Product image of Iopamiro 200 (Iopamidol) supplied by GNH India

Iopamiro 200

Active Ingredient:
Iopamidol
Origin:
EU

Iopamiro 200 (Iopamidol)

Iopamidol, the active ingredient in Iopamiro 200, is a iodinated contrast agent presented as a 200 mg I/mL injection solution for intravenous use. It provides radiopaque contrast for diagnostic imaging procedures and is employed in patients undergoing computed tomography, angiography, urography, myelography and other studies that require enhanced visualization of vascular and tissue structures.

GNH India supplies Iopamiro 200 as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Bracco Imaging S.P.A.

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Indications & Clinical Uses

  • Iopamiro 200, an iodinated contrast agent, is used in radiographic procedures that require enhanced X‑ray attenuation.
  • Contrast‑enhanced computed tomography (CT): improves delineation of organs and lesions during CT scans.
  • Angiography: provides clear visualization of blood vessels for diagnostic and interventional procedures.
  • Urography: enhances imaging of the urinary tract to detect obstructions or stones.
  • Myelography: facilitates detailed imaging of the spinal canal and nerve roots.

How It Works

  • Iopamidol is a non‑ionic, low‑osmolality iodinated compound that absorbs X‑rays due to the high atomic number of iodine. After intravenous injection, it distributes in the extracellular fluid, temporarily increasing the radiodensity of blood and tissues, which allows X‑ray based imaging systems to differentiate anatomical structures without interacting with cellular receptors.

Side Effects

Iopamiro 200 may be associated with adverse reactions following intravenous administration.

Common Side Effects

  • Warm sensation or flushing: transient feeling of heat at the injection site.
  • Nausea: mild to moderate upset stomach.
  • Headache: mild headache during or after the procedure.
  • Metallic taste: temporary alteration of taste perception.

Serious or Rare Side Effects

  • Allergic reaction: urticaria, bronchospasm, or anaphylaxis requiring immediate treatment.
  • Contrast‑induced nephropathy: acute kidney injury, especially in patients with pre‑existing renal impairment.
  • Cardiovascular collapse: hypotension or arrhythmia in rare cases.

Precautions & Warnings

Prior to using Iopamiro 200, clinicians should consider several safety precautions.

  • Renal function assessment: evaluate serum creatinine and eGFR before administration.
  • Allergy history: screen for prior reactions to iodinated contrast or iodine‑containing products.
  • Hydration status: ensure adequate patient hydration to reduce risk of nephropathy.
  • Thyroid disease: monitor patients with hyper‑ or hypothyroidism due to iodine load.
  • Pregnancy and lactation: use only if benefits outweigh potential risks, as safety data are limited.
  • Store at ambient temperature: keep below 25 °C, protect from light and moisture, and retain in original packaging.

Avoid Interactions

Iopamiro 200 can interact with certain medications or conditions that affect contrast safety.

Major Interactions (Avoid)

  • Concurrent nephrotoxic drugs (e.g., aminoglycosides, NSAIDs): increase risk of renal injury – avoid co‑administration if possible.
  • High‑dose iodine supplements or thyroid hormone therapy: may exacerbate thyroid dysfunction – avoid.

Moderate Interactions (Monitor Closely)

  • Metformin: risk of lactic acidosis in renal impairment – hold metformin before and after contrast as per guidelines.
  • Beta‑blockers: may mask contrast‑induced hypertension – monitor blood pressure closely.
  • Diuretics: can affect fluid balance and renal clearance – assess hydration status.

Frequently Asked Questions

Iopamiro 200 is an iodinated contrast medium used to enhance X‑ray based imaging studies such as contrast‑enhanced computed tomography, angiography, urography, and myelography. By increasing the radiodensity of blood and tissues, it allows clinicians to obtain clearer images of vascular structures and organ anatomy during diagnostic procedures.

Iopamidol contains iodine atoms that strongly absorb X‑rays. When injected intravenously, it distributes in the extracellular fluid and temporarily raises the radiodensity of blood vessels and tissues. This physical attenuation of X‑rays creates a contrast between structures, enabling detailed visualization on CT scans, angiograms, and other imaging modalities.

The dose of Iopamiro 200 is determined by the prescribing physician based on the specific imaging protocol, patient size, and clinical indication. Dosing is individualized and should follow the recommendations of the imaging department and relevant guidelines; no fixed regimen is provided here.

Safety data for Iopamiro 200 in pregnancy and lactation are limited. It should be used only when the potential diagnostic benefit justifies any possible risk to the fetus or infant. Clinicians should discuss the risk‑benefit profile with the patient and consider alternative imaging methods when appropriate.

To order Iopamiro 200, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India supplies hospitals, pharmacies and procurement teams across international markets. After submission, the sales team will verify trade or institutional credentials and respond with pricing, availability, shipping details (including any cold‑chain requirements), and import documentation.

Iopamiro 200 contains iopamidol, a non‑ionic, low‑osmolality iodinated contrast agent. Compared with older ionic, high‑osmolality agents, it generally produces fewer immediate adverse reactions and is better tolerated, especially in patients with compromised renal function. Its imaging performance is comparable, providing high‑quality contrast enhancement for a wide range of diagnostic studies.

Iopamiro 200 should be stored at ambient temperature, preferably below 25 °C. Keep the vials in their original packaging, protect them from light and moisture, and avoid freezing. Inspect the solution for particulate matter or discoloration before use, and discard any product that appears compromised.

Iopamiro 200 is administered by intravenous injection, typically using a power injector to deliver a controlled volume at a specific rate as defined by the imaging protocol. The solution may be diluted with compatible sterile fluids according to the procedure requirements, and administration should be performed by trained healthcare professionals.

The most serious risks associated with Iopamiro 200 include severe allergic reactions such as anaphylaxis, contrast‑induced nephropathy leading to acute kidney injury, and rare cardiovascular events like hypotension or arrhythmia. Prompt recognition and management of these reactions are essential, and patients with known risk factors should be closely monitored.

Iopamiro 200 should be avoided in patients with a documented hypersensitivity to iodinated contrast media, severe renal impairment (e.g., eGFR < 30 mL/min/1.73 m²), uncontrolled thyroid disease, or in those who have experienced prior severe reactions to similar agents. Clinicians must assess individual risk factors before administration.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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