Product image of Iopamiro (Iopamidol) supplied by GNH India

Iopamiro

Active Ingredient:
Iopamidol
Origin:
EU

Iopamiro (Iopamidol)

Iopamidol, the active ingredient in Iopamiro, is an iodinated contrast media presented as a sterile injectable solution for intra‑arterial, intrathecal, and intravenous use. It provides high‑density radiographic contrast that improves visualization of vascular structures, soft tissues, and the spinal canal during angiography, computed tomography (CT) scans, and myelography procedures.

GNH India supplies Iopamiro as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, clinics and imaging centers worldwide, and research institutions, ensuring reliable access to quality contrast media for diagnostic imaging.

Manufacturer / TM Owner

Bracco Imaging S.P.A.

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Indications & Clinical Uses

Iopamiro, an iodinated contrast medium, is used in diagnostic imaging to enhance visualization of vascular and tissue structures.

  • Vascular imaging (angiography): provides enhanced contrast of blood vessels for detailed angiographic assessment.
  • Computed tomography (CT) scans: improves tissue differentiation and organ delineation during CT imaging.
  • Myelography: outlines the spinal canal and nerve roots for clearer myelographic studies.

How It Works

  • Iopamidol contains a high concentration of iodine atoms that strongly absorb X‑ray photons. When injected, the iodine increases the attenuation of the X‑ray beam in the region of interest, creating a marked difference in radiodensity between the contrast‑filled vessels or spaces and surrounding tissues. This contrast enhancement allows radiologists to obtain clearer images of vascular anatomy, organ parenchyma, and the spinal canal during various imaging modalities.

Side Effects

Iopamiro may be associated with a range of adverse reactions, varying from mild to severe.

Common Side Effects

  • Warm sensation or flushing at injection site
  • Metallic taste or mild nausea
  • Headache
  • Transient dizziness

Serious or Rare Side Effects

  • Severe allergic or anaphylactoid reaction
  • Acute renal impairment
  • Seizures or neurologic disturbances
  • Cardiovascular collapse

Precautions & Warnings

Before administering Iopamiro, several precautions should be observed.

  • Assess renal function: evaluate serum creatinine and eGFR before administration.
  • Review allergy history: identify prior reactions to iodinated contrast agents.
  • Use lowest effective dose: tailor volume to patient size and imaging requirement.
  • Monitor for hypersensitivity: observe patient during and after injection for signs of reaction.
  • Avoid in severe iodine allergy: contraindicated in patients with known severe hypersensitivity to iodine.
  • Store at ambient temperature: keep below 25 °C in original packaging, protect from light and moisture.

Avoid Interactions

Iopamiro can interact with certain medications and substances.

Major Interactions (Avoid)

  • Concurrent use of other high‑osmolality iodinated contrast agents: increase risk of toxicity.
  • Metformin in patients with impaired renal function: risk of lactic acidosis.
  • Aminoglycoside antibiotics in renal‑compromised patients: additive nephrotoxicity.

Moderate Interactions (Monitor Closely)

  • Diuretics (e.g., furosemide): may affect renal clearance of contrast.
  • ACE inhibitors or ARBs: monitor renal function and electrolytes.
  • NSAIDs: potential for reduced renal perfusion.
  • Thyroid hormone replacement: iodine load may affect thyroid function tests.

Frequently Asked Questions

Iopamiro is a sterile iodinated contrast medium containing iopamidol, employed in diagnostic imaging procedures such as angiography, computed tomography (CT) scans, and myelography to enhance visualization of vascular structures and tissues.

Iopamidol provides radiographic contrast by delivering a high concentration of iodine atoms that absorb X‑ray photons, increasing attenuation of the beam in the administered area. This creates a difference in radiodensity between contrast‑filled vessels or spaces and surrounding tissues, allowing clearer imaging.

The dose of Iopamiro is individualized by the prescribing physician based on the specific imaging study, patient size, renal function, and the required level of contrast enhancement. The healthcare professional determines the appropriate volume and concentration for each procedure.

The safety of Iopamiro during pregnancy or lactation has not been definitively established. It should be used only if the potential diagnostic benefit outweighs any possible risk to the fetus or infant, and the decision should be made by the treating physician in consultation with the patient.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India supplies hospitals, pharmacies and procurement teams worldwide, and will request verification of trade or institutional credentials before providing pricing, availability, shipping details (including any cold‑chain requirements) and import documentation.

Iopamiro contains iopamidol, a non‑ionic, low‑osmolality iodinated contrast medium, which generally offers a lower incidence of discomfort and adverse reactions compared with older high‑osmolality agents. Its imaging performance is comparable to other low‑osmolality agents, while providing good vascular and tissue enhancement for angiography, CT and myelography.

Iopamiro should be stored at controlled room temperature, below 25 °C, in its original packaging to protect it from light and moisture. Do not freeze the product, and keep it out of reach of children. Verify the expiry date before use.

Iopamiro is administered by a qualified healthcare professional via intra‑arterial, intravenous or intrathecal injection, depending on the imaging procedure. The injection is typically performed using a sterile technique, and the volume and rate are adjusted according to the specific diagnostic requirement and patient factors.

The most serious risks include severe allergic or anaphylactoid reactions, renal toxicity especially in patients with pre‑existing kidney impairment, and rare neurologic events such as seizures. Prompt recognition and management of these reactions are essential, and patients should be monitored closely during and after administration.

Iopamiro should be avoided in patients with a known hypersensitivity to iopamidol or any iodinated contrast media, those with severe renal insufficiency where alternative imaging is possible, and individuals with a history of severe iodine‑related allergic reactions. The prescribing clinician must assess each patient’s risk before use.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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