Product image of Ipratropiumbromid+fenoterolhydrobromid Farmak (Fenoterol Hydrobromide, Ipratropium Bromide Anhydrous) supplied by GNH India

Ipratropiumbromid+fenoterolhydrobromid Farmak

Active Ingredient:
Fenoterol Hydrobromide, Ipratropium Bromide Anhydrous
Origin:
EU

Ipratropiumbromid+fenoterolhydrobromid Farmak (Fenoterol Hydrobromide, Ipratropium Bromide Anhydrous)

Ipratropium bromide / Fenoterol hydrobromide, the active ingredient in Ipratropiumbromid+fenoterolhydrobromid Farmak, is an anticholinergic bronchodilator and short‑acting β2‑agonist presented as an inhalation solution for inhalation use. It provides bronchodilation for patients with asthma and chronic obstructive pulmonary disease.

GNH India supplies Ipratropiumbromid+fenoterolhydrobromid Farmak as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Farmak International Sp. Z O.O.

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Indications & Clinical Uses

Ipratropium bromide / Fenoterol hydrobromide acts on the airway smooth muscle to improve airflow in obstructive lung diseases.

  • Asthma: improves airway opening and reduces wheezing, shortness of breath and rescue medication use.
  • Chronic obstructive pulmonary disease (COPD): enhances airflow, decreases dyspnea and helps prevent exacerbations.
  • Acute bronchospasm: provides rapid bronchodilation for relief of sudden airway constriction.

How It Works

  • Ipratropium bromide blocks muscarinic receptors on airway smooth muscle, preventing acetylcholine‑mediated bronchoconstriction, while fenoterol hydrobromide selectively stimulates β2‑adrenergic receptors, increasing cyclic AMP and causing relaxation of bronchial smooth muscle. The combined action results in additive bronchodilation and improved ventilation in obstructive airway conditions.

Side Effects

The following adverse reactions have been reported with the combined inhalation solution.

Common Side Effects

  • Dry mouth: reduced salivary secretion.
  • Cough or throat irritation: local irritation from the aerosol.
  • Headache: mild to moderate intensity.
  • Tremor: fine muscle tremor, often transient.
  • Palpitations: awareness of heartbeat.
  • Nausea: occasional upset stomach.

Serious or Rare Side Effects

  • Paradoxical bronchospasm: worsening airway constriction after inhalation.
  • Angioedema: swelling of face, lips or tongue.
  • Severe tachyarrhythmia: rapid heart rhythm requiring medical attention.
  • Anaphylactic reaction: systemic allergic response with hypotension and airway compromise.

Precautions & Warnings

Before prescribing the inhalation solution, clinicians should consider the following safety measures.

  • Assess renal function: adjust therapy in severe impairment.
  • Monitor heart rate: watch for tachycardia or arrhythmias.
  • Avoid use in patients with known hypersensitivity to either component.
  • Use with caution in cardiovascular disease: may increase heart workload.
  • Pregnancy and lactation: consult a physician as safety data are limited.
  • Store at room temperature: keep in original container, protect from moisture and light.

Avoid Interactions

Potential drug interactions should be reviewed prior to initiating therapy.

Major Interactions (Avoid)

  • Beta‑blockers: may blunt bronchodilator effect.
  • Monoamine oxidase inhibitors (MAOIs): risk of hypertensive crisis with fenoterol.
  • Concurrent anticholinergics: may increase anticholinergic side effects.

Moderate Interactions (Monitor Closely)

  • Diuretics: may potentiate hypokalemia.
  • Theophylline: increased risk of tachyarrhythmia.
  • Systemic corticosteroids: may enhance systemic adrenergic effects.

Frequently Asked Questions

Ipratropiumbromid+fenoterolhydrobromid Farmak is a prescription inhalation solution that provides bronchodilation for patients with asthma and chronic obstructive pulmonary disease (COPD). The combination of an anticholinergic and a short‑acting β2‑agonist helps open the airways, relieve wheezing and improve breathing during acute episodes or as part of maintenance therapy.

Ipratropium bromide blocks muscarinic receptors, preventing acetylcholine‑induced bronchoconstriction, while fenoterol hydrobromide activates β2‑adrenergic receptors, increasing cyclic AMP and causing smooth‑muscle relaxation. Together they produce additive bronchodilation, rapidly improving airflow in obstructive lung conditions.

The prescribed dose of Ipratropiumbromid+fenoterolhydrobromid Farmak is determined by the treating physician based on the patient’s age, severity of disease and response to therapy. Dosage instructions are provided on the prescription label and should be followed exactly as directed by the healthcare professional.

Safety data for ipratropium bromide and fenoterol hydrobromide during pregnancy and lactation are limited. The drug should be used only if the potential benefit justifies any potential risk to the fetus or infant, and the decision should be made in consultation with a qualified healthcare provider.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India supplies hospitals, pharmacies and procurement teams worldwide, and will request verification of trade or institutional credentials. After confirmation, the team provides pricing, availability, shipping details (including any cold‑chain requirements) and assists with import documentation.

The ipratropium‑fenoterol combination offers dual mechanisms—anticholinergic and β2‑agonist—in a single inhalation solution, providing broader bronchodilation than either agent alone. Compared with single‑component inhalers, the combo may reduce the number of devices a patient needs, potentially improving adherence while delivering rapid symptom relief.

Store the inhalation solution at room temperature, below 25 °C, in its original packaging. Keep the container tightly closed, protect it from moisture and direct sunlight, and avoid freezing. Follow any additional handling instructions on the label to maintain product stability.

The product is supplied as an inhalation solution intended for use with a compatible nebulizer or inhalation device. The patient inhales the aerosolized medication as directed by the prescriber, typically multiple times per day or during acute episodes, ensuring the mouthpiece is clean and the device is operated according to the manufacturer’s guidelines.

Serious adverse reactions, although rare, include paradoxical bronchospasm, angioedema, severe tachyarrhythmia and anaphylactic reactions. Patients should seek immediate medical attention if they experience sudden worsening of breathing, swelling of the face or throat, rapid heart rate, or signs of an allergic reaction.

The medication is contraindicated in individuals with known hypersensitivity to ipratropium bromide, fenoterol hydrobromide, or any excipients in the formulation. It should also be avoided in patients with a history of severe paradoxical bronchospasm or those for whom β2‑agonists are contraindicated, such as certain cardiac arrhythmia conditions, unless specifically advised by a physician.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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