Product image of Iomeron (Iomeprol) supplied by GNH India

Iomeron

Active Ingredient:
Iomeprol
Origin:
EU

Iomeron (Iomeprol)

Iomeprol, the active ingredient in Iomeron, is an iodinated non‑ionic contrast agent presented as a sterile solution for injection for intra‑arterial and intravenous use. It increases X‑ray attenuation of blood and tissues, providing high‑density iodine atoms that improve visualization of vascular structures during diagnostic imaging procedures.

GNH India supplies Iomeron as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, diagnostic centres and clinics worldwide with reliable access to EU‑origin contrast media.

Manufacturer / TM Owner

Bracco Imaging S.P.A.

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Indications & Clinical Uses

Iomeron, an iodinated non‑ionic contrast agent, is used in radiographic imaging to enhance vascular and tissue visualization.

  • Angiography: Improves delineation of arterial and venous structures during catheter‑based imaging.
  • Computed tomography (CT) imaging: Provides high‑contrast enhancement of organs and vessels for detailed cross‑sectional images.
  • Vascular imaging procedures: Facilitates clear visualization of blood flow and vessel anatomy in both intra‑arterial and intravenous studies.

How It Works

  • Iomeprol contains a high concentration of iodine atoms that absorb X‑ray photons. After intravenous or intra‑arterial injection, the agent distributes in the extracellular fluid and remains within the vascular compartment, increasing the attenuation of X‑rays in blood and tissues. This heightened attenuation creates contrast between structures, allowing radiologists to visualize vessels and organ perfusion more clearly during imaging examinations.

Side Effects

Iomeron may be associated with a range of adverse reactions following intravascular administration.

Common Side Effects

  • Warmth or flushing sensation at the injection site.
  • Metallic taste in the mouth.
  • Nausea or mild vomiting.
  • Headache.
  • Transient urticaria or mild skin rash.
  • Mild hypotension.

Serious or Rare Side Effects

  • Severe allergic reaction or anaphylaxis.
  • Acute renal impairment, especially in patients with pre‑existing kidney disease.
  • Persistent hypotension or cardiovascular collapse.
  • Cardiac arrhythmias.
  • Seizures.
  • Pulmonary edema.

Precautions & Warnings

Prior to administration, clinicians should evaluate patient risk factors and follow appropriate safety measures.

  • Renal function assessment: Verify baseline creatinine or eGFR to minimize contrast‑induced nephropathy.
  • Allergy screening: Identify any known iodine or contrast media hypersensitivity.
  • Thyroid monitoring: Use caution in patients with hyperthyroidism or thyroid disorders.
  • Hydration: Ensure adequate patient hydration before and after the procedure.
  • Store at ambient temperature: Keep in original container, protect from moisture and direct light.

Avoid Interactions

Iomeron can interact with other medications or agents that affect renal function or iodine handling.

Major Interactions (Avoid)

  • Concurrent administration of other iodinated contrast media: Increases risk of iodine overload.
  • Nephrotoxic drugs (e.g., aminoglycosides, amphotericin B, high‑dose NSAIDs): May exacerbate renal dysfunction.
  • Radioactive iodine therapy: May interfere with iodine uptake and therapeutic efficacy.

Moderate Interactions (Monitor Closely)

  • Diuretics: May alter fluid balance and affect contrast distribution.
  • ACE inhibitors or ARBs: May increase risk of contrast‑induced nephropathy; consider temporary discontinuation.
  • Anticoagulants: May raise the risk of bleeding at the injection site.

Frequently Asked Questions

Iomeron is an iodinated non‑ionic contrast agent used to enhance X‑ray based imaging studies such as angiography, computed tomography (CT) scans, and other vascular imaging procedures. By increasing the attenuation of X‑rays in blood and tissues, it improves the visibility of vascular structures and organ perfusion, aiding accurate diagnosis.

Iomeprol contains iodine atoms with a high atomic number that absorb X‑ray photons. After injection, it distributes within the vascular and extracellular spaces, raising the X‑ray attenuation of blood and tissues. This creates a contrast difference between vessels and surrounding structures, allowing clearer radiographic images.

The dose of Iomeron is determined by the prescribing physician based on the specific imaging study, patient weight, renal function, and clinical protocol. Dosage calculations are individualized and should follow the recommendations of the imaging department and relevant regulatory guidelines.

The safety of Iomeron in pregnancy or while breastfeeding has not been definitively established. Use is generally avoided unless the diagnostic benefit outweighs potential risk. Clinicians should assess each case carefully and consider alternative imaging methods when possible.

To order Iomeron, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India supplies hospitals, pharmacies and procurement teams worldwide, and will request verification of trade or institutional credentials. The sales team will then respond with pricing, availability, shipping details (including any cold‑chain requirements) and required import documentation.

Iomeron is a non‑ionic, low‑osmolality iodinated contrast medium, offering a favorable safety profile compared with older high‑osmolality agents. Compared with other non‑ionic agents, it provides similar image quality while potentially reducing the incidence of adverse reactions, especially in patients with mild renal impairment.

Iomeron should be stored at ambient temperature, preferably below 25 °C, in its original packaging. Protect the solution from direct sunlight, moisture and extreme temperature fluctuations. Do not freeze or shake the vial before use.

Iomeron is administered as a sterile solution for injection via the intra‑arterial or intravenous route. The injection is performed by qualified healthcare professionals under imaging guidance, using the dosage and injection rate recommended for the specific diagnostic procedure.

The most serious risks include severe allergic reactions such as anaphylaxis, acute renal impairment especially in patients with pre‑existing kidney disease, and cardiovascular events like hypotension or arrhythmias. Prompt recognition and management of these reactions are essential.

Iomeron should be avoided in patients with a known hypersensitivity to iodinated contrast media, severe uncontrolled hyperthyroidism, or those with critically impaired renal function where alternative imaging methods are feasible. Clinicians must evaluate individual risk factors before administration.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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