Product image of Iomeron (Iomeprol) supplied by GNH India

Iomeron

Active Ingredient:
Iomeprol
Origin:
EU

Iomeron (Iomeprol)

Iomeprol, the active ingredient in Iomeron, is an iodinated contrast media presented as a solution for injection for intra‑arterial and intravenous use. It enhances X‑ray imaging by increasing attenuation, aiding procedures such as angiography, CT scans and vascular imaging.
GNH India supplies Iomeron as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals worldwide.

Manufacturer / TM Owner

Bracco Imaging S.P.A.

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Indications & Clinical Uses

Iomeron is an iodinated contrast agent used in radiographic procedures that require enhanced vascular and tissue visualization.

  • Angiography: improves delineation of blood vessels for diagnostic and interventional procedures.
  • Computed tomography (CT) imaging: increases contrast between structures, facilitating accurate interpretation.
  • Vascular imaging: highlights arterial and venous anatomy to support clinical decision‑making.

How It Works

  • Iomeprol is a non‑ionic, low‑osmolar iodinated contrast agent. Its iodine atoms strongly absorb X‑ray photons, raising attenuation of the vascular compartment and surrounding tissues. After intravenous or intra‑arterial injection, the agent distributes rapidly within the bloodstream, providing temporary contrast that enhances image quality, and is eliminated unchanged by renal excretion.

Side Effects

Iomeron may cause a range of reactions following administration.

Common Side Effects

  • Warm sensation or flushing at the injection site
  • Nausea or vomiting
  • Mild headache
  • Metallic taste in the mouth
  • Transient urticaria or itching
  • Mild, temporary hypotension

Serious or Rare Side Effects

  • Anaphylactic or severe allergic reaction
  • Acute kidney injury (contrast‑induced nephropathy)
  • Severe hypotension or cardiovascular collapse
  • Pulmonary edema or respiratory distress
  • Cardiac arrhythmias
  • Neurological events such as seizures

Precautions & Warnings

Prior to using Iomeron, several safety measures should be observed.

  • Assess renal function: evaluate creatinine clearance to reduce nephrotoxicity risk.
  • Screen for iodine allergy: obtain detailed allergy history and consider pre‑medication if needed.
  • Monitor vital signs: observe blood pressure and heart rate during and after injection.
  • Avoid in uncontrolled hyperthyroidism: iodine load may exacerbate thyroid activity.
  • Use lowest effective dose: tailor volume to imaging requirements and patient size.
  • Store at 2-8°C: keep refrigerated, protect from light, do not freeze or shake.

Avoid Interactions

Iomeron can interact with several medications, requiring careful management.

Major Interactions (Avoid)

  • Metformin: risk of lactic acidosis in renal impairment; consider temporary discontinuation.
  • NSAIDs or other nephrotoxic drugs: increase potential for contrast‑induced kidney injury.
  • Aminoglycoside antibiotics: additive nephrotoxic effect.
  • Iodine‑containing pharmaceuticals (e.g., thyroid hormones): may amplify iodine load.

Moderate Interactions (Monitor Closely)

  • Beta‑blockers: may mask tachycardia signs of an allergic reaction.
  • Calcium channel blockers: monitor for hypotensive episodes.
  • Anticoagulants: assess bleeding risk if renal function declines.

Frequently Asked Questions

Iomeron is an iodinated contrast agent used to enhance visualization during radiographic procedures such as angiography, computed tomography (CT) scans, and other vascular imaging studies. By increasing X‑ray attenuation, it helps clinicians differentiate blood vessels and tissues, facilitating accurate diagnosis.

Iomeprol is a non‑ionic, low‑osmolar iodine‑containing compound. When injected intravenously or intra‑arterially, the iodine atoms absorb X‑ray photons, raising the attenuation of the blood pool and surrounding structures. This creates a temporary contrast between vascular spaces and adjacent tissues, allowing detailed imaging of anatomical features.

The specific dose of Iomeron is determined by the prescribing physician based on the type of imaging study, patient weight, renal function, and clinical protocol. Dosing is individualized and administered by qualified healthcare professionals under controlled conditions.

Iomeron can cross the placenta and is excreted in breast milk. Use during pregnancy or lactation is only considered when the diagnostic benefit outweighs potential risks. The decision should be made by the treating physician in consultation with the patient, taking into account the lack of definitive safety data.

To place an order, submit an enquiry on the Iomeron product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including any cold‑chain requirements) and necessary import documentation.

Iomeron (iomeprol) is a low‑osmolar, non‑ionic iodinated contrast medium, offering a favorable safety profile compared with high‑osmolar agents that are associated with higher rates of adverse reactions. Compared with other low‑osmolar agents, its iodine concentration provides comparable image quality, while its formulation is designed for both intra‑arterial and intravenous use.

Iomeron should be stored at 2‑8 °C in a refrigerator, protected from light, and must not be frozen or shaken. Keep the vials in their original packaging until use, and allow the solution to reach room temperature before administration if required by the clinical protocol.

Iomeron is supplied as a sterile solution for injection and is administered by a qualified healthcare professional either intravenously or intra‑arterially, depending on the imaging procedure. The injection is typically performed using a power injector or manual bolus, following the dosing instructions set by the radiologist or physician.

The most serious risks include severe allergic reactions such as anaphylaxis, contrast‑induced nephropathy leading to acute kidney injury, and rare cases of cardiovascular collapse or arrhythmias. Patients with known iodine allergy, impaired renal function, or uncontrolled thyroid disease should be closely monitored, and emergency measures must be readily available.

Iomeron is contraindicated in patients with a documented hypersensitivity to iodinated contrast media, those with uncontrolled hyperthyroidism, and individuals with severe renal impairment where alternative imaging methods are feasible. Caution is also advised for patients on metformin or other nephrotoxic drugs, and the decision to use Iomeron should be made by the treating physician after evaluating risks and benefits.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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