Product image of Iomeron (Iomeprol) supplied by GNH India

Iomeron

Active Ingredient:
Iomeprol
Origin:
EU

Iomeron (Iomeprol)

Iomeprol, the active ingredient in Iomeron, is an iodinated contrast media presented as a solution for injection for intra‑arterial and intravenous use. It enhances radiographic visualization during diagnostic imaging procedures in patients undergoing angiography, computed tomography, urography or venography.

GNH India supplies Iomeron as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals worldwide. The company adheres to global quality standards and provides reliable logistics for clinical and imaging centres across multiple regions. Customers benefit from consistent product availability and regulatory support for cross‑border procurement.

Manufacturer / TM Owner

Bracco Imaging S.P.A.

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Indications & Clinical Uses

Iomeron is an iodinated contrast agent used in radiographic imaging procedures to improve visualization of vascular and organ structures.

  • Angiography: provides enhanced vessel delineation for diagnostic and interventional procedures.
  • Computed tomography (CT) imaging: increases tissue contrast to aid detection of lesions and anatomical detail.
  • Urography: highlights urinary tract anatomy for assessment of kidneys, ureters and bladder.
  • Venography: improves visualization of venous structures for evaluation of thrombosis or malformations.

How It Works

  • Iomeprol contains a high concentration of iodine atoms that absorb X‑ray photons. When administered intravenously or intra‑arterially, the iodine molecules distribute within the vascular and extracellular compartments, attenuating the X‑ray beam and creating a temporary difference in radiodensity between blood‑filled structures and surrounding tissues. This contrast enhancement allows radiologists to distinguish anatomical details and pathological changes on imaging studies.

Side Effects

Iomeron may be associated with a range of adverse reactions, varying from mild and transient to severe and potentially life‑threatening.

Common Side Effects

  • Warmth or flushing sensation during injection.
  • Metallic taste or transient dysgeusia.
  • Nausea or mild vomiting.
  • Headache or dizziness.

Serious or Rare Side Effects

  • Acute allergic or anaphylactoid reactions, including urticaria and bronchospasm.
  • Contrast‑induced nephropathy causing renal impairment.
  • Severe hypotension or cardiovascular collapse.

Precautions & Warnings

Prior to administering Iomeron, clinicians should observe several safety measures to minimize risk and ensure optimal imaging outcomes.

  • Assess renal function: evaluate serum creatinine and eGFR before use.
  • Screen for iodine or contrast allergy: obtain detailed allergy history.
  • Use lowest effective dose: tailor volume to specific imaging protocol.
  • Monitor vital signs: observe patient during and after injection for reactions.
  • Avoid in patients with uncontrolled hyperthyroidism: high iodine load may exacerbate condition.
  • Store at ambient temperature: keep in original container, protect from moisture and light.

Avoid Interactions

Iomeron can interact with certain medicines, influencing safety or efficacy of the contrast procedure.

Major Interactions (Avoid)

  • Metformin: risk of lactic acidosis if renal function declines after contrast exposure.
  • Thyroid hormone therapy or radioactive iodine: excess iodine may disrupt thyroid function.
  • Nephrotoxic agents (e.g., aminoglycosides, amphotericin B): combined use increases risk of renal injury.

Moderate Interactions (Monitor Closely)

  • NSAIDs: may impair renal perfusion, heightening contrast‑induced nephropathy risk.
  • Loop diuretics: can affect fluid balance and renal clearance of iodine.
  • Beta‑blockers: may mask signs of contrast‑related hypotension.

Frequently Asked Questions

Iomeron is a radiographic contrast agent containing iomeprol, employed to enhance the visibility of blood vessels and organ structures during imaging examinations such as angiography, computed tomography (CT), urography and venography. By increasing the attenuation of X‑ray beams, it helps radiologists detect abnormalities and plan interventions.

Iomeprol is a high‑iodine compound; each molecule carries several iodine atoms that strongly absorb X‑ray photons. After intravenous or intra‑arterial injection, the iodine distributes within the vascular and extracellular spaces, temporarily raising the radiodensity of those areas. This contrast difference allows imaging systems to differentiate tissues and vascular structures more clearly.

The dose of Iomeron is determined by the prescribing physician based on the specific imaging study, patient weight, renal function and the required level of contrast enhancement. Dosing guidelines are provided in the product’s prescribing information, and the healthcare professional selects the appropriate volume for each procedure.

The safety of Iomeron during pregnancy and lactation has not been definitively established. Iodinated contrast agents cross the placenta and may affect fetal thyroid function, and small amounts can be excreted in breast milk. Use is generally reserved for situations where the diagnostic benefit outweighs potential risks, and clinicians should consult current guidelines.

To place an order, visit the product page on gnhindia.com, enter the desired quantity of Iomeron, and submit the enquiry form. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details—including any required cold‑chain handling—and assists with import documentation.

Iomeron (iomeprol) is a non‑ionic, low‑osmolality iodinated contrast medium, offering a favorable safety profile compared with older high‑osmolality agents that were associated with higher rates of adverse reactions. Compared with other low‑osmolality agents, its iodine concentration and viscosity are similar, providing comparable image quality while reducing the risk of discomfort and renal effects.

Iomeron should be stored at controlled room temperature, below 25 °C, in its original sealed container. Protect the solution from direct sunlight, moisture and extreme temperatures. Before use, inspect the vial for particulate matter or discoloration, and avoid shaking the product vigorously. Follow standard aseptic techniques when preparing the injection.

Iomeron is supplied as a sterile solution for injection and is administered intravenously or intra‑arterially by a qualified healthcare professional. The injection is typically performed using a power injector or manual bolus, following the imaging protocol’s recommended volume and rate. Proper catheter placement and patient monitoring are essential during administration.

The most serious risks include acute allergic or anaphylactoid reactions, which can manifest as urticaria, bronchospasm or cardiovascular collapse, and contrast‑induced nephropathy leading to acute kidney injury, especially in patients with pre‑existing renal impairment. Severe hypotension and cardiac arrhythmias may also occur, requiring immediate medical intervention.

Iomeron is contraindicated in patients with a known hypersensitivity to iomeprol or any iodinated contrast media, as well as those with uncontrolled hyperthyroidism where excess iodine could exacerbate the condition. Caution is advised in individuals with severe renal insufficiency, recent use of nephrotoxic drugs, or those who are pregnant or breastfeeding unless the diagnostic benefit justifies the potential risk.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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