Iprafeine (Ibuprofen, Caffeine)

Ibuprofen blocks COX‑1 and COX‑2 enzymes, lowering prostaglandin production and reducing inflammation and pain. Caffeine antagonises adenosine receptors, which not only provides mild central stimulation but also enhances the analgesic effect of ibuprofen, resulting in faster and more pronounced pain relief.

The appropriate dose of Iprafeine is determined by the prescribing healthcare professional based on the individual’s age, weight, and the severity of the pain. Patients should follow the prescriber’s instructions and the product labeling, and should not exceed the recommended amount.

Safety data for the combination of ibuprofen and caffeine during pregnancy or lactation are limited. Women who are pregnant, planning pregnancy, or breastfeeding should consult their healthcare provider before using Iprafeine to weigh potential benefits against risks.

To request Iprafeine, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India supplies hospitals, pharmacies and procurement teams worldwide, and will verify trade or institutional credentials before providing pricing, availability, shipping details and any required import documentation.

Iprafeine combines ibuprofen with caffeine, which can enhance analgesic efficacy and provide a quicker onset of relief compared with ibuprofen alone. The caffeine component may also reduce perceived fatigue, but the combination may increase the risk of caffeine‑related side effects such as insomnia or palpitations.

Iprafeine should be stored below 25 °C, in a dry place away from direct sunlight. Keep the tablets in the original packaging to protect them from moisture and humidity, and keep out of reach of children.

Iprafeine is taken orally. Swallow the tablet whole with a full glass of water, preferably after a meal or with food to minimise gastrointestinal irritation. Do not crush, chew, or split the tablet unless directed by a healthcare professional.

Serious risks include gastrointestinal bleeding or ulcer perforation, severe allergic reactions such as anaphylaxis, acute kidney injury, and rare but severe skin reactions like Stevens‑Johnson syndrome. Patients should seek immediate medical attention if they experience symptoms such as vomiting blood, severe abdominal pain, rash, or swelling of the face and throat.

Iprafeine should not be used by individuals with known hypersensitivity to ibuprofen, other NSAIDs, or caffeine, those with active peptic ulcer disease, severe renal or hepatic impairment, uncontrolled hypertension, or by children under the age recommended on the label. Pregnant women should consult a physician before use.