Product image of Iperplasin (Mepartricin) supplied by GNH India

Iperplasin

Active Ingredient:
Mepartricin
Origin:
EU

Iperplasin (Mepartricin)

Mepartricin, the active ingredient in Iperplasin, is a quinoline derivative presented as an oral tablet for oral use. It treats chronic prostatitis and benign prostatic hyperplasia in adult males.

GNH India supplies Iperplasin as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Laboratório Medinfar - Produtos Farmacêuticos, S.A.

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Indications & Clinical Uses

Mepartricin, marketed as Iperplasin, acts on prostatic inflammation and tissue remodeling.

  • Chronic prostatitis: reduces prostatic inflammation and alleviates associated urinary symptoms.
  • Benign prostatic hyperplasia: diminishes prostatic swelling, improving urinary flow.
  • Prostatic inflammation: limits collagen deposition and fibrotic changes within the gland.

How It Works

  • Mepartricin exerts anti‑inflammatory and anti‑fibrotic actions by modulating cytokine release, inhibiting fibroblast proliferation, and decreasing collagen synthesis in prostatic tissue. These effects lead to reduced stromal edema and fibrosis, thereby improving urinary function in conditions such as chronic prostatitis and benign prostatic hyperplasia.

Side Effects

Common Side Effects

  • Nausea: mild to moderate gastrointestinal upset.
  • Diarrhea: loose stools occurring intermittently.
  • Headache: transient cranial discomfort.
  • Dizziness: occasional light‑headedness.

Serious or Rare Side Effects

  • Allergic reactions: rash, urticaria, or angioedema.
  • Hepatic dysfunction: elevated liver enzymes or jaundice.
  • Severe neutropenia: marked reduction in white blood cells.
  • Anaphylaxis: rapid onset of systemic hypersensitivity.
  • Blood disorders: thrombocytopenia or anemia.

Precautions & Warnings

Before initiating therapy, consider the following precautions:

  • Renal impairment: assess kidney function and adjust if necessary.
  • Hepatic disease: monitor liver enzymes regularly.
  • Pregnancy: avoid use unless potential benefit outweighs risk.
  • Breastfeeding: not recommended due to unknown excretion in milk.
  • Elderly patients: start at lower dose and monitor tolerability.
  • Store at ambient temperature: keep below 25°C, retain in original packaging, and protect from moisture.

Avoid Interactions

Mepartricin may interact with several drug classes.

Major Interactions (Avoid)

  • Anticoagulants: increased risk of bleeding.
  • Non‑steroidal anti‑inflammatory drugs (NSAIDs): heightened gastrointestinal irritation.
  • Immunosuppressants: potential additive immunomodulatory effects.

Moderate Interactions (Monitor Closely)

  • Diuretics: possible alteration of electrolyte balance.
  • Antihypertensives: monitor blood pressure for additive effects.
  • Other urological agents: assess for overlapping pharmacodynamic actions.

Frequently Asked Questions

Iperplasin contains the active ingredient Mepartricin and is indicated for the management of chronic prostatitis and benign prostatic hyperplasia. It helps reduce prostatic inflammation, limit fibrotic tissue formation, and improve urinary flow in adult male patients.

Mepartricin acts by modulating inflammatory pathways within prostatic tissue, decreasing cytokine release, and inhibiting fibroblast activity. This results in reduced collagen deposition and fibrosis, leading to decreased swelling of the prostate and relief of urinary symptoms.

The specific dosage of Iperplasin is determined by the prescribing healthcare professional based on the patient’s condition, severity, and overall health status. Patients should follow the prescriber’s instructions and not alter the dose without medical guidance.

Safety data for Mepartricin in pregnancy and lactation are limited. It is generally advised to avoid use during pregnancy unless the potential benefit justifies the risk, and it is not recommended for breastfeeding mothers because excretion in milk is unknown.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity of Iperplasin. GNH India works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details, and any necessary import documentation.

Iperplasin’s unique anti‑inflammatory and anti‑fibrotic mechanism differentiates it from alpha‑blockers or 5‑alpha‑reductase inhibitors, which primarily target smooth‑muscle tone or hormonal pathways. It may be used as an adjunct or alternative when inflammation and fibrosis are predominant contributors to symptoms.

Iperplasin should be stored at ambient temperature, preferably below 25 °C. Keep the tablets in the original container, protect them from moisture and direct sunlight, and ensure they are out of reach of children.

Iperplasin is administered orally, typically as a tablet taken with water. The exact timing (e.g., with meals or on an empty stomach) should follow the prescribing clinician’s recommendations.

Serious risks, although rare, include severe allergic reactions such as rash, urticaria, or anaphylaxis, hepatic dysfunction indicated by elevated liver enzymes, and hematologic abnormalities like neutropenia or thrombocytopenia. Patients should seek immediate medical attention if any of these occur.

Iperplasin is contraindicated in patients with known hypersensitivity to Mepartricin or any excipients in the formulation. Caution is also advised for individuals with severe liver or kidney impairment, pregnant or breastfeeding women, and those taking medications that may interact significantly without proper monitoring.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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