Product image of Ipratropiumbromid Stulln (Ipratropium Bromide) supplied by GNH India

Ipratropiumbromid Stulln

Active Ingredient:
Ipratropium Bromide
Origin:
EU

Ipratropiumbromid Stulln (Ipratropium Bromide)

Ipratropium bromide, the active ingredient in Ipratropiumbromid Stulln, is an anticholinergic (muscarinic antagonist) presented as an inhalation formulation for inhalation use. It provides bronchodilation and is indicated for the management of chronic obstructive pulmonary disease and asthma in adult patients.

GNH India supplies Ipratropiumbromid Stulln as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide. The company adheres to stringent quality standards and provides reliable logistics for global distribution. Customers benefit from comprehensive regulatory support and consistent product availability across regions.

Manufacturer / TM Owner

Penta Arzneimittel Gmbh

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Indications & Clinical Uses

  • Ipratropium bromide is a bronchodilator that acts on the muscarinic receptors of the airways.
  • Chronic obstructive pulmonary disease: improves airflow and reduces the frequency of exacerbations.
  • Asthma: provides additional bronchodilation as add‑on therapy for patients inadequately controlled with other agents.
  • Bronchospasm: relieves acute bronchoconstriction associated with irritant exposure or exercise.

How It Works

  • Ipratropium bromide acts as a competitive antagonist at muscarinic (M3) acetylcholine receptors located on airway smooth muscle. By blocking the action of acetylcholine, it prevents bronchoconstriction, leading to relaxation of the bronchial smooth muscle and improved airflow in the respiratory tract.

Side Effects

Ipratropium bromide may cause adverse reactions, ranging from mild to severe.

Common Side Effects

  • Dry mouth: reduced salivary secretion causing throat discomfort and difficulty swallowing.
  • Cough: irritation of the airway lining leading to a persistent cough after inhalation.
  • Throat irritation: soreness or burning sensation in the throat shortly after use.
  • Headache: mild to moderate headache occurring within hours of administration.

Serious or Rare Side Effects

  • Urinary retention: difficulty emptying the bladder, particularly in patients with pre‑existing prostate enlargement.
  • Glaucoma exacerbation: increased intra‑ocular pressure in individuals with narrow‑angle glaucoma, potentially leading to vision loss.
  • Severe allergic reaction: signs include rash, swelling, wheezing, or anaphylaxis requiring immediate medical attention.

Precautions & Warnings

Before using Ipratropium bromide, consider the following precautions:

  • Assess renal function: use with caution in patients with severe renal impairment.
  • Monitor anticholinergic effects: watch for dry mouth, urinary retention, or constipation.
  • Avoid in narrow‑angle glaucoma: the drug may increase intra‑ocular pressure.
  • Caution in cardiovascular disease: observe for tachycardia or arrhythmias.
  • Store at room temperature: keep in the original container, protect from moisture and light.

Avoid Interactions

Ipratropium bromide can interact with other medications; review the following:

Major Interactions (Avoid)

  • Concurrent use with other inhaled anticholinergics (e.g., tiotropium): may lead to excessive anticholinergic burden.
  • Combination with ophthalmic anticholinergic agents in glaucoma patients: risk of worsening intra‑ocular pressure.

Moderate Interactions (Monitor Closely):\n- Co‑administration with beta‑2 agonists: additive bronchodilation may increase heart rate and cause tremor.

  • Use with drugs that prolong the QT interval: monitor cardiac rhythm for potential arrhythmias.
  • Concomitant antihistamines: may enhance anticholinergic side effects such as dry mouth and constipation.

Frequently Asked Questions

Ipratropiumbromid Stulln is a prescription inhalation product that contains ipratropium bromide, an anticholinergic bronchodilator. It is used to manage chronic obstructive pulmonary disease (COPD) and asthma by helping to open the airways and improve breathing in adult patients.

Ipratropium bromide works by competitively blocking muscarinic (M3) acetylcholine receptors on airway smooth muscle. This inhibition prevents acetylcholine‑mediated bronchoconstriction, leading to relaxation of the bronchial muscles and increased airflow through the lungs.

The specific dose and frequency are determined by the prescribing healthcare professional based on the patient’s condition, severity, and response to therapy. Typical regimens involve inhalation via a nebulizer or metered‑dose inhaler, but the exact dosing must be individualized by the prescriber.

Safety data for ipratropium bromide in pregnancy and lactation are limited. It should only be used if the potential benefit to the mother outweighs any possible risk to the fetus or infant. Consultation with a healthcare provider is essential before use in these populations.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India supplies hospitals, pharmacies, and procurement teams worldwide. The sales team will verify trade or institutional credentials and then provide pricing, availability, shipping details (including any cold‑chain requirements), and import documentation.

Ipratropium bromide is an anticholinergic bronchodilator, whereas beta‑2 agonists such as albuterol act on adrenergic receptors to relax airway smooth muscle. Anticholinergics tend to have a slower onset but provide sustained bronchodilation and are often used as add‑on therapy. Long‑acting agents like tiotropium share a similar mechanism but have a longer duration of action.

Store the product at room temperature, preferably below 25 °C. Keep it in the original packaging to protect from moisture and light. Do not expose the inhalation device to extreme temperatures or humidity, and ensure the container is tightly closed when not in use.

The medication is delivered by inhalation, either through a nebulizer solution or a metered‑dose inhaler, as directed by the prescriber. The patient inhales the dose directly into the lungs, allowing the drug to act locally on airway smooth muscle.

Serious risks include urinary retention, especially in patients with prostate enlargement; exacerbation of narrow‑angle glaucoma leading to increased intra‑ocular pressure; severe allergic reactions such as anaphylaxis; and paradoxical bronchospasm, which requires immediate medical attention.

Patients with known hypersensitivity to ipratropium bromide or any formulation components should avoid the product. Individuals with narrow‑angle glaucoma, significant urinary retention, or severe prostate hypertrophy should not use it without close medical supervision. Contraindications must be evaluated by a qualified healthcare professional.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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