Product image of Iomeron (Iomeprol) supplied by GNH India

Iomeron

Active Ingredient:
Iomeprol
Origin:
EU

Iomeron (Iomeprol)

Iomeprol, the active ingredient in Iomeron, is a iodinated contrast media presented as a solution for injection for intraarterial, intrathecal and intravenous use. It enhances radiographic visualization of vascular and tissue structures during imaging procedures.

GNH India supplies Iomeron as a licensed, GDP-compliant international pharmaceutical supplier serving hospitals, imaging centres and clinics worldwide.

Manufacturer / TM Owner

Bracco Imaging Deutschland Gmbh

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Indications & Clinical Uses

  • Iomeron is an iodinated contrast agent used to improve image quality in vascular and tissue imaging procedures.
  • Angiography (cerebral, coronary, peripheral): provides enhanced visualization of blood vessels during diagnostic and interventional procedures.
  • CT imaging: increases contrast between soft tissues and blood, aiding detection of lesions and anatomical detail.
  • Myelography: delineates the spinal canal and nerve roots by highlighting cerebrospinal fluid spaces.
  • Contrast‑enhanced imaging of vascular structures: improves definition of arterial and venous anatomy for accurate assessment.

How It Works

  • Iomeprol is a high‑density, non‑ionic iodine compound that absorbs X‑rays more strongly than surrounding tissues. After injection into the vascular system or cerebrospinal fluid, it raises X‑ray attenuation, creating a contrast difference that highlights blood‑filled structures and organs, thereby allowing clearer radiographic and computed‑tomography images.

Side Effects

Iomeron may cause a range of reactions following injection.

Common Side Effects

  • Warmth or flushing sensation at the injection site.
  • Transient metallic taste in the mouth.
  • Mild nausea or vomiting.
  • Headache or dizziness.
  • Itching or mild urticaria.
  • Temporary increase in blood pressure.

Serious or Rare Side Effects

  • Severe allergic or anaphylactoid reaction, including bronchospasm.
  • Contrast‑induced nephropathy leading to acute kidney injury.
  • Hypotension or cardiovascular collapse.
  • Arrhythmias or cardiac arrest.
  • Seizures or neurologic disturbances.
  • Thyroid dysfunction due to iodine load.

Precautions & Warnings

  • When using Iomeron, clinicians should observe several safety measures.
  • Assess renal function: evaluate serum creatinine and eGFR before administration.
  • Review allergy history: identify prior reactions to iodinated contrast agents.
  • Use lowest effective dose: limit iodine exposure while achieving diagnostic quality.
  • Monitor vital signs: observe patients during and after injection for adverse reactions.
  • Avoid in patients with known severe iodine allergy: consider alternative imaging strategies.
  • Store at ambient temperature: keep below 25°C in the original container, protect from moisture and light.

Avoid Interactions

Iomeron can interact with other medications and substances that affect renal function or iodine handling.

Major Interactions (Avoid)

  • Metformin: risk of lactic acidosis in patients with impaired renal function.
  • Concurrent nephrotoxic drugs (e.g., aminoglycosides, NSAIDs): may exacerbate renal injury.
  • Other iodine‑containing radiopharmaceuticals: cumulative iodine load can increase toxicity.

Moderate Interactions (Monitor Closely)

  • Loop diuretics: may alter renal clearance of the contrast agent.
  • ACE inhibitors or ARBs: potential for additive effects on renal function.
  • Thyroid hormone therapy: iodine load may interfere with thyroid hormone balance.

Frequently Asked Questions

Iomeron is a brand name for the iodinated contrast agent iomeprol, used to enhance the visibility of blood vessels and internal structures during imaging procedures such as angiography, computed tomography (CT) scans, and myelography. It is administered by injection and helps radiologists obtain clearer diagnostic images.

Iomeprol is a high‑density, non‑ionic iodine compound that absorbs X‑rays more strongly than surrounding tissues. When injected into the vascular system or cerebrospinal fluid, it increases X‑ray attenuation, creating a contrast between blood‑filled structures and adjacent organs, thereby improving the delineation of vessels, organs, and pathological lesions on radiographic images.

The specific dose of Iomeron is determined by the prescribing physician based on the type of imaging study, patient weight, renal function, and the required level of contrast enhancement. Dosing guidelines are provided in the product’s prescribing information and must be individualized for each patient.

Safety data for iomeprol in pregnancy and lactation are limited, and the product is generally classified as contraindicated or to be used only if the potential diagnostic benefit outweighs the possible risk to the fetus or infant. Healthcare providers should evaluate the risk‑benefit profile before administering Iomeron to pregnant or nursing patients.

To place an order, submit an enquiry on the Iomeron product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including any cold‑chain requirements), and necessary import documentation.

Iomeron (iomeprol) is a non‑ionic, low‑osmolality iodinated contrast medium, offering a favorable safety profile compared with older high‑osmolality agents that are associated with higher rates of discomfort and adverse reactions. Compared with other low‑osmolality agents, its physicochemical properties are similar, and choice often depends on institutional preference, cost, and specific imaging protocols.

Iomeron should be stored at controlled room temperature, preferably below 25 °C, in its original sealed container. Protect the solution from direct sunlight, moisture, and freezing. Before use, inspect the vial for particulate matter or discoloration and allow the solution to reach room temperature if it has been refrigerated during transport.

Iomeron is supplied as a sterile solution for injection and is administered intravenously, intra‑arterially, or intrathecally by a qualified healthcare professional. The injection is typically performed using a power injector or manual bolus, following aseptic technique and the dosing instructions provided in the prescribing information.

The most serious risks include severe allergic or anaphylactoid reactions, contrast‑induced nephropathy leading to acute kidney injury, and hemodynamic changes such as hypotension or arrhythmias. Patients with known iodine allergy, impaired renal function, or uncontrolled thyroid disease should be closely monitored, and emergency measures must be readily available.

Iomeron is contraindicated in patients with a documented severe hypersensitivity to iomeprol or any iodinated contrast media, as well as in individuals with uncontrolled hyperthyroidism where an iodine load could exacerbate the condition. Caution is also advised for patients with severe renal impairment, as the agent is eliminated renally.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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