Product image of Iomeron (Iomeprol) supplied by GNH India

Iomeron

Active Ingredient:
Iomeprol
Origin:
EU

Iomeron (Iomeprol)

Iomeprol, the active ingredient in Iomeron, is an iodinated non‑ionic contrast media presented as a solution for injection for intra‑arterial and intravenous use. It provides a high iodine concentration that attenuates X‑rays, improving image contrast and diagnostic accuracy in procedures such as angiography, computed tomography and urography.

GNH India supplies Iomeron as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Bracco Uk Ltd

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Indications & Clinical Uses

  • Iomeron is an iodinated non‑ionic contrast agent used to improve visualization of vascular and urinary structures during imaging procedures.
  • Angiography: enhances vessel delineation for diagnostic and interventional procedures.
  • Computed tomography (CT) imaging: provides high‑contrast enhancement for better tissue differentiation.
  • Urography: improves opacification of the urinary tract for detailed assessment.

How It Works

  • Iomeprol contains a high density of iodine atoms that absorb X‑ray photons, increasing attenuation in the vascular and extracellular compartments. After intra‑arterial or intravenous administration, the iodine remains largely within the blood pool, creating a temporary contrast difference between vessels, organs, and surrounding tissues, which allows radiologists to visualize anatomical details with greater clarity during imaging studies.

Side Effects

Adverse reactions may occur after administration of Iomeron. Most are mild and transient, but rare serious events require immediate attention.

Common Side Effects

  • Warm or flushing sensation during injection.
  • Metallic taste or mild nausea.
  • Headache or transient dizziness.
  • Mild hypotension or mild vomiting.

Serious or Rare Side Effects

  • Anaphylactoid or severe allergic reaction.
  • Acute renal impairment, especially in patients with pre‑existing kidney disease.
  • Severe hypotension or cardiovascular collapse.
  • Seizures or neurological disturbances.
  • Pulmonary edema or respiratory distress.

Precautions & Warnings

  • Prior to using Iomeron, clinicians should evaluate patient risk factors and follow safe handling practices.
  • Renal function assessment: evaluate serum creatinine and eGFR before administration.
  • Allergy history: screen for prior reactions to iodinated contrast agents.
  • Thyroid disease: consider risk of iodine‑induced thyroid dysfunction.
  • Pregnancy category B: use only when benefits outweigh potential risks.
  • Pediatric considerations: adjust dose based on body weight and monitor closely.
  • Store at ambient temperature: keep in original container, protect from light and moisture, and avoid freezing.

Avoid Interactions

Iomeron may interact with other medicines, altering safety or efficacy.

Major Interactions (Avoid)

  • Metformin: risk of lactic acidosis in renal impairment; discontinue before contrast.
  • Nephrotoxic agents (e.g., aminoglycosides, amphotericin B): may exacerbate kidney injury.
  • Radioactive iodine therapy: iodine load can interfere with therapeutic efficacy.

Moderate Interactions (Monitor Closely)

  • Diuretics: may affect fluid balance and renal clearance.
  • ACE inhibitors or ARBs: monitor blood pressure and renal function.
  • NSAIDs: increase risk of contrast‑induced nephropathy.
  • Anticoagulants: watch for bleeding if invasive procedures follow contrast use.

Frequently Asked Questions

Iomeron is an iodinated non‑ionic contrast agent used to enhance the visibility of blood vessels, organs, and the urinary tract during radiographic procedures such as angiography, computed tomography (CT) scans, and urography. It improves diagnostic accuracy by providing high‑contrast images.

Iomeprol contains a high concentration of iodine atoms that absorb X‑ray photons. When injected intra‑arterially or intravenously, the iodine remains in the vascular compartment, creating a temporary difference in X‑ray attenuation between blood‑filled structures and surrounding tissues, which results in clearer, more detailed images.

The dose of Iomeron is determined by the prescribing physician based on the specific imaging study, patient weight, renal function, and clinical protocol. Healthcare professionals calculate the appropriate volume and concentration to achieve optimal contrast enhancement while minimizing risk.

Iomeron is classified as pregnancy category B, indicating that animal studies have not shown risk but there are no adequate human studies. It should be used only if the diagnostic benefit justifies potential exposure. Limited data are available for breastfeeding; clinicians should weigh benefits against possible infant exposure.

To order Iomeron, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including cold‑chain if required), and necessary import documentation.

Iomeron is a non‑ionic, low‑osmolality iodinated contrast medium, offering a favorable safety profile compared with older high‑osmolality agents. It provides comparable image quality to other modern non‑ionic agents while reducing the incidence of discomfort and adverse reactions, making it a preferred choice for many radiology departments.

Iomeron should be stored at ambient temperature, below 25 °C, in its original sealed container. Protect the solution from direct sunlight, moisture, and freezing. Do not shake the vial vigorously; gently invert if mixing is required before administration.

Iomeron is supplied as a sterile solution for injection and is administered intravenously or intra‑arterially by a qualified healthcare professional. The injection rate and total volume are tailored to the imaging protocol and patient characteristics to achieve optimal contrast enhancement.

The most serious risks include severe allergic or anaphylactoid reactions, acute renal impairment, and cardiovascular collapse such as severe hypotension. Patients with known iodine allergy, compromised kidney function, or uncontrolled thyroid disease require careful assessment before use.

Iomeron should be avoided in patients with a documented severe hypersensitivity to iodinated contrast media, uncontrolled hyperthyroidism, or those who are unable to undergo emergency treatment for anaphylaxis. Caution is also advised for patients with severe renal insufficiency or those on contraindicated medications.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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