Product image of Iopamiro 150 (Iopamidol) supplied by GNH India

Iopamiro 150

Active Ingredient:
Iopamidol
Origin:
EU

Iopamiro 150 (Iopamidol)

Iopamidol, the active ingredient in Iopamiro 150, is an iodinated contrast media presented as a 150 mg I/mL injectable solution for intravenous use. It enhances radiographic imaging of blood vessels and tissues during diagnostic procedures, helping clinicians obtain clearer images for accurate diagnosis.

GNH India supplies Iopamiro 150 as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals worldwide.

Manufacturer / TM Owner

Bracco Imaging S.P.A.

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Indications & Clinical Uses

Iopamiro 150, an iodinated contrast agent, is used to improve visualization of vascular and organ structures in radiographic examinations.

  • Computed tomography (CT) scans: provides enhanced contrast to delineate vascular and soft‑tissue structures.
  • Angiography: highlights blood vessels to aid in the assessment of arterial and venous anatomy.
  • Urography: improves the definition of urinary tract anatomy for functional and structural evaluation.
  • Myelography: enhances the spinal canal and nerve root imaging during contrast studies.
  • Cardiac catheterisation: increases contrast between cardiac chambers and vessels for precise procedural guidance.

How It Works

  • Iopamidol contains multiple iodine atoms that strongly absorb X‑ray photons. When injected intravenously, the iodine increases the radiodensity of blood and extracellular fluid, creating a temporary contrast between vascular or tissue compartments and surrounding structures. This differential attenuation allows imaging systems to generate high‑resolution images that reveal anatomical details not visible on non‑contrast studies.

Side Effects

Iopamiro 150 may cause a range of adverse reactions, from mild to severe. Awareness of these effects helps clinicians monitor patients during and after administration.

Common Side Effects

  • Warmth or flushing sensation at the injection site.
  • Metallic taste in the mouth.
  • Nausea or mild vomiting.
  • Transient headache or dizziness.

Serious or Rare Side Effects

  • Anaphylactic or severe allergic reactions, including bronchospasm.
  • Acute kidney injury, especially in patients with pre‑existing renal impairment.
  • Severe hypotension or cardiovascular collapse.
  • Pulmonary edema or acute respiratory distress.
  • Cardiac arrhythmias in susceptible individuals.

Precautions & Warnings

Prior to using Iopamiro 150, clinicians should consider several safety measures to minimise risk.

  • Assess renal function: evaluate serum creatinine and eGFR before administration.
  • Review iodine allergy history: avoid in patients with known hypersensitivity to iodinated contrast.
  • Use the lowest effective dose: tailor volume to the specific imaging protocol.
  • Monitor vital signs: observe blood pressure and heart rate during injection.
  • Caution in thyroid disease: avoid in uncontrolled hyperthyroidism or thyroid storm.
  • Store at 2-8°C: keep refrigerated, protect from light, do not freeze or shake.

Avoid Interactions

Iopamiro 150 can interact with other medications, requiring careful management.

Major Interactions (Avoid)

  • Concurrent use of other iodinated contrast agents: increases cumulative iodine load.
  • High‑dose metformin in patients with renal impairment: risk of lactic acidosis.
  • Nephrotoxic drugs (e.g., aminoglycosides, NSAIDs): may exacerbate renal injury.

Moderate Interactions (Monitor Closely)

  • Thyroid hormone therapy: contrast may affect thyroid function tests.
  • Diuretics: may alter fluid balance and affect contrast distribution.
  • Beta‑blockers: monitor for potential changes in heart rate during injection.

Frequently Asked Questions

Iopamiro 150 is an iodinated contrast medium used to enhance the visibility of blood vessels, organs, and tissues during diagnostic imaging procedures such as computed tomography (CT), angiography, urography, myelography, and cardiac catheterisation. By increasing radiodensity, it helps radiologists obtain clearer images for accurate diagnosis.

Iopamidol contains iodine atoms that strongly absorb X‑ray photons. When injected intravenously, the iodine raises the radiodensity of the blood and extracellular fluid, creating a contrast difference between vascular or tissue compartments and surrounding structures. This differential attenuation allows imaging equipment to produce high‑resolution pictures of anatomical details.

The dose of Iopamiro 150 is determined by the prescribing physician based on the specific imaging study, patient size, renal function, and clinical need. The healthcare provider calculates the appropriate volume and concentration to achieve optimal contrast while minimizing risk.

Safety data for Iopamiro 150 in pregnancy are limited, and the product is classified as having an unknown pregnancy category. It should only be used when clearly needed and when the potential diagnostic benefit outweighs any possible risk to the fetus. Breastfeeding mothers should consult their physician, as the drug may be excreted in milk.

To order Iopamiro 150, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India supplies hospitals, pharmacies, and procurement teams worldwide. After submission, the sales team will verify trade or institutional credentials, then provide pricing, availability, shipping details (including any cold‑chain requirements), and assist with import documentation.

Iopamiro (iopamidol) is a non‑ionic, low‑osmolality iodinated contrast medium, offering a favorable safety profile compared with older high‑osmolality agents. It provides comparable image quality to other low‑osmolality agents such as iohexol or iopromide, but with reduced incidence of discomfort and adverse reactions, making it a preferred choice for many diagnostic procedures.

Iopamiro 150 should be stored at 2‑8 °C (refrigerated). Keep the vials in their original packaging, protect them from light, and avoid freezing or shaking the solution. If the product reaches room temperature, it may be used within the time frame specified in the manufacturer’s labeling.

Iopamiro 150 is administered intravenously, typically via a power injector or manual bolus injection, depending on the imaging protocol. The injection rate and volume are selected by the radiologist or technologist to achieve optimal contrast enhancement for the specific diagnostic study.

The most serious risks include severe allergic reactions such as anaphylaxis, acute kidney injury especially in patients with pre‑existing renal impairment, and significant hypotension or cardiovascular collapse. Prompt recognition and management of these reactions are essential during and after administration.

Iopamiro 150 should be avoided in patients with a known hypersensitivity to iodinated contrast media, severe renal dysfunction (e.g., eGFR < 30 mL/min/1.73 m²), uncontrolled hyperthyroidism, or a history of severe allergic reactions to contrast agents. Clinicians must evaluate each patient’s risk factors before use.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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