Product image of Ionovol (Magnesium Chloride Hexahydrate, Potassium Chloride, Sodium Chloride, Sodium Acetate Trihydrate) supplied by GNH India

Ionovol

Active Ingredient:
Magnesium Chloride Hexahydrate, Potassium Chloride, Sodium Chloride, Sodium Acetate Trihydrate
Origin:
EU

Ionovol (Magnesium Chloride Hexahydrate, Potassium Chloride, Sodium Chloride, Sodium Acetate Trihydrate)

Magnesium Chloride Hexahydrate, Potassium Chloride, Sodium Chloride and Sodium Acetate Trihydrate, the active ingredient in Ionovol, is an IV electrolyte solution presented as a solution for injection for intravenous use. It restores electrolyte balance and plasma volume in patients requiring fluid and electrolyte therapy.

GNH India supplies Ionovol as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals worldwide.

Manufacturer / TM Owner

Fresenius Kabi Italia S.R.L.

1
Pack/s
This product is added to your enquiry list

Request a Quote

Please fill out the form below and our team will get back to you shortly with pricing and further information.

A minimum order value applies. Our team will confirm the exact amount or quantity after reviewing your requirements.

Indications & Clinical Uses

  • Ionovol acts on the body’s fluid and electrolyte balance to correct deficiencies and support circulatory volume.
  • Electrolyte replacement: restores deficient magnesium, potassium, sodium and acetate ions in patients with losses due to surgery, diarrhea or chronic disease.
  • Fluid resuscitation: expands intravascular volume in hypovolemic patients to improve perfusion.
  • Treatment of hypomagnesemia: supplies magnesium to correct low serum magnesium levels.
  • Treatment of hypokalemia: provides potassium to normalize serum potassium.
  • Treatment of hyponatremia: delivers sodium to raise low serum sodium concentrations.

How It Works

  • Ionovol dissociates after intravenous administration, releasing magnesium, potassium, sodium and acetate ions into the bloodstream. Magnesium supports enzymatic activity, potassium maintains cellular membrane potential, sodium contributes to extracellular fluid volume, and acetate is metabolized to bicarbonate, helping correct acid‑base disturbances while restoring overall electrolyte homeostasis.

Side Effects

Ionovol may be associated with a range of adverse reactions.

Common Side Effects

  • Infusion site irritation or pain.
  • Mild hypermagnesemia presenting as flushing or nausea.
  • Mild hyperkalemia causing transient muscle weakness.
  • Nausea or vomiting.
  • Headache.
  • Dizziness.

Serious or Rare Side Effects

  • Severe hypermagnesemia leading to respiratory depression or cardiac arrest.
  • Severe hyperkalemia causing life‑threatening arrhythmias.
  • Anaphylactic or severe allergic reaction.
  • Cardiac arrhythmia unrelated to electrolyte excess.
  • Metabolic acidosis from acetate accumulation.
  • Hypotension due to rapid infusion.

Precautions & Warnings

  • Before initiating therapy, clinicians should evaluate the patient’s baseline electrolyte status and renal function.
  • Assess electrolyte levels: verify serum magnesium, potassium, sodium and acetate before and during treatment.
  • Monitor cardiac function: observe ECG for arrhythmias, especially in patients with cardiac disease.
  • Adjust dose in renal impairment: reduce infusion rate or volume in patients with reduced renal clearance.
  • Use caution in heart block: avoid rapid infusion that may exacerbate conduction abnormalities.
  • Avoid rapid infusion: administer over the recommended period to prevent circulatory overload.
  • Store at ambient temperature: keep below 25 °C, in the original packaging, protected from moisture and direct light.

Avoid Interactions

Ionovol can interact with several medications and solutions.

Major Interactions (Avoid)

  • Concurrent IV electrolyte solutions: risk of electrolyte overload.
  • Calcium‑containing solutions: potential precipitation of calcium‑magnesium salts.
  • Loop diuretics: increase loss of administered electrolytes.
  • ACE inhibitors or ARBs: heightened risk of hyperkalemia.
  • Sodium bicarbonate: may alter acetate metabolism.

Moderate Interactions (Monitor Closely)

  • NSAIDs: may impair renal function affecting electrolyte clearance.
  • Digoxin: electrolyte shifts can modify digoxin toxicity.
  • Anticoagulants: fluid shifts may affect bleeding risk.
  • Beta‑blockers: combined hypotensive effects.
  • Corticosteroids: may cause fluid retention and alter electrolyte balance.

Frequently Asked Questions

Ionovol is an intravenous electrolyte solution indicated for replacement of deficient electrolytes and fluid resuscitation in patients with conditions such as hypomagnesemia, hypokalemia, hyponatremia, or volume depletion. It provides magnesium, potassium, sodium, and acetate ions to restore plasma volume and electrolyte balance.

The magnesium chloride, potassium chloride, sodium chloride and sodium acetate in Ionovol dissociate in the bloodstream, delivering essential cations and anions. Magnesium supports enzymatic reactions, potassium maintains cellular membrane potential, sodium contributes to extracellular fluid volume, and acetate is metabolized to bicarbonate, helping correct acid‑base disturbances.

The dosage of Ionovol is individualized by the prescribing clinician based on the patient’s electrolyte deficits, fluid status, and clinical condition. The prescriber determines the infusion rate, total volume, and duration according to laboratory values and therapeutic goals. No standard dose is provided here.

The safety of Ionovol during pregnancy and lactation has not been fully established, and the product lacks a specific pregnancy category. Use in pregnant or nursing women should be considered only if the potential benefit justifies the potential risk, and it must be prescribed and monitored by a qualified healthcare professional.

To order Ionovol, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including cold‑chain if required), and necessary import documentation.

The primary alternative to Ionovol is other IV electrolyte solutions such as Ringer’s lactate or normal saline combined with separate electrolyte supplements. Ionovol offers a balanced combination of magnesium, potassium, sodium, and acetate in a single formulation, which can simplify dosing and reduce the need for multiple infusions compared with using separate solutions.

Ionovol should be stored at controlled room temperature, below 25 °C, in its original packaging to protect it from moisture and direct sunlight. The container must be kept sealed until use, and any solution that appears discolored or contains particles should be discarded. No refrigeration is required.

Ionovol is administered intravenously as a sterile solution for injection. The infusion is typically delivered through a calibrated IV set, with the rate adjusted according to the patient’s electrolyte levels and clinical response. Administration should be performed by trained healthcare personnel in a setting equipped for monitoring vital signs and potential infusion reactions.

The most serious risks associated with Ionovol include severe hypermagnesemia or hyperkalemia, which can cause cardiac arrhythmias, respiratory depression, or hypotension, as well as anaphylactic or severe allergic reactions. Prompt monitoring of electrolyte concentrations, cardiac function, and infusion site is essential to detect and manage these complications early.

Ionovol should be avoided in patients with known hypersensitivity to any of its components, those with severe renal impairment where electrolyte excretion is compromised, and individuals with existing life‑threatening hypermagnesemia, hyperkalemia, or hypernatremia. It is also contraindicated when concurrent administration of incompatible IV solutions could cause precipitation.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

Disclaimer

At GNH India, we aim to provide information that is expert-reviewed, accurate, and reliable. However, all content on this platform is intended for general informational purposes only and does not constitute professional medical advice, diagnosis, or treatment. While efforts are made to maintain accuracy and currency, the information may contain errors, omissions, or may not reflect the latest developments. Always consult a qualified healthcare professional regarding any medical concerns.

All product names, brand names, trademarks and registered trademarks displayed on this website are the property of their respective owners. This website and its operator are not affiliated with, endorsed by, or authorized by any such trade mark owners unless expressly stated. Any reference to product names or trademarks is made solely for descriptive and informational purposes. No commercial relationship, sponsorship, approval, or association with any trademark owner should be inferred. Information provided herein does not constitute promotion, advertising, or an offer for sale of any medicinal product and is intended solely for general informational purposes.

All trademarks and brand names displayed on this website are used strictly in accordance with the provisions of the Trade Marks Act, 1999, specifically Sections 30 and 30(1) governing fair use. Trademark ownership has been accurately attributed under the "Manufacturer/ TM Owner" section in compliance with statutory requirements.

Ordering Process

Simple, Secure, and Seamless

Learn how our streamlined ordering process guarantees fast, compliant, and reliable access to essential medicines worldwide.

Quote request form

01

Submit Quote Request Form

Tell us what medications you need by filling out our simple form and uploading a valid document.

Price estimate review

02

We Review & Send Estimate

Our licensed pharmacists will verify your details and provide you with a detailed cost estimate.

Secure payment

03

Confirm & Make Payment

Discuss any queries, approve the estimate, and complete your payment.

Worldwide delivery

04

Get Delivered

Your medicines, safely packed and delivered to your door or nearest airport — hassle-free.

Quality You Can Trust

Our internationally recognized certifications underscore our commitment to safety, quality, and excellence.