Product image of Ipramol Steri-Neb (Ipratropium Bromide, Salbutamol) supplied by GNH India

Ipramol Steri-Neb

Active Ingredient:
Ipratropium Bromide, Salbutamol
Origin:
EU

Ipramol Steri-Neb (Ipratropium Bromide, Salbutamol)

Ipratropium bromide and Salbutamol, the active ingredients in Ipramol Steri‑Neb, are bronchodilators presented as a nebulizer solution for inhalation use. They relieve bronchospasm in patients with asthma, chronic obstructive pulmonary disease (COPD) and acute bronchospasm.

GNH India supplies Ipramol Steri‑Neb as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Norton Healthcare Ltd T/A Ivax Pharmaceuticals Uk

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Indications & Clinical Uses

  • Ipramol Steri‑Neb acts on the respiratory airways to provide bronchodilation in obstructive lung diseases.
  • Asthma: improves airflow and reduces wheezing during acute episodes.
  • COPD: eases chronic bronchoconstriction and enhances exercise tolerance.
  • Acute bronchospasm: rapidly reverses sudden airway narrowing in emergency settings.

How It Works

  • The combination delivers two complementary actions: ipratropium bromide blocks muscarinic receptors on airway smooth muscle, preventing acetylcholine‑mediated constriction, while salbutamol stimulates β2‑adrenergic receptors, causing relaxation of bronchial smooth muscle. Together they produce additive bronchodilation and improve ventilation.

Side Effects

Adverse reactions may occur with inhalation of the nebulizer solution.

Common Side Effects

  • Dry mouth
  • Cough or throat irritation
  • Tremor
  • Headache
  • Palpitations
  • Nausea

Serious or Rare Side Effects

  • Paradoxical bronchospasm
  • Severe tachycardia or arrhythmia
  • Angioedema
  • Hypotension
  • Acute respiratory distress
  • Anaphylactic reaction

Precautions & Warnings

  • Use Ipramol Steri‑Neb with careful clinical assessment and monitoring.
  • Assess cardiac status: patients with arrhythmias may need closer observation.
  • Monitor for paradoxical bronchospasm: discontinue if symptoms worsen.
  • Use cautiously in urinary retention or narrow‑angle glaucoma.
  • Avoid in known hypersensitivity to ipratropium, salbutamol, or formulation excipients.
  • Store at room temperature: keep in the original container, protect from light and moisture.

Avoid Interactions

Ipramol Steri‑Neb may interact with other medications that affect the cardiovascular or respiratory systems.

Major Interactions (Avoid)

  • Non‑selective β‑blockers: can diminish bronchodilator effect.
  • High‑dose β‑agonist combinations: increase risk of tachycardia and arrhythmia.
  • Anticholinergic agents: may enhance anticholinergic side effects.

Moderate Interactions (Monitor Closely)

  • Theophylline: additive stimulant effect on the heart.
  • Diuretics causing hypokalemia: may potentiate salbutamol‑induced cardiac effects.
  • ACE inhibitors: monitor for cough or bronchospasm exacerbation.

Frequently Asked Questions

Ipramol Steri‑Neb is a prescription nebulizer solution that combines ipratropium bromide and salbutamol to provide bronchodilation. It is used to treat asthma, chronic obstructive pulmonary disease (COPD), and acute bronchospasm by relaxing airway smooth muscle and improving airflow.

Ipratropium bromide blocks muscarinic receptors, preventing acetylcholine‑induced bronchoconstriction, while salbutamol activates β2‑adrenergic receptors, causing smooth‑muscle relaxation. The dual mechanism produces additive bronchodilation, quickly opening narrowed airways in obstructive lung conditions.

The prescribed dose is determined by the treating clinician based on the patient’s age, disease severity, and response to therapy. The prescriber selects the volume of nebulizer solution and frequency of administration that best manages the individual’s respiratory symptoms.

Safety data in pregnancy and lactation are limited. The product should be used only if the potential benefit justifies any possible risk to the fetus or infant. Clinicians should discuss individual circumstances and consider alternative therapies when appropriate.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including any cold‑chain requirements), and import documentation.

Compared with a nebulized salbutamol alone, Ipramol Steri‑Neb adds ipratropium’s anticholinergic effect, offering broader bronchodilation and potentially better symptom control in severe asthma or COPD. The combination may reduce the need for higher doses of a single agent and improve overall lung function.

Store the nebulizer solution at room temperature, preferably below 25 °C. Keep it in the original container, protect it from light, moisture, and extreme temperatures. Do not freeze the product, and discard any solution that appears discolored or contains particles.

The solution is added to a compatible nebulizer cup according to the prescribed volume, then connected to a nebulizer device. The patient inhales the aerosolized medication through a mouthpiece or mask, typically for several minutes until the dose is fully delivered.

Serious adverse events include paradoxical bronchospasm, severe tachycardia or arrhythmias, angioedema, and anaphylactic reactions. Patients should seek immediate medical attention if they experience worsening breathing, rapid heartbeat, swelling of the face or throat, or any signs of an allergic reaction.

The product is contraindicated in individuals with known hypersensitivity to ipratropium, salbutamol, or any excipients in the formulation. It should also be avoided in patients with narrow‑angle glaucoma, severe urinary retention, or those for whom β2‑agonists are medically prohibited.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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