Product image of Iomeron (Iomeprol) supplied by GNH India

Iomeron

Active Ingredient:
Iomeprol
Origin:
EU

Iomeron (Iomeprol)

Iomeprol, the active ingredient in Iomeron, is an iodinated contrast media presented as a solution for injection for intra‑arterial and intravenous use. It enhances X‑ray attenuation during imaging procedures, allowing clearer visualization of vascular structures and organs in patients undergoing diagnostic radiology and therapeutic planning.

GNH India supplies Iomeron as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, clinics, imaging centres and research institutions worldwide, adhering to stringent quality standards and providing full regulatory documentation for export to EU and other markets.

Manufacturer / TM Owner

Bracco Imaging Deutschland Gmbh

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Indications & Clinical Uses

Iomeron is used as an iodinated contrast agent to improve radiographic visualization in various imaging procedures.

  • Angiography: enhances visualization of blood vessels for diagnostic and interventional procedures.
  • Computed tomography (CT) imaging: provides high‑contrast detail of soft tissues and organs.
  • Myelography: improves delineation of the spinal canal and nerve roots.
  • Urography: highlights urinary tract structures for functional assessment.
  • Contrast‑enhanced radiographic procedures: facilitates clearer imaging in a range of X‑ray based studies.

How It Works

  • Iomeprol contains a high concentration of iodine atoms that absorb X‑ray photons more effectively than surrounding tissues. After intravenous or intra‑arterial injection, the solution distributes within the vascular and extracellular compartments, increasing the attenuation coefficient of blood and organs. This heightened attenuation creates a stark contrast between structures on radiographic images, enabling clinicians to differentiate anatomical details and pathological changes with greater accuracy.

Side Effects

Iomeron may be associated with a range of adverse reactions, from mild to severe.

Common Side Effects

  • Warmth or flushing sensation at the injection site.
  • Metallic taste in the mouth.
  • Nausea or vomiting.
  • Transient urticaria or itching.

Serious or Rare Side Effects

  • Anaphylactoid or severe allergic reaction, including bronchospasm.
  • Acute kidney injury, particularly in patients with pre‑existing renal dysfunction.
  • Thyroid dysfunction such as hyper‑ or hypothyroidism.

Precautions & Warnings

Prior to administration, several safety measures should be considered.

  • Assess renal function: evaluate serum creatinine and eGFR before administration.
  • Screen for iodine or contrast allergy: obtain detailed allergy history.
  • Ensure adequate hydration: encourage fluid intake pre‑ and post‑procedure.
  • Use the lowest effective dose: tailor volume to imaging requirement.
  • Monitor thyroid status: consider thyroid function tests in at‑risk patients.
  • Store at ambient temperature: keep in original packaging, protect from light and moisture.

Avoid Interactions

Iomeron can interact with certain medications, requiring attention to avoid or monitor effects.

Major Interactions (Avoid)

  • Metformin: concurrent use may increase risk of lactic acidosis in renal impairment.
  • Nephrotoxic agents (e.g., aminoglycosides, high‑dose NSAIDs): may exacerbate contrast‑induced nephropathy.
  • Thyroid hormone therapy: iodinated contrast can alter thyroid hormone levels.

Moderate Interactions (Monitor Closely)

  • Diuretics: may affect fluid balance and renal clearance of contrast.
  • ACE inhibitors or ARBs: monitor blood pressure and renal function during contrast administration.
  • Beta‑blockers: may mask signs of anaphylactoid reactions.

Frequently Asked Questions

Iomeron is an iodinated contrast agent employed during radiographic examinations such as angiography, computed tomography (CT), myelography, urography, and other contrast‑enhanced imaging studies. It improves the visibility of blood vessels, organs, and tissue structures, aiding accurate diagnosis and procedural guidance.

Iomeprol contains a high density of iodine atoms that absorb X‑ray photons more efficiently than surrounding tissues. When injected, it circulates through the vascular system, increasing X‑ray attenuation of blood and extracellular spaces, which creates a pronounced contrast on the resulting images.

The dose of Iomeron is individualized by the prescribing physician based on the specific imaging modality, the anatomical area to be examined, patient weight, and renal function. No fixed regimen is provided; the healthcare professional calculates the appropriate volume for each procedure.

The safety of Iomeron in pregnancy and lactation has not been definitively established. Because iodinated contrast agents cross the placenta and may be secreted in breast milk, clinicians should weigh potential benefits against risks and consider alternative imaging strategies when possible.

To order Iomeron, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India supplies hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including any cold‑chain requirements) and necessary import documentation.

Iomeron (Iomeprol) is a low‑osmolality, non‑ionic iodinated contrast medium, offering a favorable safety profile compared with high‑osmolality agents. Its iodine concentration provides strong X‑ray attenuation while reducing the incidence of discomfort and adverse reactions relative to older ionic formulations.

Iomeron should be stored at ambient temperature, below 25 °C, in its original container. Protect the solution from direct sunlight, excessive heat and moisture. Do not freeze the product, and avoid vigorous shaking before use to maintain solution integrity.

Iomeron is administered by a trained healthcare professional as an intravenous or intra‑arterial injection. The solution is typically delivered through a peripheral or central venous line, using a power injector or manual bolus, according to the imaging protocol prescribed by the radiologist.

Serious risks include anaphylactoid reactions such as severe allergy or bronchospasm, contrast‑induced acute kidney injury, and thyroid dysfunction due to iodine load. Prompt recognition and management of these events are essential, especially in patients with known renal impairment or thyroid disease.

Iomeron is contraindicated in patients with a documented severe allergy to iodinated contrast media, those with uncontrolled hyperthyroidism, and individuals with a history of severe renal insufficiency where alternative imaging methods are feasible. Clinical judgment should guide use in all other cases.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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