Product image of Ipratropium + Fenoterol Farmak (Fenoterol Hydrobromide, Ipratropium Bromide Anhydrous) supplied by GNH India

Ipratropium + Fenoterol Farmak

Active Ingredient:
Fenoterol Hydrobromide, Ipratropium Bromide Anhydrous
Origin:
EU

Ipratropium + Fenoterol Farmak (Fenoterol Hydrobromide, Ipratropium Bromide Anhydrous)

Fenoterol Hydrobromide, the active ingredient in Ipratropium + Fenoterol Farmak, is a β2‑adrenergic agonist presented as an inhalation bronchodilator for the relief of bronchospasm in asthma and chronic obstructive pulmonary disease. Ipratropium Bromide, also contained in the product, adds anticholinergic activity to enhance airway opening.
GNH India supplies Ipratropium + Fenoterol Farmak as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Farmak International Sp. Z O.O.

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Indications & Clinical Uses

  • Ipratropium + Fenoterol Farmak is a fixed‑dose inhaled bronchodilator used in obstructive airway diseases.
  • Asthma: improves airflow by relaxing bronchial smooth muscle and reducing cholinergic tone.
  • Chronic obstructive pulmonary disease (COPD): provides rapid relief of bronchoconstriction and improves exercise tolerance.
  • Bronchospasm (acute): rapidly alleviates sudden airway narrowing during attacks.

How It Works

  • Fenoterol stimulates β2‑adrenergic receptors on airway smooth muscle, increasing cyclic AMP and causing bronchodilation. Ipratropium blocks muscarinic M3 receptors, preventing acetylcholine‑mediated bronchoconstriction. The combined action produces synergistic relaxation of airway smooth muscle, enhancing airflow and reducing resistance in obstructive lung conditions.

Side Effects

The following adverse reactions have been reported with inhaled fenoterol/ipratropium combinations.

Common Side Effects

  • Cough or throat irritation.
  • Dry mouth.
  • Headache.
  • Tremor or shakiness.
  • Palpitations.
  • Nausea.

Serious or Rare Side Effects

  • Paradoxical bronchospasm.
  • Cardiac arrhythmias.
  • Severe allergic reactions (anaphylaxis, angioedema).
  • Hyperglycemia in susceptible patients.
  • Acute urinary retention (in patients with prostatic hypertrophy).

Precautions & Warnings

  • Before using Ipratropium + Fenoterol Farmak, consider the following safety points.
  • Avoid use in patients with known hypersensitivity to either component.
  • Monitor cardiac status in patients with arrhythmias or coronary disease.
  • Use caution in patients with uncontrolled diabetes, as β2‑agonists may raise blood glucose.
  • Assess for urinary retention risk in men with prostate enlargement.
  • Do not exceed prescribed frequency; overuse can increase systemic exposure.
  • Store at ambient temperature: keep in original container, protect from moisture and direct sunlight.

Avoid Interactions

Ipratropium + Fenoterol Farmak may interact with several medication classes.

Major Interactions (Avoid)

  • Non‑selective β‑blockers: may blunt bronchodilator effect and precipitate bronchospasm.
  • Monoamine oxidase inhibitors (MAOIs) or tricyclic antidepressants: risk of severe hypertension.
  • Potassium‑sparing diuretics (e.g., spironolactone): may increase risk of hyperkalemia when combined with β2‑agonists.

Moderate Interactions (Monitor Closely):\n- Diuretics (e.g., furosemide): may enhance hypokalemia.

  • Theophylline: additive stimulant effect on the heart.
  • Anticholinergic drugs (e.g., atropine): may increase anticholinergic side effects.
  • Corticosteroids: monitor for increased risk of oral thrush when used together.

Frequently Asked Questions

Ipratropium + Fenoterol Farmak is prescribed to treat bronchospasm associated with asthma, chronic obstructive pulmonary disease (COPD), and acute episodes of airway narrowing. The combination provides rapid bronchodilation by targeting both β2‑adrenergic and muscarinic pathways, helping patients regain normal breathing during flare‑ups.

Fenoterol is a selective β2‑adrenergic agonist. When inhaled, it binds to β2 receptors on airway smooth muscle, stimulating adenylate cyclase, raising cyclic AMP levels, and causing muscle relaxation. This results in widened airways and improved airflow, especially during an asthma or COPD exacerbation.

The specific dose and frequency are determined by the prescribing clinician based on the patient’s severity of disease, age, and response to therapy. Healthcare professionals tailor the inhalation regimen to achieve optimal bronchodilation while minimizing side effects.

Safety data for this combination in pregnancy and lactation are limited. It should only be used if the potential benefit justifies any potential risk to the fetus or infant, and the decision must be made by a qualified healthcare provider after a thorough risk‑benefit assessment.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details, and any necessary import documentation.

Compared with other fixed‑dose inhalers such as salbutamol‑ipratropium, fenoterol‑ipratropium offers a slightly longer β2‑agonist action and may provide enhanced bronchodilation in some patients. Choice of therapy depends on individual response, physician preference, and local formulary guidelines.

Store the inhaler at ambient temperature, preferably below 25 °C. Keep it in the original packaging, protect it from moisture and direct sunlight, and ensure the cap is securely closed when not in use to maintain dose integrity.

The medication is delivered via a metered‑dose inhaler (MDI) or nebulizer, as directed by the prescriber. Patients should inhale the prescribed number of puffs or nebulized doses, exhale fully before inhalation, and hold their breath for a few seconds to allow optimal drug deposition in the lungs.

Serious adverse events include paradoxical bronchospasm, severe cardiac arrhythmias, and anaphylactic reactions. Patients should seek immediate medical attention if they experience sudden worsening of breathing, chest pain, palpitations, or signs of an allergic reaction such as swelling of the face or throat.

Individuals with a known hypersensitivity to fenoterol, ipratropium, or any excipients in the formulation should avoid this product. It is also contraindicated in patients with acute narrow‑angle glaucoma or urinary retention due to prostate enlargement, unless specifically advised by a physician.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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