Product image of Iopamiro (Iopamidol) supplied by GNH India

Iopamiro

Active Ingredient:
Iopamidol
Origin:
EU

Iopamiro (Iopamidol)

Iopamidol, the active ingredient in Iopamiro, is a iodinated contrast media presented as a solution for injection for intraarterial, intraarticular and intrathecal use. It enhances X‑ray attenuation, improving visualization of vascular and tissue structures during imaging procedures.

GNH India supplies Iopamiro as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, diagnostic centres and imaging clinics worldwide, ensuring EU‑standard quality and reliable global distribution.

Manufacturer / TM Owner

Bracco Imaging S.P.A.

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Indications & Clinical Uses

Iopamiro is an iodinated contrast medium used in diagnostic imaging procedures that require enhanced visualization of vascular, joint and spinal structures.

  • Angiography: provides high‑contrast images of blood vessels to aid in vascular assessment.
  • Arthrography: improves delineation of joint spaces and cartilage for orthopedic evaluation.
  • Myelography: enhances visualization of the spinal canal and nerve roots during contrast‑enhanced spinal imaging.

How It Works

  • Iopamidol contains iodine atoms with a high atomic number that strongly absorb X‑ray photons. After injection, the compound distributes rapidly within the intravascular and extracellular compartments, increasing the attenuation of X‑ray beams passing through the area of interest. This heightened attenuation creates a marked difference in radiodensity between the contrast‑filled structures and surrounding tissues, thereby producing clearer, high‑contrast images for diagnostic interpretation.

Side Effects

Iopamiro may cause a range of adverse reactions, from mild to severe.

Common Side Effects

  • Warm sensation or flushing at the injection site
  • Metallic taste in the mouth
  • Nausea or mild headache

Serious or Rare Side Effects

  • Severe allergic reactions, including anaphylaxis
  • Acute kidney injury in susceptible patients
  • Cardiovascular collapse or hypotension

Precautions & Warnings

When using Iopamiro, clinicians should observe several safety measures.

  • Renal function: assess baseline kidney function and adjust dose in impaired patients.
  • Allergy history: screen for previous reactions to iodinated contrast agents.
  • Thyroid status: monitor patients with hyperthyroidism as iodine load may exacerbate condition.
  • Pregnancy: use only when essential after risk‑benefit evaluation.
  • Concomitant nephrotoxic drugs: avoid or monitor when combined with NSAIDs, aminoglycosides, or radiographic contrast.
  • Store at controlled room temperature: keep below 25 °C in original container, protect from light and moisture.

Avoid Interactions

Iopamiro can interact with other medications, requiring careful management.

Major Interactions (Avoid)

  • Metformin: risk of lactic acidosis in renal impairment; discontinue before procedure.
  • NSAIDs: may increase risk of contrast‑induced nephropathy.
  • Diuretics: can exacerbate renal dysfunction when combined with contrast.

Moderate Interactions (Monitor Closely)

  • ACE inhibitors or ARBs: may affect renal perfusion; monitor kidney function.
  • Iodine‑containing medications: potential additive iodine load.
  • Radiopharmaceuticals: consider timing to avoid interference.

Frequently Asked Questions

Iopamiro is a sterile solution containing iopamidol, an iodinated contrast medium used in diagnostic imaging procedures such as angiography, arthrography, and myelography to improve visualization of vascular and tissue structures.

Iopamidol contains iodine atoms that have a high atomic number, which absorb X‑rays. When injected, it distributes in the vascular and extracellular compartments, increasing X‑ray attenuation and creating a clear contrast between the enhanced structures and surrounding tissues.

The dose of Iopamiro is determined by the prescribing physician based on the specific imaging study, patient weight, renal function, and the required level of contrast enhancement. The healthcare professional selects the appropriate volume and concentration for each procedure.

Safety of iopamidol in pregnancy and lactation has not been fully established. It should only be used when clearly needed and after a careful risk‑benefit assessment by the clinician. Breastfeeding mothers should discuss any precautions with their physician.

To place an order, submit an enquiry on the product page at gnhindia.com, providing the required quantity and institutional details. GNH India supplies hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then replies with pricing, availability, shipping terms and any necessary import documentation.

Iopamiro (iopamidol) is a non‑ionic, low‑osmolality contrast medium, offering a favorable safety profile compared with older high‑osmolality agents. It provides comparable image quality to other non‑ionic agents such as iohexol, while reducing the incidence of discomfort and adverse reactions.

Iopamiro should be stored at controlled room temperature, below 25 °C, in its original container. Protect the solution from light and moisture, and avoid freezing. Inspect the vial for particulate matter before use and discard if any is present.

Iopamiro is supplied as a sterile solution for injection and is administered intravenously, intra‑arterially, intra‑articularly, or intrathecally by a qualified healthcare professional, following the protocol of the specific imaging procedure and using aseptic technique.

Serious adverse reactions, although rare, include severe allergic responses such as anaphylaxis, acute kidney injury, hypotension, seizures, and cardiopulmonary arrest. Prompt recognition and appropriate emergency management are essential if these events occur.

Iopamiro is contraindicated in patients with a known hypersensitivity to iopamidol or other iodinated contrast agents, those with severe renal impairment, uncontrolled hyperthyroidism, or a history of severe adverse reactions to contrast media. Clinicians should evaluate each patient before administration.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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