Product image of Ipratropiumbromid/Salbutamol Neutec (Ipratropium Bromide, Salbutamol) supplied by GNH India

Ipratropiumbromid/Salbutamol Neutec

Active Ingredient:
Ipratropium Bromide, Salbutamol
Origin:
EU

Ipratropiumbromid/Salbutamol Neutec (Ipratropium Bromide, Salbutamol)

Ipratropium bromide, the active ingredient in Ipratropiumbromid/Salbutamol Neutec, is a bronchodilator presented as a combination formulation with salbutamol for inhalation use. It works to open narrowed airways, providing relief in chronic obstructive pulmonary disease (COPD) and asthma by reducing bronchoconstriction and improving airflow.

GNH India supplies Ipratropiumbromid/Salbutamol Neutec as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Neutec Inhaler Ireland Ltd

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Indications & Clinical Uses

  • Ipratropium bromide/Salbutamol is a dual bronchodilator used in respiratory disorders that cause airway narrowing.
  • COPD: Improves airflow and reduces breathlessness in chronic obstructive pulmonary disease.
  • Asthma: Provides rapid relief of bronchospasm in asthma patients.
  • Acute bronchospasm: Relieves sudden airway constriction during exacerbations.

How It Works

  • The combination contains ipratropium bromide, a muscarinic antagonist that blocks acetylcholine‑mediated bronchoconstrictor reflexes, and salbutamol, a short‑acting β2‑adrenergic agonist that stimulates adenylate cyclase, increasing cyclic AMP and relaxing airway smooth muscle, resulting in bronchodilation.

Side Effects

The medication may cause a range of adverse reactions, from mild to severe.

Common Side Effects

  • Dry mouth or throat irritation
  • Cough or hoarseness after inhalation
  • Tremor of the hands or muscles
  • Headache
  • Palpitations or mild tachycardia
  • Nausea

Serious or Rare Side Effects

  • Paradoxical bronchospasm (worsening of breathing difficulty)
  • Severe tachyarrhythmias or cardiac rhythm disturbances
  • Angioedema or severe allergic reactions
  • Hyperglycemia, especially in diabetic patients
  • Hypokalemia (low blood potassium levels)

Precautions & Warnings

  • Before using this inhalation product, consider the following safety measures.
  • Hypersensitivity: Avoid if the patient has known allergy to ipratropium, salbutamol or any excipients.
  • Cardiovascular disease: Use with caution in patients with arrhythmias, hypertension or coronary artery disease.
  • Diabetes: Monitor blood glucose as salbutamol may raise glucose levels.
  • Pregnancy and lactation: Use only if the potential benefit outweighs the risk; consult a healthcare professional.
  • Store at room temperature: Keep in the original container, protect from moisture and light.

Avoid Interactions

Drug interactions may alter the efficacy or safety of the combination inhaler.

Major Interactions (Avoid)

  • Non‑selective beta‑blockers: May diminish bronchodilator effect and precipitate bronchospasm.
  • Monoamine oxidase inhibitors (MAOIs): Potential for exaggerated cardiovascular effects.

Moderate Interactions (Monitor Closely):\n- Theophylline: May increase risk of tachycardia and tremor.

  • Diabetic medications: Salbutamol can raise blood glucose, requiring dose adjustments.
  • Systemic corticosteroids: May enhance risk of hypokalemia when used together.

Frequently Asked Questions

Ipratropiumbromid/Salbutamol Neutec is prescribed for chronic obstructive pulmonary disease (COPD) and asthma. It helps open narrowed airways, providing relief from breathlessness and wheezing during stable disease or acute exacerbations.

Ipratropium bromide blocks muscarinic receptors, preventing acetylcholine‑induced bronchoconstriction, while salbutamol stimulates β2‑adrenergic receptors, increasing cyclic AMP and relaxing airway smooth muscle. Together they produce additive bronchodilation.

The prescribed dose is determined by the treating physician based on the patient’s severity of disease, response to therapy, and clinical guidelines. Dosage instructions are provided on the prescription label.

Safety in pregnancy and lactation has not been fully established. The medication should only be used if the potential benefit justifies any possible risk to the fetus or infant, and under the guidance of a healthcare professional.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and necessary import documentation.

Compared with single‑agent bronchodilators, the combination offers dual mechanisms—anticholinergic and β2‑agonist—providing greater bronchodilation and symptom control, especially in patients who need both pathways targeted. It is often preferred when monotherapy does not achieve adequate relief.

Store the inhalation product at room temperature, below 25 °C, in its original packaging. Keep it away from moisture, heat sources and direct sunlight to maintain stability and potency.

The medication is delivered via a metered‑dose inhaler or nebulizer, as directed by the prescriber. The patient inhales the dose deeply, holds the breath briefly, and then exhales, following the specific device instructions.

Serious risks include paradoxical bronchospasm, severe tachyarrhythmias, angioedema, and significant changes in blood glucose or potassium levels. Patients should seek immediate medical attention if they experience worsening breathing, chest pain, swelling of the face or throat, or irregular heartbeats.

Individuals with a known hypersensitivity to ipratropium, salbutamol, or any formulation components should avoid this product. Caution is also advised for patients with certain cardiac conditions, uncontrolled hypertension, or severe diabetes, and it should be used only under medical supervision.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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