Product image of Ipertrofan (Mepartricin) supplied by GNH India

Ipertrofan

Active Ingredient:
Mepartricin
Origin:
EU

Ipertrofan (Mepartricin)

Mepartricin, the active ingredient in Ipertrofan, is a macrolide antibiotic presented as an oral tablet for oral use. It exhibits antibacterial and anti‑inflammatory properties and is used primarily in the treatment of chronic prostatitis, chronic pelvic pain syndrome, and other urogenital inflammatory disorders.

GNH India supplies Ipertrofan as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide. The company adheres to stringent quality standards and provides regulatory documentation for global distribution.

Manufacturer / TM Owner

Spa – Società Prodotti Antibiotici S.P.A.

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Indications & Clinical Uses

Ipertrofan (Mepartricin) is used in the management of urogenital inflammatory conditions, particularly chronic prostatitis.

  • Chronic prostatitis: reduces bacterial load and inflammation in the prostate gland
  • Chronic pelvic pain syndrome: alleviates pain and improves urinary symptoms
  • Benign prostatic hyperplasia‑related inflammation: helps control the inflammatory component

How It Works

  • Mepartricin acts by binding to the 50S ribosomal subunit of susceptible bacteria, inhibiting protein synthesis and exerting a bacteriostatic effect. In addition, it modulates immune responses by decreasing pro‑inflammatory cytokine production and stabilizing lysosomal membranes, which contributes to its anti‑inflammatory activity in urogenital tissues.

Side Effects

Common side effects are generally mild and reversible.

Common Side Effects

  • Nausea: mild to moderate stomach upset
  • Diarrhea: loose stools occurring during therapy
  • Abdominal pain: cramping or discomfort in the abdomen
  • Headache: transient head pain
  • Dizziness: light‑headed sensation
  • Taste alteration: metallic or unusual taste perception

Serious or Rare Side Effects

  • Allergic reaction: rash, itching, or swelling
  • Stevens‑Johnson syndrome: severe skin blistering
  • Hepatic dysfunction: elevated liver enzymes
  • Severe neutropenia: markedly reduced white blood cells
  • Anaphylaxis: rapid onset of life‑threatening symptoms

Precautions & Warnings

Before initiating therapy, consider the following precautions.

  • Liver function assessment: evaluate hepatic enzymes prior to use
  • Renal impairment: adjust therapy in patients with severe kidney disease
  • Hypersensitivity: avoid if known allergy to macrolides
  • Concomitant macrolides: do not combine with other macrolide antibiotics
  • Pregnancy and lactation: use only if benefits outweigh potential risks
  • Store below 25°C: keep in the original pack, protect from moisture

Avoid Interactions

Mepartricin may interact with several drug classes; monitoring is advised.

Major Interactions (Avoid)

  • QT‑prolonging agents: increased risk of cardiac arrhythmia
  • Strong CYP3A4 inhibitors (e.g., ketoconazole, clarithromycin): may raise Mepartricin levels
  • Other macrolide antibiotics: additive toxicity risk

Moderate Interactions (Monitor Closely)

  • Warfarin: possible increase in INR, monitor coagulation
  • Statins (e.g., simvastatin): heightened risk of myopathy
  • Antacids containing aluminum or magnesium: may reduce absorption
  • Oral contraceptives: potential reduction in efficacy, advise additional contraception

Frequently Asked Questions

Ipertrofan contains the active ingredient Mepartricin and is primarily used to treat chronic prostatitis, chronic pelvic pain syndrome, and inflammation associated with benign prostatic hyperplasia. It helps reduce bacterial presence and inflammation in the urogenital tract.

Mepartricin belongs to the macrolide class of antibiotics. It binds to the bacterial 50S ribosomal subunit, inhibiting protein synthesis, which limits bacterial growth. Additionally, it modulates the immune response by decreasing pro‑inflammatory cytokines, providing anti‑inflammatory benefits in affected tissues.

The dosage of Ipertrofan is determined by the prescribing healthcare professional based on the patient’s condition, severity, and response to therapy. Patients should follow the exact regimen provided by their prescriber and not adjust the dose on their own.

Safety data for Mepartricin in pregnancy and lactation are limited. It should only be used if the potential benefit to the mother outweighs any possible risk to the fetus or infant. Healthcare providers should discuss individual risks and benefits with the patient.

To request Ipertrofan, submit an enquiry on the product page at gnhindia.com specifying the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Ipertrofan (Mepartricin) offers both antibacterial and anti‑inflammatory actions, whereas many standard antibiotics target only bacterial eradication. Compared with fluoroquinolones, Mepartricin may have a lower risk of tendon toxicity but shares similar gastrointestinal side‑effect profiles. Choice of therapy depends on microbial susceptibility and patient tolerance.

Ipertrofan tablets should be stored below 25 °C in a dry place. Keep the product in its original packaging to protect it from moisture and light. Do not store in bathrooms or near heat sources, and keep out of reach of children.

Ipertrofan is taken orally, usually with a full glass of water. It can be taken with or without food, but consistent administration with respect to meals helps maintain stable absorption. Patients should swallow the tablet whole and not crush or chew it unless directed by a healthcare professional.

Serious risks include severe allergic reactions such as anaphylaxis, Stevens‑Johnson syndrome, hepatic dysfunction, and marked neutropenia. Patients should seek immediate medical attention if they experience rash, fever, jaundice, persistent vomiting, or signs of infection while on therapy.

Ipertrofan should be avoided in individuals with a known hypersensitivity to Mepartricin or other macrolide antibiotics. Patients with severe liver impairment, significant QT‑interval prolongation, or those taking contraindicated medications should not use this product without close medical supervision.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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