Product image of Ipratropium Adultes Aguettant (Ipratropium Bromide) supplied by GNH India

Ipratropium Adultes Aguettant

Active Ingredient:
Ipratropium Bromide
Origin:
EU

Ipratropium Adultes Aguettant (Ipratropium Bromide)

Ipratropium Bromide, the active ingredient in Ipratropium Adultes Aguettant, is an anticholinergic (muscarinic antagonist) presented as an inhalation solution for inhalation use. It provides bronchodilation for adults with chronic obstructive pulmonary disease (COPD) and asthma.

GNH India supplies Ipratropium Adultes Aguettant as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Laboratoire Aguettant

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Indications & Clinical Uses

Ipratropium Bromide is used to manage airway obstruction in chronic respiratory diseases.

  • Chronic obstructive pulmonary disease (COPD): improves airflow and reduces exacerbations.
  • Asthma: provides bronchodilation as an add‑on maintenance therapy.
  • Bronchospasm: relieves acute bronchospasm associated with COPD or asthma.

How It Works

  • Ipratropium Bromide acts as a competitive antagonist at muscarinic (M3) receptors on airway smooth muscle. By blocking acetylcholine‑mediated bronchoconstriction, it promotes relaxation of the bronchial smooth muscle, leading to increased airway diameter and improved ventilation in patients with obstructive lung disease.

Side Effects

Common Side Effects

  • Dry mouth: reduced salivary secretion.
  • Cough: irritation of the airway.
  • Throat irritation: mild soreness after inhalation.
  • Headache: transient discomfort.
  • Dizziness: occasional light‑headedness.
  • Nausea: mild gastrointestinal upset.

Serious or Rare Side Effects

  • Paradoxical bronchospasm: sudden worsening of breathing.
  • Angioedema: swelling of lips, tongue or face.
  • Severe allergic reaction: rash, hives, or anaphylaxis.
  • Tachycardia: rapid heart rate.
  • Urinary retention: difficulty emptying the bladder.
  • Vision changes: blurred vision or increased intra‑ocular pressure.

Precautions & Warnings

Before initiating therapy, evaluate the patient's respiratory diagnosis and assess for contraindications.

  • Assess respiratory status: confirm COPD or asthma diagnosis before use.
  • Monitor anticholinergic effects: watch for dry mouth, urinary retention, or glaucoma exacerbation.
  • Avoid in patients with hypersensitivity to ipratropium or atropine derivatives.
  • Use with caution in narrow‑angle glaucoma or prostatic hypertrophy.
  • Store at room temperature: keep in original container, protect from moisture and heat.

Avoid Interactions

Ipratropium may interact with other medications that affect the cholinergic system or bronchodilation.

Major Interactions (Avoid)

  • Concurrent use with other muscarinic antagonists (e.g., tiotropium): risk of additive anticholinergic effects.
  • Co‑administration with cholinesterase inhibitors (e.g., pyridostigmine): may reduce therapeutic benefit.

Moderate Interactions (Monitor Closely):\n- Beta‑agonists (e.g., albuterol): monitor for additive bronchodilation and tremor.

  • Theophylline: observe for altered plasma levels.
  • Inhaled corticosteroids: increased risk of oral thrush; advise proper mouth rinsing.

Frequently Asked Questions

Ipratropium Adultes Aguettant contains ipratropium bromide, an anticholinergic bronchodilator prescribed to relieve airway narrowing in adults with chronic obstructive pulmonary disease (COPD) and asthma. It helps improve breathing by relaxing the smooth muscle of the airways.

Ipratropium bromide blocks muscarinic (M3) receptors on airway smooth muscle, preventing acetylcholine‑induced bronchoconstriction. This competitive antagonism leads to relaxation of the bronchial muscles, widening the airways and facilitating better airflow in obstructive lung conditions.

The dosage of Ipratropium Adultes Aguettant is determined by the prescribing clinician based on the patient’s condition, severity, and response to therapy. The prescriber will specify the number of inhalations and frequency according to approved guidelines.

Safety data for ipratropium bromide in pregnancy and lactation are limited, and the product is classified as pregnancy category unknown. It should only be used if the potential benefit justifies any potential risk to the fetus or infant, and under medical supervision.

To place an order, submit an enquiry on the product page at gnhindia.com, providing the required quantity. GNH India supplies hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then replies with pricing, availability, shipping details and any necessary import documentation.

Ipratropium is an anticholinergic bronchodilator, whereas beta‑agonists (e.g., albuterol) act on adrenergic receptors. Ipratropium provides a complementary mechanism, often used as add‑on therapy to beta‑agonists for enhanced bronchodilation, especially in patients with COPD who may not respond fully to beta‑agonists alone.

The product should be stored at room temperature, below 25 °C, in its original packaging. Keep it away from moisture, direct sunlight, and heat sources. Ensure the inhalation device is sealed until use to maintain product integrity.

Ipratropium Adultes Aguettant is delivered via inhalation using a nebulizer or metered‑dose inhaler, as directed by the healthcare professional. The patient inhales the prescribed number of puffs or nebulized dose, typically spaced according to the prescribed schedule.

Serious risks include paradoxical bronchospasm, which can worsen breathing, and rare allergic reactions such as angioedema or anaphylaxis. Patients should be monitored for sudden respiratory distress, facial swelling, or severe skin reactions and seek immediate medical attention if these occur.

Patients with known hypersensitivity to ipratropium bromide, atropine, or any component of the formulation should avoid this product. Caution is also advised for individuals with narrow‑angle glaucoma, urinary retention, or severe prostatic hypertrophy, as anticholinergic effects may exacerbate these conditions.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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