Product image of Iopamiro 300 (Iopamidol) supplied by GNH India

Iopamiro 300

Active Ingredient:
Iopamidol
Origin:
EU

Iopamiro 300 (Iopamidol)

Iopamidol, the active ingredient in Iopamiro 300, is an iodinated contrast media presented as a 300 mg I/mL injectable solution for intraarterial, intraarticular, or intrathecal use. It provides radiodensity that enhances X‑ray visualization of vascular, joint and spinal structures during diagnostic imaging procedures.
GNH India supplies Iopamiro 300 as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals worldwide.

Manufacturer / TM Owner

Bracco Imaging S.P.A.

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Indications & Clinical Uses

  • Iopamiro 300, an iodinated contrast agent, is employed in diagnostic imaging procedures that require vascular, joint or spinal contrast enhancement.
  • Angiography: improves visualization of blood vessels and vascular lesions.
  • Arthrography: enhances delineation of joint spaces and cartilage.
  • Myelography: provides contrast for spinal canal and nerve root imaging.
  • Other diagnostic imaging procedures: supplies intra‑vascular, intra‑articular or intrathecal contrast for a range of radiographic studies.

How It Works

  • Iopamidol delivers a high concentration of iodine atoms that increase X‑ray attenuation when injected into the body. The iodine atoms absorb X‑ray photons, creating radiodense areas that appear brighter on radiographic images, thereby improving the contrast between vascular, joint or spinal structures and surrounding tissues during imaging examinations.

Side Effects

Iopamiro 300 may cause a range of adverse reactions following injection.

Common Side Effects

  • Warmth or flushing sensation at the injection site
  • Nausea or vomiting
  • Metallic taste in the mouth
  • Mild headache
  • Transient hypotension or dizziness
  • Injection site pain or bruising

Serious or Rare Side Effects

  • Severe allergic reaction or anaphylaxis
  • Contrast‑induced nephropathy or acute renal failure
  • Seizures or convulsions
  • Cardiac arrhythmias or severe hypotension
  • Pulmonary edema or respiratory distress
  • Persistent skin rash or urticaria

Precautions & Warnings

  • Prior to administration, clinicians should evaluate patient-specific risk factors and follow safe handling practices.
  • Assess renal function: check serum creatinine and eGFR before use.
  • Review allergy history: avoid in patients with known iodine or contrast media hypersensitivity.
  • Use lowest effective iodine dose: tailor volume to imaging requirement.
  • Monitor vital signs: observe for hemodynamic changes during and after injection.
  • Avoid in severe renal impairment: consider alternative imaging modalities.
  • Store at 2-8°C: keep refrigerated, protect from light, do not freeze or shake.

Avoid Interactions

Iopamiro 300 can interact with other agents that affect renal function or iodine load.

Major Interactions (Avoid)

  • Concurrent administration of other iodinated contrast media: cumulative iodine may increase toxicity.
  • Use with nephrotoxic drugs (e.g., aminoglycosides, NSAIDs): heightened risk of renal injury.
  • Co‑administration with metformin in patients with reduced renal function: risk of lactic acidosis.

Moderate Interactions (Monitor Closely)

  • Concomitant diuretics: may alter fluid balance and affect contrast distribution.
  • Beta‑blockers or antihypertensives: monitor blood pressure for additive hypotensive effects.
  • Systemic steroids: may mask early signs of allergic reactions.

Frequently Asked Questions

Iopamiro 300 is an iodinated contrast medium used to enhance X‑ray based imaging studies such as angiography, arthrography and myelography. By increasing radiodensity of blood vessels, joints or the spinal canal, it helps radiologists obtain clearer images for accurate diagnosis.

Iopamidol contains iodine atoms that strongly absorb X‑ray photons. When injected, these atoms create radiodense zones that appear brighter on radiographs, allowing clinicians to differentiate vascular, joint or spinal structures from surrounding tissues during imaging procedures.

The dose of Iopamiro 300 is determined by the prescribing physician based on the specific imaging protocol, patient size, and the anatomical area to be examined. The prescriber selects the appropriate volume and concentration to achieve optimal contrast while minimizing exposure.

Safety of Iopamiro 300 in pregnancy and lactation has not been established. It should only be used when clearly needed and when the potential diagnostic benefit outweighs any possible risk to the fetus or infant. Consultation with obstetric specialists is recommended.

To order Iopamiro 300, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including cold‑chain if required) and necessary import documentation.

Iopamiro 300 (iopamidol) offers a low‑osmolality profile similar to other modern agents such as iohexol, providing good image quality with a reduced incidence of discomfort and adverse reactions compared with high‑osmolality agents. Choice between agents often depends on specific imaging needs, institutional protocols and patient tolerance.

Iopamiro 300 should be stored at 2‑8 °C in a refrigerator, protected from light. Do not freeze or shake the vial. Keep the product in its original packaging until use to maintain sterility and potency.

Iopamiro 300 is administered by a qualified healthcare professional via intra‑arterial, intra‑articular or intrathecal injection, depending on the imaging study. The solution is injected directly into the target vascular, joint or spinal space under controlled conditions, often using a power injector for consistent delivery.

The most serious risks include severe allergic reactions such as anaphylaxis, contrast‑induced nephropathy leading to acute renal failure, and cardiovascular events like severe hypotension or arrhythmias. Immediate medical attention is required if any of these reactions occur.

Iopamiro 300 should be avoided in patients with a known hypersensitivity to iodine or iodinated contrast media, those with severe renal impairment (eGFR <30 mL/min/1.73 m²), and individuals who have experienced prior severe reactions to contrast agents. Clinicians must assess risk before administration.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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