Iopidine (Apraclonidine)

Apraclonidine selectively activates alpha‑2 adrenergic receptors in the ciliary body, which reduces the production of aqueous humor and increases uveoscleral outflow, resulting in a net decrease of intra‑ocular pressure.

The dosing regimen for Iopidine is determined by the prescribing clinician based on the patient’s condition and response. Typically, one to two drops are instilled in the affected eye(s) as directed by the eye care professional.

Safety data for apraclonidine in pregnancy and lactation are limited. It should only be used if the potential benefit justifies any potential risk to the fetus or infant, and the decision must be made by the treating physician.

To order Iopidine, submit an enquiry on the product page at gnhindia.com with the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and necessary import documentation.

Iopidine (apraclonidine) is a selective alpha‑2 agonist, whereas many other glaucoma drops are beta‑blockers, prostaglandin analogues, or carbonic anhydrase inhibitors. Apraclonidine primarily reduces aqueous humor production and can be used when other classes are insufficient or contraindicated.

Iopidine should be stored at room temperature, below 25 °C, in its original packaging. Keep the bottle tightly closed, protect it from light and moisture, and discard any solution that appears discolored or contains particles.

Iopidine is applied as an eye drop. The patient should wash hands, tilt the head back, pull down the lower eyelid to form a pocket, and place the prescribed number of drops into the conjunctival sac without touching the bottle tip to the eye.

Serious risks include severe allergic reactions, significant ocular inflammation, systemic hypotension that may cause dizziness or fainting, and, rarely, precipitating acute angle‑closure glaucoma, which requires immediate medical attention.

Iopidine should not be used by patients with known hypersensitivity to apraclonidine or any excipients, and caution is advised in individuals with severe cardiovascular disease, uncontrolled hypertension, or a history of acute angle‑closure glaucoma.