Product image of Ipratropium Bromide/Salbutamol Neutec (Ipratropium Bromide, Salbutamol) supplied by GNH India

Ipratropium Bromide/Salbutamol Neutec

Active Ingredient:
Ipratropium Bromide, Salbutamol
Origin:
EU

Ipratropium Bromide/Salbutamol Neutec (Ipratropium Bromide, Salbutamol)

Ipratropium bromide, the active ingredient in Ipratropium Bromide/Salbutamol Neutec, is a combination bronchodilator presented as an inhalation formulation for inhalation use. It treats asthma and chronic obstructive pulmonary disease (COPD) in adults.\nGNH India supplies Ipratropium Bromide/Salbutamol Neutec as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Neutec Inhaler Ireland Ltd

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Indications & Clinical Uses

  • Ipratropium bromide and salbutamol act on the airways to provide bronchodilation for obstructive lung diseases.\n\nAsthma: rapid relief of bronchoconstriction and improvement of airflow.\nCOPD: enhances bronchodilation to reduce symptoms and exacerbations.\nAcute bronchospasm: provides prompt bronchodilation during sudden airway narrowing.

How It Works

  • Ipratropium bromide blocks muscarinic receptors in airway smooth muscle, preventing acetylcholine‑mediated bronchoconstriction, while salbutamol selectively stimulates β2‑adrenergic receptors, increasing cyclic AMP and causing smooth‑muscle relaxation. The combined actions result in additive bronchodilation and improved airway patency.

Side Effects

  • The following adverse reactions have been reported with the combination inhaler.\n\nCommon Side Effects:\n- Dry mouth\n- Cough or throat irritation\n- Tremor\n- Headache\n\nSerious or Rare Side Effects:\n- Paradoxical bronchospasm\n- Angioedema or severe hypersensitivity\n- Tachycardia or arrhythmia\n- Significant hypertension

Precautions & Warnings

  • Before prescribing, clinicians should consider several safety aspects.\n\nAssess cardiac status: monitor for tachyarrhythmias in patients with heart disease.\nMonitor for paradoxical bronchospasm: discontinue if severe wheezing occurs.\nUse with caution in narrow‑angle glaucoma: anticholinergic effect may increase intra‑ocular pressure.\nAvoid in patients with known hypersensitivity to either component.\nStore at room temperature: keep in original container, protect from moisture and direct sunlight.

Avoid Interactions

  • Ipratropium bromide/salbutamol may interact with other medications affecting the cardiovascular or respiratory systems.\n\nMajor Interactions (Avoid):\n- Non‑selective β‑blockers: may diminish bronchodilator effect.\n- MAO inhibitors or tricyclic antidepressants: increase risk of cardiovascular side effects.\n- Diuretics: may exacerbate hypokalemia when combined with β2‑agonists.\n\nModerate Interactions (Monitor Closely):\n- Theophylline: additive bronchodilator effect may increase toxicity.\n- Other inhaled bronchodilators: monitor for cumulative cardiovascular stimulation.

Frequently Asked Questions

Ipratropium Bromide/Salbutamol Neutec is a prescription inhalation product that combines an anticholinergic and a β2‑agonist to provide bronchodilation. It is indicated for the treatment of asthma and chronic obstructive pulmonary disease (COPD) to relieve bronchospasm and improve airflow.

Ipratropium bromide blocks muscarinic receptors, preventing acetylcholine‑induced bronchoconstriction, while salbutamol activates β2‑adrenergic receptors, increasing cyclic AMP and relaxing airway smooth muscle. The dual mechanism produces additive bronchodilation, enhancing symptom control.

The prescribed dose is determined by the treating physician based on the patient’s clinical condition, severity of disease, and response to therapy. The prescriber will specify the number of inhalations and frequency according to approved labeling.

Safety data in pregnancy and lactation are limited. The product should be used only if the potential benefit justifies the potential risk to the fetus or infant, and the decision should be made by a healthcare professional.

To place an order, submit an enquiry on the product page at gnhindia.com, providing the required quantity. GNH India supplies hospitals, pharmacies and procurement teams worldwide, and will request trade or institutional credentials before responding with pricing, availability, shipping details and import documentation.

Compared with single‑agent inhalers, the combination offers additive bronchodilation, potentially improving symptom control in patients who need both anticholinergic and β2‑agonist effects. It may reduce the need for multiple inhalers, but individual response and tolerance should be evaluated by the prescriber.

Store the inhaler at room temperature, below 25 °C, in its original packaging. Protect it from moisture, heat and direct sunlight to maintain product stability.

The medication is delivered via inhalation using a metered‑dose inhaler or nebulizer, as directed by the prescribing clinician. Patients should follow the inhalation technique instructions provided with the device to ensure optimal drug delivery.

Serious adverse events include paradoxical bronchospasm, angioedema, severe tachycardia or arrhythmias, and significant hypertension. Patients should seek immediate medical attention if they experience any of these reactions.

The product is contraindicated in individuals with known hypersensitivity to ipratropium, salbutamol, or any excipients in the formulation. It should also be avoided in patients with narrow‑angle glaucoma or urinary retention unless specifically advised by a physician.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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