Product image of Iopamiro (Iopamidol) supplied by GNH India

Iopamiro

Active Ingredient:
Iopamidol
Origin:
EU

Iopamiro (Iopamidol)

Iopamidol, the active ingredient in Iopamiro, is a nonionic iodinated contrast agent presented as a solution for injection for intraarterial and intravenous use. It provides contrast enhancement for imaging procedures and is used in patients undergoing radiographic examinations.

GNH India supplies Iopamiro as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals worldwide.

Manufacturer / TM Owner

Bracco Imaging S.P.A.

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Indications & Clinical Uses

Iopamiro (iopamidol) is a nonionic iodinated contrast agent used in radiographic imaging procedures to enhance visualization of vascular and tissue structures.

  • Angiography: improves visualization of blood vessels and arterial anatomy.
  • Computed tomography (CT) imaging: provides high‑contrast detail for cross‑sectional images of organs and tissues.
  • Urography: enhances delineation of the urinary tract, including kidneys, ureters and bladder.
  • Myelography: facilitates clear imaging of the spinal canal and nerve roots.
  • Cardiac catheterization: improves visualization of cardiac chambers and coronary arteries.

How It Works

  • Iopamidol contains iodine atoms that strongly absorb X‑ray photons. When injected into the vascular system, the iodine increases the radiodensity of blood and surrounding structures, creating a contrast difference that imaging equipment can detect. This heightened attenuation produces detailed images of anatomical features, facilitating diagnosis and interventional guidance while the nonionic, low‑osmolality formulation minimizes physiologic disturbance.

Side Effects

Iopamiro may cause a range of adverse reactions, varying from mild to severe.

Common Side Effects

  • Warmth or flushing sensation: transient feeling of heat at injection site.
  • Nausea: mild to moderate upset stomach.
  • Headache: temporary mild headache.
  • Mild urticaria: limited skin itching or hives.

Serious or Rare Side Effects

  • Anaphylaxis: severe allergic reaction requiring immediate medical attention.
  • Acute renal impairment: sudden decrease in kidney function.
  • Severe hypotension: marked drop in blood pressure.
  • Pulmonary edema: fluid accumulation in lungs.

Precautions & Warnings

Before using Iopamiro, clinicians should consider several precautionary measures to minimize risk.

  • Assess renal function: evaluate creatinine clearance or eGFR prior to administration.
  • Review allergy history: confirm no prior severe reactions to iodinated contrast.
  • Monitor thyroid status: avoid use in uncontrolled hyperthyroidism.
  • Adjust in pregnancy: use only if diagnostic benefit outweighs potential fetal risk.
  • Ensure adequate hydration: maintain fluid balance to reduce nephrotoxicity.
  • Store at ambient temperature: keep in original packaging, protect from light and moisture.

Avoid Interactions

Iopamiro can interact with certain medications, affecting safety or efficacy.

Major Interactions (Avoid)

  • Metformin: risk of lactic acidosis if renal function declines after contrast.
  • Thyroid hormone therapy: iodine load may alter hormone levels.
  • Radioactive iodine treatment: iodine contrast can interfere with uptake.
  • Nephrotoxic drugs (e.g., aminoglycosides): combined risk of kidney injury.

Moderate Interactions (Monitor Closely)

  • Diuretics: may exacerbate volume depletion and renal effects.
  • NSAIDs: can affect renal perfusion when used with contrast.
  • Calcium channel blockers: monitor blood pressure changes.
  • ACE inhibitors: consider temporary discontinuation to protect kidneys.

Frequently Asked Questions

Iopamiro is a brand of iopamidol, a nonionic iodinated contrast agent administered intravenously or intra‑arterially to enhance X‑ray based imaging. It is employed in procedures such as angiography, computed tomography (CT), urography, myelography and cardiac catheterisation, allowing clinicians to obtain clearer images of blood vessels, organs and tissues.

Iopamidol contains iodine atoms that strongly absorb X‑ray photons. When injected into the vascular system, the iodine increases the radiodensity of blood and surrounding structures, creating a contrast difference that imaging equipment can detect. This heightened attenuation produces detailed images of anatomical features, facilitating diagnosis and interventional guidance.

The dose of Iopamiro is determined by the prescribing physician based on the specific imaging study, patient weight, renal function and the required level of contrast enhancement. The healthcare professional calculates the appropriate volume and concentration, and administers it under controlled conditions during the procedure.

The safety of Iopamiro during pregnancy or lactation has not been definitively established. It should only be used if the potential diagnostic benefit outweighs any possible risk to the fetus or infant. Clinicians are advised to consider alternative imaging modalities and consult current guidelines before administration to pregnant or nursing patients.

To place an order, submit an enquiry on the Iopamiro product page at gnhindia.com, specifying the required quantity and providing institutional credentials. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional documentation, and then responds with pricing, availability, shipping details (including any cold‑chain requirements) and necessary import paperwork.

Iopamiro (iopamidol) is a low‑osmolality, nonionic iodinated contrast medium, offering a favorable safety profile compared with older high‑osmolality agents that are more likely to cause discomfort and adverse reactions. Compared with other low‑osmolality agents, it provides comparable image quality while reducing the incidence of warmth sensations and mild allergic responses, making it a widely accepted choice for many imaging procedures.

Iopamiro should be stored at ambient temperature, protected from direct sunlight, moisture and freezing. Keep the vial in its original packaging until use, and avoid shaking the solution. Before administration, inspect the container for particulate matter or discoloration, and discard any product that appears compromised or is beyond its expiration date.

Iopamiro is supplied as a sterile solution for injection and is administered intravenously or intra‑arterially by a qualified healthcare professional. The injection is typically performed using a power injector or manual bolus, depending on the imaging protocol. The volume and rate of administration are tailored to the specific procedure and patient characteristics, ensuring optimal contrast enhancement while minimizing risk.

The most serious risks include severe allergic reactions such as anaphylaxis, acute kidney injury especially in patients with pre‑existing renal impairment, and hemodynamic instability like profound hypotension. Rarely, contrast‑induced neurotoxicity or cardiac arrhythmias may occur. Prompt recognition and appropriate emergency management are essential, and patients at high risk should be closely monitored during and after administration.

Iopamiro is contraindicated in patients with a known hypersensitivity to iopamidol or any iodinated contrast media, as well as those with a history of severe anaphylactic reactions to similar agents. It should also be avoided in individuals with uncontrolled hyperthyroidism, severe renal insufficiency, or those who are pregnant unless the diagnostic benefit clearly outweighs potential risks. Clinicians must assess each patient’s medical history before deciding to use the product.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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