Product image of Ipramol Steri-Neb (Ipratropium Bromide, Salbutamol) supplied by GNH India

Ipramol Steri-Neb

Active Ingredient:
Ipratropium Bromide, Salbutamol
Origin:
EU

Ipramol Steri-Neb (Ipratropium Bromide, Salbutamol)

Ipratropium bromide and salbutamol, the active ingredients in Ipramol Steri-Neb, are bronchodilators presented as a nebulizer solution for inhalation use. They treat bronchospasm associated with chronic obstructive pulmonary disease (COPD) and asthma, providing rapid relief of airway constriction in patients who require inhaled therapy.

GNH India supplies Ipramol Steri-Neb as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Teva B.V

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Indications & Clinical Uses

Ipramol Steri-Neb is a combination bronchodilator used in the respiratory disease pathway to relieve airway narrowing.

  • COPD bronchospasm: improves airflow and reduces dyspnea in chronic obstructive pulmonary disease patients.
  • Asthma bronchospasm: provides rapid bronchodilation during acute asthma attacks.
  • Exercise‑induced bronchospasm: helps prevent airway constriction triggered by physical activity.

How It Works

  • Ipratropium bromide blocks muscarinic receptors on airway smooth muscle, preventing acetylcholine‑mediated bronchoconstriction, while salbutamol stimulates β2‑adrenergic receptors, causing smooth‑muscle relaxation. The dual action yields additive bronchodilation, enhancing airway patency and easing breathing in obstructive lung conditions.

Side Effects

Ipramol Steri-Neb may cause a range of adverse reactions following inhalation.

Common Side Effects

  • Cough or throat irritation
  • Dry mouth or throat
  • Tremor of the hands or limbs
  • Palpitations or mild tachycardia
  • Headache
  • Nausea

Serious or Rare Side Effects

  • Paradoxical bronchospasm
  • Severe tachyarrhythmia
  • Hypotension
  • Allergic reactions such as rash, angioedema, or anaphylaxis
  • Hyperglycemia in susceptible individuals
  • Cardiovascular events (e.g., myocardial ischemia)

Precautions & Warnings

Before using Ipramol Steri-Neb, consider the following safety measures.

  • Cardiac assessment: monitor for tachycardia or arrhythmias, especially in patients with heart disease.
  • Diabetes monitoring: observe blood glucose levels as salbutamol may raise glucose.
  • Thyroid disease: use caution in hyperthyroid patients due to potential tachycardia.
  • Pregnancy and lactation: discuss risks with a healthcare professional; data are limited.
  • Pediatric use: dose and frequency should be determined by a prescriber.
  • Store at ambient temperature: keep the solution below 25 °C, protect from light and moisture, and retain in the original container.

Avoid Interactions

Ipramol Steri-Neb can interact with other medications that affect the cardiovascular or respiratory systems.

Major Interactions (Avoid)

  • Non‑selective β‑blockers: may diminish bronchodilator effect and precipitate bronchospasm.
  • Monoamine oxidase inhibitors (MAOIs): can increase the risk of cardiovascular side effects.

Moderate Interactions (Monitor Closely)

  • Selective β‑blockers: may reduce efficacy of salbutamol.
  • Theophylline: combined use may enhance tachycardia.
  • Other anticholinergic agents: may increase anticholinergic burden.
  • Diuretics: monitor electrolyte balance and blood pressure.

Frequently Asked Questions

Ipramol Steri-Neb is a prescription nebulizer solution that combines ipratropium bromide and salbutamol to provide rapid bronchodilation. It is indicated for the relief of bronchospasm in patients with chronic obstructive pulmonary disease (COPD) and asthma, helping to improve airflow and reduce breathing difficulty.

Ipratropium bromide is an anticholinergic agent that blocks muscarinic receptors on airway smooth muscle. By preventing acetylcholine‑mediated contraction, it reduces bronchoconstriction, allowing the airways to remain open and facilitating easier breathing.

The dosage of Ipramol Steri-Neb is determined by the prescribing clinician based on the patient’s condition, age, and response to therapy. The prescriber will specify the volume of nebulizer solution and frequency of administration appropriate for each individual case.

Safety data for Ipramol Steri-Neb in pregnancy and lactation are limited. Healthcare providers should weigh the potential benefits against any possible risks and discuss these considerations with the patient before initiating therapy.

To order Ipramol Steri-Neb, submit an enquiry on the product page at gnhindia.com, indicating the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details, and any necessary import documentation.

Ipramol Steri-Neb combines an anticholinergic (ipratropium) with a short‑acting β2‑agonist (salbutamol), offering additive bronchodilation. Compared with single‑agent bronchodilators, this combination can achieve faster and more pronounced airway opening, especially in patients who have an incomplete response to either component alone.

Store Ipramol Steri-Neb at ambient temperature, preferably below 25 °C. Keep the container tightly sealed, protect it from direct sunlight, moisture, and extreme temperatures, and retain it in its original packaging until use.

Ipramol Steri-Neb is administered via a nebulizer. The prescribed volume of the solution is placed in the nebulizer cup, connected to a compressor, and inhaled through a mouthpiece or mask until the medication is fully aerosolized, typically taking several minutes per session.

Serious risks include paradoxical bronchospasm, severe tachyarrhythmias, hypotension, and allergic reactions such as anaphylaxis. Patients should be monitored for these events, especially during initial dosing or when used in individuals with underlying cardiac conditions.

Ipramol Steri-Neb is contraindicated in patients with known hypersensitivity to ipratropium bromide, salbutamol, or any component of the formulation. It should also be avoided in individuals with severe narrow‑angle glaucoma or urinary retention without medical supervision.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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