagnostic imaging procedures such as angiography, arthrography and myelography. It is injected intra‑arterially, intra‑articularly or intrathecally to enhance X‑ray attenuation, providing clearer images of blood vessels, joint spaces and the spinal canal for accurate clinical assessment.

Iomeprol contains iodine atoms with a high atomic number, which absorb X‑rays more effectively than surrounding tissues. After injection, it distributes in the extracellular fluid, increasing radiodensity of the targeted area. This contrast difference allows imaging systems to produce detailed pictures of vascular, joint and cerebrospinal fluid structures.

The dose of Iomeron is individualized by the prescribing physician based on the specific imaging study, patient weight, renal function and the required level of contrast enhancement. Dosage calculations follow established radiology guidelines and are adjusted to achieve optimal image quality while minimizing exposure.

The safety of Iomeron in pregnancy and lactation has not been definitively established. Because iodinated contrast agents cross the placenta and may be secreted in breast milk, it should only be used when clearly needed and after careful risk‑benefit assessment by the healthcare provider.

To order Iomeron, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including cold‑chain if required) and assistance with import documentation.

Iomeron is a non‑ionic, low‑osmolality iodinated contrast medium, which generally offers a lower incidence of adverse reactions compared with older high‑osmolality agents. Its physicochemical profile provides strong X‑ray attenuation and good tolerability, making it comparable to other modern agents such as iohexol or iopamidol for similar imaging indications.

Store Iomeron at ambient temperature, preferably below 25 °C. Keep the vial in its original packaging, protect it from direct light, moisture and extreme temperature fluctuations. Do not freeze the solution, and inspect the container for any signs of damage before use.

Iomeron is supplied as a sterile solution for injection and is administered by a qualified healthcare professional via intra‑arterial, intra‑articular or intrathecal routes, depending on the imaging study. The injection is performed under aseptic technique, and the volume is determined by the specific diagnostic protocol.

Serious risks include severe allergic reactions such as anaphylaxis, acute renal impairment (contrast‑induced nephropathy), significant hypotension or cardiovascular collapse, and pulmonary edema. Patients with known iodine allergy, compromised kidney function or severe cardiac disease should be closely monitored, and emergency measures must be readily available.

Iomeron should be avoided in patients with a documented severe hypersensitivity to iodinated contrast media, uncontrolled asthma, active renal failure (eGFR < 30 mL/min/1.73 m²), or in those who have experienced prior anaphylactic reactions to similar agents. The prescribing clinician must evaluate each case individually.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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