Product image of Iomeron (Iomeprol) supplied by GNH India

Iomeron

Active Ingredient:
Iomeprol
Origin:
EU

Iomeron (Iomeprol)

Iomeprol, the active ingredient in Iomeron, is an iodinated contrast media presented as a 300 mg I/mL solution for injection for intraarterial, intrathecal, and intravenous use. It enhances radiographic visualization of vascular and tissue structures during imaging procedures in patients requiring diagnostic angiography, CT scans, myelography, or cerebral angiography.

GNH India supplies Iomeron as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Bracco Uk Ltd

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Indications & Clinical Uses

  • Iomeron, an iodinated contrast agent, improves X‑ray based imaging of vascular and tissue structures.
  • Angiography: provides enhanced visualization of blood vessels for diagnostic and interventional procedures.
  • Computed tomography (CT) imaging: increases contrast between tissues, yielding clearer cross‑sectional images.
  • Myelography: delineates the spinal canal and nerve roots with greater detail.
  • Cerebral angiography: improves definition of cerebral vasculature for accurate assessment.

How It Works

  • Iomeprol contains a high concentration of iodine atoms that strongly absorb X‑ray photons. After intravenous, intra‑arterial, or intrathecal administration, the agent distributes within the extracellular fluid, raising the radiodensity of blood and tissues. This increased attenuation creates a contrast differential between vascular structures and surrounding tissues, allowing clearer delineation on radiographic, CT, and myelographic images.

Side Effects

Iomeron may cause a range of adverse reactions, most of which are mild and transient.

Common Side Effects

  • Warm sensation or flushing at the injection site
  • Nausea or vomiting
  • Mild headache
  • Metallic taste in the mouth
  • Transient urticaria or itching
  • Mild hypotension

Serious or Rare Side Effects

  • Anaphylactic or severe allergic reaction
  • Acute kidney injury, especially in patients with pre‑existing renal impairment
  • Seizures or neurological disturbances
  • Cardiac arrhythmias or severe hypotension
  • Pulmonary edema
  • Thyroid dysfunction due to iodine load

Precautions & Warnings

  • Before administering Iomeron, clinicians should evaluate patient risk factors and monitor for adverse events.
  • Renal function assessment: evaluate serum creatinine and eGFR, especially in patients with known kidney disease.
  • Allergy history: screen for prior reactions to iodinated contrast or other allergens.
  • Thyroid status: consider risk of iodine‑induced thyroid dysfunction in patients with hyperthyroidism.
  • Pregnancy considerations: use only if clearly needed, as the agent is category B.
  • Concurrent nephrotoxic drugs: avoid or adjust dosing when patients are receiving aminoglycosides, NSAIDs, or other renal‑impacting agents.
  • Store below 25°C: keep in original packaging, protect from light and moisture.

Avoid Interactions

Iomeron can interact with other substances that affect renal function or iodine load.

Major Interactions (Avoid)

  • Concurrent use of other iodinated contrast agents: cumulative iodine may increase toxicity.
  • Nephrotoxic medications (e.g., aminoglycosides, high‑dose NSAIDs): heightened risk of renal impairment.
  • Metformin in patients with reduced renal function: risk of lactic acidosis; consider temporary discontinuation.

Moderate Interactions (Monitor Closely)

  • Thyroid hormone therapy: monitor thyroid function tests due to iodine load.
  • Diuretics: may exacerbate volume depletion and renal effects; adjust fluid management.
  • Anticoagulants during intrathecal administration: increased bleeding risk; monitor coagulation parameters.

Frequently Asked Questions

Iomeron is an iodinated contrast medium used to enhance X‑ray based imaging studies such as angiography, computed tomography (CT), myelography, and cerebral angiography. By increasing the radiodensity of blood and extracellular fluid, it helps clinicians obtain clearer images of vascular and tissue structures during diagnostic and interventional procedures.

Iomeprol contains iodine atoms that strongly absorb X‑ray photons. After injection, it distributes in the extracellular space, raising the attenuation of X‑rays in blood and tissues. This creates a contrast difference between vessels or organs and surrounding structures, allowing more detailed visualization on radiographic, CT, and myelographic images.

The specific dose of Iomeron is determined by the prescribing physician based on the type of imaging study, patient weight, renal function, and clinical protocol. Dosage calculations are individualized and should follow the recommendations of the imaging department and the product’s prescribing information.

Iomeron is classified as pregnancy category B, indicating that animal studies have not shown risk to the fetus and there are no adequate human studies. It should be used only if clearly needed. Limited data are available for breastfeeding; the decision to continue nursing should be made by the healthcare provider after weighing benefits and risks.

To order Iomeron, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India supplies hospitals, pharmacies, and procurement teams worldwide. After receiving the request, the sales team will verify trade or institutional credentials, then provide pricing, availability, shipping details (including any cold‑chain requirements), and assist with import documentation.

Iomeron (iomeprol) is a non‑ionic, low‑osmolality iodinated contrast medium, offering a favorable safety profile compared with older high‑osmolality agents. Compared with other low‑osmolality agents, it provides comparable image quality while reducing the incidence of discomfort and adverse reactions. Choice of agent often depends on specific imaging requirements, patient risk factors, and institutional preferences.

Iomeron should be stored below 25 °C in its original container, protected from light and moisture. Do not freeze the solution. Before use, inspect the vial for particulate matter or discoloration. Handle with aseptic technique and avoid shaking the vial to maintain solution integrity.

Iomeron is administered as a sterile solution for injection via intra‑arterial, intravenous, or intrathecal routes, depending on the imaging procedure. The injection rate and volume are determined by the imaging protocol and patient characteristics. Administration should be performed by qualified healthcare professionals in a setting equipped for monitoring and emergency management.

The most serious risks include severe allergic reactions such as anaphylaxis, acute kidney injury especially in patients with pre‑existing renal impairment, and thyroid dysfunction due to iodine load. Prompt recognition and management of these events are essential, and patients at risk should be identified before administration.

Iomeron should be avoided in patients with a known hypersensitivity to iodinated contrast media, those with uncontrolled hyperthyroidism, and individuals with severe renal impairment where alternative imaging methods are feasible. Caution is also advised for patients on metformin with reduced kidney function, and for pregnant or breastfeeding women unless the diagnostic benefit outweighs potential risks.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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