Product image of Iomeron (Iomeprol) supplied by GNH India

Iomeron

Active Ingredient:
Iomeprol
Origin:
EU

Iomeron (Iomeprol)

Iomeprol, the active ingredient in Iomeron, is an iodinated contrast media presented as a solution for injection for intraarterial and intravenous use. It provides radiodense contrast for diagnostic imaging procedures such as angiography, CT imaging, and vascular imaging.

GNH India supplies Iomeron as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, imaging centres and clinics worldwide. The company adheres to stringent quality standards and provides regulatory documentation for global distribution.

Manufacturer / TM Owner

Bracco Imaging S.P.A.

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Indications & Clinical Uses

  • Iomeron is an iodinated contrast agent used in radiographic procedures that require enhanced visualization of vascular and tissue structures.
  • Angiography: improves delineation of blood vessels for diagnostic and interventional procedures.
  • CT imaging: enhances contrast between organs and vasculature, facilitating accurate interpretation of computed tomography scans.
  • Vascular imaging: enables detailed assessment of arterial and venous anatomy during specialized imaging studies.

How It Works

  • Iomeprol contains multiple iodine atoms that possess a high atomic number, which strongly attenuates X‑ray photons. After intravenous or intra‑arterial injection, the iodine‑rich solution distributes within the vascular and extracellular spaces, increasing radiodensity of blood and perfused tissues. This heightened X‑ray absorption creates a contrast between vessels or organs and surrounding structures, allowing clearer radiographic images for diagnostic evaluation.

Side Effects

Iomeron may cause a range of reactions following administration.

Common Side Effects

  • Warmth or flushing sensation during injection.
  • Metallic or salty taste in the mouth.
  • Mild nausea or vomiting.
  • Headache or dizziness.
  • Transient itching or urticaria.
  • Temporary mild hypotension.

Serious or Rare Side Effects

  • Severe allergic reaction (anaphylaxis) requiring emergency treatment.
  • Contrast‑induced nephropathy leading to acute kidney injury.
  • Significant hypotension or cardiovascular collapse.
  • Cardiac arrhythmias in susceptible patients.
  • Pulmonary edema or respiratory distress.
  • Thyroid dysfunction due to iodine load.

Precautions & Warnings

  • Before using Iomeron, clinicians should consider several safety measures.
  • Assess renal function: evaluate eGFR or serum creatinine to identify patients at risk of contrast‑induced nephropathy.
  • Screen for iodine allergy: obtain a detailed history of prior contrast reactions or iodine sensitivity.
  • Hydration: ensure adequate fluid intake before and after the procedure to support renal clearance.
  • Use lowest effective dose: tailor volume and concentration to the specific imaging protocol.
  • Monitor vital signs: observe patients during and after injection for immediate adverse reactions.
  • Store at ambient temperature: keep in original container, protect from light and moisture, and do not freeze.

Avoid Interactions

Iomeron can interact with other agents that affect iodine load or renal function.

Major Interactions (Avoid)

  • Concurrent use of other iodinated contrast agents, which may increase total iodine exposure.
  • High‑dose iodine‑containing medications (e.g., amiodarone) that can compound iodine burden.
  • Nephrotoxic drugs such as aminoglycosides or high‑dose NSAIDs, which may exacerbate renal injury.

Moderate Interactions (Monitor Closely)

  • Diuretics, which can alter fluid balance and affect contrast clearance.
  • Metformin in patients with reduced renal function, due to risk of lactic acidosis.
  • Beta‑blockers, which may mask hypotensive responses after contrast administration.

Frequently Asked Questions

Iomeron is a sterile solution of iomeprol used as an iodinated contrast medium in diagnostic imaging. It is administered intravenously or intra‑arterially to enhance visualization of blood vessels and organ structures during procedures such as angiography, computed tomography (CT) scans, and other vascular imaging studies. The contrast improves differentiation between tissues, helping radiologists obtain clearer images for accurate diagnosis.

Iomeprol contains iodine atoms that have a high atomic number, which strongly attenuates X‑ray photons. When injected, the iodine‑rich solution distributes within the vascular and extracellular compartments, increasing radiodensity of blood and perfused tissues. This heightened absorption of X‑rays creates a contrast between vessels or organs and surrounding structures on radiographic images, allowing detailed assessment of anatomy and pathology.

The dose of Iomeron is determined by the prescribing physician based on the specific imaging protocol, patient weight, renal function, and the anatomical area to be examined. The healthcare professional calculates the appropriate volume and concentration to achieve optimal image quality while minimizing exposure. Dosage information is provided in the product’s prescribing information and must be individualized for each patient.

The safety of iomeprol during pregnancy or lactation has not been fully established, and it is classified as a category where benefits must outweigh potential risks. Use is generally avoided unless the diagnostic information is essential for maternal or fetal health. Breastfeeding mothers should consult their physician; if administered, the infant may be monitored, and temporary cessation of nursing can be considered based on clinical judgment.

To place an order, visit the product page for Iomeron on the GNH India website (gnhindia.com) and submit an enquiry with the required quantity and intended use. GNH India works with hospitals, pharmacies, and procurement teams worldwide, verifying trade or institutional credentials before providing a formal quotation, confirming availability, shipping terms (including cold‑chain if required), and necessary import documentation.

Iomeron (iomeprol) is a non‑ionic, low‑osmolality iodinated contrast medium, offering a favorable safety profile compared with older high‑osmolality agents. Its physicochemical properties provide high image quality with reduced incidence of discomfort and adverse reactions. Compared with other low‑osmolality agents, differences are mainly in iodine concentration, viscosity, and specific approved indications, which the prescribing clinician evaluates for each imaging study.

Iomeron should be stored at controlled room temperature, typically below 25 °C, in its original sealed container. The solution must be protected from direct sunlight and moisture. Do not freeze or shake the vial; gently invert if mixing is required. Prior to use, inspect the container for particulate matter or discoloration, and ensure the product is within its expiry date.

Iomeron is supplied as a sterile aqueous solution for injection and is administered by a qualified healthcare professional either intravenously (IV) or intra‑arterially (IA) depending on the imaging procedure. The injection is performed using a suitable catheter or IV line, with the volume and rate adjusted to the protocol. Proper aseptic technique and patient monitoring are essential throughout the administration.

The most serious adverse events linked to iodinated contrast media like Iomeron include severe allergic reactions such as anaphylaxis, contrast‑induced nephropathy leading to acute kidney injury, and significant hypotension or cardiac arrhythmias in susceptible patients. Prompt recognition and immediate medical intervention are critical. Patients with known iodine allergy, impaired renal function, or unstable cardiovascular status require careful assessment before use.

Iomeron is contraindicated in patients with a documented hypersensitivity to iomeprol or any component of the formulation, as well as in individuals with a history of severe reactions to iodinated contrast agents. Caution is advised, and alternative imaging strategies should be considered for patients with uncontrolled asthma, severe renal impairment, or active thyroid disease that could be exacerbated by iodine exposure.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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