Product image of Ipramol Steri-Neb (Ipratropium Bromide, Salbutamol) supplied by GNH India

Ipramol Steri-Neb

Active Ingredient:
Ipratropium Bromide, Salbutamol
Origin:
EU

Ipramol Steri-Neb (Ipratropium Bromide, Salbutamol)

Ipratropium bromide and salbutamol, the active ingredients in Ipramol Steri‑Neb, are a combination anticholinergic (muscarinic antagonist) and short‑acting β2‑agonist presented as a nebulizer solution for inhalation use. They are prescribed to relieve bronchoconstriction in asthma, chronic obstructive pulmonary disease and acute bronchospasm in both adult and pediatric patients.

GNH India supplies Ipramol Steri‑Neb as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide. All batches are manufactured under EU GMP standards and undergo rigorous quality testing before distribution.

Manufacturer / TM Owner

Teva B.V

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Indications & Clinical Uses

Ipramol Steri‑Neb, a bronchodilator combination, is used to manage obstructive airway diseases.

  • Asthma: provides rapid bronchodilation to relieve symptoms and improve airflow.
  • Chronic obstructive pulmonary disease (COPD): reduces bronchospasm and enhances lung function during exacerbations.
  • Acute bronchospasm: offers immediate relief of airway constriction in emergency situations.

How It Works

  • Ipratropium bromide blocks muscarinic receptors on airway smooth muscle, inhibiting acetylcholine‑mediated bronchoconstriction, while salbutamol stimulates β2‑adrenergic receptors, increasing intracellular cAMP and causing relaxation of bronchial smooth muscle, together producing additive bronchodilation.

Side Effects

Ipramol Steri‑Neb may cause a range of adverse reactions.

Common Side Effects

  • Dry mouth: reduced salivary secretion.
  • Cough: irritation of the airway.
  • Throat irritation: mild soreness after inhalation.
  • Tremor: fine muscle tremor, especially of the hands.
  • Headache: mild to moderate intensity.
  • Nausea: occasional upset stomach.

Serious or Rare Side Effects

  • Paradoxical bronchospasm: worsening airway narrowing.
  • Angioedema: swelling of face, lips or tongue.
  • Tachycardia: rapid heart rate.
  • Cardiac arrhythmia: irregular heart rhythm.
  • Severe allergic reaction: rash, itching, difficulty breathing.
  • Hyperglycemia: elevated blood glucose levels.

Precautions & Warnings

Before using Ipramol Steri‑Neb, consider the following precautions.

  • Cardiac history: monitor for tachycardia or arrhythmias.
  • Hypersensitivity: avoid if known allergy to ipratropium, salbutamol or formulation excipients.
  • Glaucoma: use with caution as anticholinergic effects may increase intra‑ocular pressure.
  • Diabetes: monitor blood glucose as β2‑agonist can raise levels.
  • Store at room temperature: keep in original container, protect from light and moisture.

Avoid Interactions

Ipramol Steri‑Neb can interact with several medicines.

Major Interactions (Avoid)

  • Beta‑blockers: may diminish bronchodilator effect and precipitate bronchospasm.
  • MAO inhibitors: increased risk of hypertensive episodes with β2‑agonist activity.
  • Tricyclic antidepressants: additive cardiovascular stimulation.

Moderate Interactions (Monitor Closely)

  • Theophylline: heightened risk of tachyarrhythmia.
  • ACE inhibitors: possible increase in cough frequency.
  • Diabetic medications: potential for hyperglycemia.
  • Systemic corticosteroids: may enhance tremor and tachycardia.

Frequently Asked Questions

Ipramol Steri‑Neb is prescribed for the relief of bronchoconstriction in asthma, chronic obstructive pulmonary disease (COPD) and acute bronchospasm. It provides rapid bronchodilation through a combination of anticholinergic and β2‑agonist actions, helping improve airflow and reduce symptoms in these obstructive airway diseases.

Ipratropium bromide blocks muscarinic receptors on airway smooth muscle, preventing acetylcholine‑induced constriction. Salbutamol activates β2‑adrenergic receptors, raising cyclic AMP levels and causing smooth‑muscle relaxation. Together they produce additive bronchodilation, quickly opening narrowed airways.

The dose of Ipramol Steri‑Neb is determined by the prescribing clinician based on the patient’s age, severity of disease, and response to therapy. Healthcare professionals select the appropriate volume and frequency for nebulization according to established treatment guidelines.

Safety data for Ipramol Steri‑Neb in pregnancy and lactation are limited. The product should only be used if the potential benefit justifies any potential risk to the fetus or infant, and the decision should be made by a qualified healthcare provider.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including any cold‑chain requirements) and the necessary import documentation.

Ipramol Steri‑Neb combines an anticholinergic (ipratropium) with a short‑acting β2‑agonist (salbutamol), offering dual mechanisms that can be more effective than single‑agent bronchodilators in certain patients. Compared with monotherapy, the combination may provide faster and more sustained relief of bronchospasm, especially in moderate to severe COPD or acute asthma attacks.

Store Ipramol Steri‑Neb at room temperature, below 25 °C, in the original packaging. Keep the container tightly closed, protect it from moisture, direct sunlight and extreme temperatures to maintain product stability.

Ipramol Steri‑Neb is a nebulizer solution intended for inhalation. The prescribed volume is placed in a compatible nebulizer device, which converts the liquid into an aerosol that the patient inhales through a mouthpiece or mask, following the clinician’s instructions for duration and frequency.

Serious risks include paradoxical bronchospasm, angioedema, significant tachycardia or arrhythmias, severe allergic reactions, and hyperglycemia. Patients should be monitored for these events, and treatment should be discontinued immediately if any serious reaction occurs.

Ipramol Steri‑Neb should be avoided in individuals with a known hypersensitivity to ipratropium, salbutamol, or any formulation excipients. Caution is also advised for patients with narrow‑angle glaucoma, severe cardiac arrhythmias, or uncontrolled hyperthyroidism, and it should be used only under medical supervision.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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