Product image of Iopize (Latanoprost) supplied by GNH India

Iopize

Active Ingredient:
Latanoprost
Origin:
EU

Iopize (Latanoprost)

Latanoprost, the active ingredient in Iopize, is a prostaglandin analog presented as an ophthalmic solution for ocular use. It treats open-angle glaucoma and ocular hypertension in adults.

GNH India supplies Iopize as a licensed, GDP-compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Sifi S.P.A.

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Indications & Clinical Uses

  • Latanoprost is used in the management of ocular conditions that require reduction of intraocular pressure.
  • Open-angle glaucoma: lowers intraocular pressure to prevent optic nerve damage.
  • Ocular hypertension: reduces elevated eye pressure to lower risk of developing glaucoma.
  • Secondary open-angle glaucoma: helps control pressure when other therapies are insufficient.

How It Works

  • Latanoprost is a prostaglandin F2α analog that binds to FP receptors in the ciliary body, promoting remodeling of the extracellular matrix and increasing uveoscleral outflow of aqueous humor, thereby lowering intraocular pressure.

Side Effects

Common Side Effects

  • Ocular hyperemia (eye redness)
  • Increased eyelash length and thickness
  • Iris color darkening
  • Eye irritation or foreign body sensation
  • Blurred vision
  • Mild eye pain

Serious or Rare Side Effects

  • Severe allergic reaction (e.g., angioedema)
  • Uveitis or iritis
  • Corneal edema or macular edema
  • Paradoxical increase in intraocular pressure
  • Infectious keratitis

Precautions & Warnings

  • Precautions should be observed when using Iopize.
  • Pregnancy: safety not established; avoid unless benefit outweighs risk.
  • Breastfeeding: unknown; consider potential risks.
  • Contraindications: active ocular inflammation or infection.
  • Monitoring: intraocular pressure should be measured after initiation.
  • Contact lens use: avoid wearing lenses for at least 15 minutes after instillation.
  • Store at room temperature: keep in original container, protect from light and moisture, and do not freeze.

Avoid Interactions

Iopize may interact with other ocular or systemic agents.

Major Interactions (Avoid)

  • Nonsteroidal anti‑inflammatory eye drops: may reduce efficacy.
  • Systemic prostaglandin inhibitors: may antagonize effect.
  • Concurrent prostaglandin analogs: additive pressure lowering may cause excessive reduction.

Moderate Interactions (Monitor Closely)

  • Beta‑blocker eye drops: additive intraocular pressure reduction.
  • Carbonic anhydrase inhibitor eye drops: additive effect on pressure.
  • Anticholinergic agents: may affect ocular surface tolerance.

Frequently Asked Questions

Iopize is a branded ophthalmic solution containing latanoprost, indicated for reduction of intraocular pressure in patients with open‑angle glaucoma and ocular hypertension. It helps prevent optic nerve damage and visual field loss by facilitating aqueous humor outflow.

Latanoprost is a prostaglandin F2α analog that binds to FP receptors in the ciliary body, stimulating remodeling of the extracellular matrix and increasing uveoscleral outflow of aqueous humor. This enhanced drainage lowers intraocular pressure, the primary therapeutic goal in glaucoma management.

The dosing regimen for Iopize is determined by the prescribing clinician. Typically, one drop is instilled into the affected eye(s) once daily in the evening, but the exact dose and timing should follow the prescriber’s instructions and may be adjusted based on intraocular pressure response.

Safety data for latanoprost in pregnancy and lactation are limited. It is classified as pregnancy category unknown, and use is generally avoided unless the potential benefit justifies the risk. Women who are pregnant, planning pregnancy, or breastfeeding should discuss alternatives with their ophthalmologist.

To request Iopize, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Iopize (latanoprost) belongs to the prostaglandin analog class, which generally offers once‑daily dosing and a strong intraocular pressure‑lowering effect, often greater than beta‑blockers or carbonic anhydrase inhibitors. Compared with other prostaglandin analogs, its efficacy and safety profile are comparable, though individual response may vary.

Iopize should be stored at room temperature, below 25 °C, in its original container. Keep the bottle tightly closed, protect it from light and moisture, and avoid freezing. Do not refrigerate unless specifically instructed by the manufacturer.

Iopize is applied as an eye drop. The patient should wash hands, tilt the head back, pull down the lower eyelid to form a pocket, and place one drop into the conjunctival sac. Close the eye gently and avoid blinking or rubbing for a few minutes. Do not contaminate the tip.

While generally well tolerated, serious adverse events can include severe allergic reactions, uveitis, corneal edema, macular edema, or a paradoxical increase in intraocular pressure. Any sudden eye pain, redness, vision changes, or swelling should prompt immediate medical evaluation.

Iopize is contraindicated in patients with active ocular inflammation or infection, known hypersensitivity to latanoprost or any component of the formulation, and should be used with caution in pregnant or nursing women. Individuals with a history of severe ocular side effects should discuss alternatives with their eye care provider.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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