Product image of Ipramol Steri-Neb (Ipratropium Bromide, Salbutamol) supplied by GNH India

Ipramol Steri-Neb

Active Ingredient:
Ipratropium Bromide, Salbutamol
Origin:
EU

Ipramol Steri-Neb (Ipratropium Bromide, Salbutamol)

Ipratropium bromide and salbutamol, the active ingredient in Ipramol Steri-Neb, is a bronchodilator (combination anticholinergic and β2‑adrenergic agonist) presented as an inhalation formulation for inhalation use. It treats bronchospasm associated with asthma, chronic obstructive pulmonary disease (COPD) and acute exacerbations of respiratory disease.

GNH India supplies Ipramol Steri-Neb as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide, ensuring quality and regulatory compliance.

Manufacturer / TM Owner

Teva Nederland B.V.

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Indications & Clinical Uses

Ipramol Steri-Neb, a combination bronchodilator, is used to manage airway obstruction in several respiratory conditions.

  • Asthma: provides rapid relief of bronchospasm and improves airflow.
  • Chronic obstructive pulmonary disease (COPD): reduces bronchoconstriction and enhances breathing capacity.
  • Acute exacerbations of respiratory disease: alleviates worsening symptoms and supports recovery.

How It Works

  • Ipramol Steri-Neb combines ipratropium bromide, a muscarinic antagonist that blocks acetylcholine‑mediated bronchoconstriction, with salbutamol, a selective β2‑adrenergic agonist that stimulates adenylate cyclase, increasing cyclic AMP and relaxing airway smooth muscle. The dual action produces additive bronchodilation, improving ventilation in obstructed airways.

Side Effects

Ipramol Steri-Neb may cause a range of adverse reactions, varying from mild to serious.

Common Side Effects

  • Dry mouth: sensation of reduced saliva.
  • Cough: transient irritation of the airway.
  • Throat irritation: mild discomfort in the throat.
  • Tremor: mild shaking of the hands.
  • Headache: occasional mild headache.

Serious or Rare Side Effects

  • Paradoxical bronchospasm: worsening airway constriction.
  • Tachycardia: rapid heart rate.
  • Hypersensitivity reactions: rash, swelling, or anaphylaxis.
  • Arrhythmias: irregular heart rhythm.
  • Severe hypotension: marked drop in blood pressure.

Precautions & Warnings

When using Ipramol Steri-Neb, consider the following precautions:

  • Assess respiratory status: evaluate severity before initiating therapy.
  • Monitor heart rate: watch for tachycardia especially in patients with cardiac disease.
  • Use with caution in elderly: increased sensitivity to side effects.
  • Avoid in known hypersensitivity: discontinue if allergic reaction occurs.
  • Concomitant β‑agonists: consider additive cardiovascular effects.
  • Store at ambient temperature: keep in original container, protect from moisture and heat.

Avoid Interactions

Ipramol Steri-Neb can interact with several medicines. Review the following groups before prescribing.

Major Interactions (Avoid)

  • Monoamine oxidase inhibitors (MAOIs): may increase risk of cardiovascular events.
  • Tricyclic antidepressants: can potentiate tachycardia.
  • β‑blockers: may reduce bronchodilator efficacy.
  • Diuretics: may enhance hypokalemia risk.
  • Anticholinergic drugs: additive dry mouth.

Moderate Interactions (Monitor Closely)

  • Theophylline: increased risk of arrhythmias.
  • Digoxin: possible increased serum levels.
  • Non‑selective β‑agonists: additive cardiovascular stimulation.
  • Cough suppressants: may mask bronchospasm symptoms.
  • Antihistamines: may increase anticholinergic burden.

Frequently Asked Questions

Ipramol Steri-Neb is a combination inhaled bronchodilator indicated for the relief of bronchospasm in asthma, chronic obstructive pulmonary disease (COPD) and for the management of acute exacerbations of respiratory disease.

Ipratropium bromide acts as a muscarinic antagonist, blocking acetylcholine receptors in the airway smooth muscle. This inhibition reduces cholinergic‑mediated bronchoconstriction, helping to keep the airways open.

The prescribed dose of Ipramol Steri-Neb is determined by the treating clinician based on the patient’s condition, severity, and response to therapy. Patients should follow the specific instructions provided by their healthcare professional.

Safety data for Ipramol Steri-Neb in pregnancy and lactation are limited. Healthcare providers should weigh the potential benefits against possible risks and discuss any concerns with the patient before prescribing.

To request Ipramol Steri-Neb, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Ipramol Steri-Neb combines an anticholinergic (ipratropium) with a β2‑agonist (salbutamol), offering additive bronchodilation. Single‑agent products such as albuterol provide only β2‑agonist activity, while long‑acting agents like tiotropium act solely on muscarinic receptors. The combination can be advantageous for patients needing rapid and sustained airway relief.

Store Ipramol Steri-Neb at ambient temperature, below 25 °C, in its original packaging. Protect the inhaler from moisture, direct sunlight and extreme heat to maintain drug stability and device performance.

Ipramol Steri-Neb is delivered via inhalation. The patient should inhale a measured dose from the device, holding their breath for a few seconds to allow optimal deposition in the lower airways. Proper technique should be demonstrated by a healthcare professional.

Serious adverse events include paradoxical bronchospasm, tachycardia, severe hypotension, arrhythmias and hypersensitivity reactions such as rash, swelling or anaphylaxis. Patients should seek immediate medical attention if any of these symptoms occur.

Ipramol Steri-Neb should be avoided in individuals with known hypersensitivity to ipratropium, salbutamol or any excipients in the formulation. Caution is also advised for patients with severe cardiac disease, uncontrolled hypertension or those taking interacting medications listed under major interactions.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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