Product image of Ipratropiumbromid Teva (Ipratropium Bromide Monohydrate) supplied by GNH India

Ipratropiumbromid Teva

Active Ingredient:
Ipratropium Bromide Monohydrate
Origin:
EU

Ipratropiumbromid Teva (Ipratropium Bromide Monohydrate)

Ipratropium bromide, the active ingredient in Ipratropiumbromid Teva, is an anticholinergic (muscarinic antagonist) presented as an inhalation formulation for inhalation use. It provides bronchodilation to manage chronic obstructive pulmonary disease (COPD) and asthma in adult patients. By blocking muscarinic receptors in airway smooth muscle, it produces sustained airway opening and reduces mucus secretion.

GNH India supplies Ipratropiumbromid Teva as a licensed, GDP‑compliant international pharmaceutical supplier, providing reliable quality and regulatory compliance to hospitals, pharmacies and clinics worldwide, ensuring timely delivery and adherence to local import regulations.

Manufacturer / TM Owner

Teva B.V

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Indications & Clinical Uses

Ipratropium bromide is an anticholinergic bronchodilator that acts on the respiratory tract to improve airflow in obstructive airway diseases.

  • Chronic obstructive pulmonary disease (COPD): improves lung function, reduces dyspnea and exacerbations.
  • Asthma: provides maintenance bronchodilation and helps control symptoms.
  • Bronchospasm: delivers rapid airway relaxation to alleviate acute bronchoconstriction.
  • Exercise‑induced bronchoconstriction: reduces airway narrowing during physical activity.

How It Works

  • Ipratropium bromide exerts its effect by competitively antagonizing muscarinic (M3) receptors on airway smooth muscle. By blocking acetylcholine binding, it prevents intracellular calcium rise, leading to relaxation of bronchial smooth muscle and inhibition of mucus gland secretion, thereby producing bronchodilation and improved airway patency. The antagonism is localized to the respiratory tract due to limited systemic absorption, which minimizes systemic anticholinergic effects.

Side Effects

Ipratropium bromide may cause a range of adverse reactions, most of which are related to its anticholinergic activity in the respiratory tract.

Common Side Effects

  • Dry mouth.
  • Cough or throat irritation.
  • Headache.
  • Dizziness.
  • Nausea.
  • Taste alteration.

Serious or Rare Side Effects

  • Severe allergic reaction (anaphylaxis).
  • Paradoxical bronchospasm.
  • Urinary retention.
  • Exacerbation of narrow‑angle glaucoma.
  • Angioedema.
  • Tachycardia.

Precautions & Warnings

When prescribing ipratropium bromide, clinicians should consider several precautionary measures to ensure safe use.

  • Assess renal function: dose adjustment may be needed in severe renal impairment.
  • Monitor for anticholinergic effects: watch for dry mouth, constipation, urinary retention.
  • Caution in patients with narrow‑angle glaucoma: may exacerbate intraocular pressure.
  • Avoid use in patients with known hypersensitivity to ipratropium or formulation excipients.
  • Store at room temperature: keep in original container, protect from moisture and light.

Avoid Interactions

Ipratropium bromide can interact with other medications, altering its efficacy or increasing adverse effects.

Major Interactions (Avoid)

  • Concurrent use with other anticholinergic agents: increased anticholinergic burden.
  • Oral antihistamines with anticholinergic properties: additive dryness and urinary retention.

Moderate Interactions (Monitor Closely)

  • β2‑agonists: additive bronchodilation may increase risk of tachycardia.
  • Theophylline: may enhance bronchodilator effect.
  • Inhaled corticosteroids: monitor for combined respiratory effects.

Frequently Asked Questions

Ipratropiumbromid Teva is a prescription inhalation medication containing ipratropium bromide, an anticholinergic bronchodilator indicated for the maintenance treatment of chronic obstructive pulmonary disease (COPD) and asthma. It helps open the airways and reduce breathing difficulties associated with these conditions.

Ipratropium bromide works by competitively blocking muscarinic M3 receptors on airway smooth muscle. This inhibition prevents acetylcholine‑mediated contraction, leading to relaxation of bronchial muscles and reduced mucus secretion, which together improve airflow and ease breathing.

The dosage is individualized; the prescribing clinician determines the appropriate inhalation regimen based on the patient’s condition, severity, and response. No standard dose can be provided here, and patients should follow their healthcare provider’s instructions.

Safety data are limited. The medication should be used during pregnancy or lactation only if the potential benefit justifies any potential risk to the fetus or infant. Consultation with a qualified healthcare professional is essential before use in these situations.

Submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and necessary import documentation.

Compared with short‑acting β2‑agonists, ipratropium offers a longer duration of action and a different mechanism, making it useful as add‑on therapy. Unlike long‑acting anticholinergics, it is typically used for maintenance and occasional rescue, providing a favorable safety profile for patients who may experience β‑agonist side effects.

The product should be stored at room temperature, below 25 °C, in its original container, protected from moisture and direct sunlight. Keep the inhalation device sealed when not in use to maintain drug stability.

Ipratropium bromide is delivered via a metered‑dose inhaler or nebulizer solution. The patient inhales the prescribed number of puffs or nebulized dose, usually using a spacer or mouthpiece, following the healthcare provider’s instructions for technique and timing.

Serious adverse reactions, though uncommon, can include severe allergic responses such as anaphylaxis, paradoxical bronchospasm, urinary retention, and exacerbation of narrow‑angle glaucoma. Patients should seek immediate medical attention if they experience difficulty breathing, facial or throat swelling, or sudden vision changes.

Individuals with a known hypersensitivity to ipratropium bromide or any formulation excipients, as well as patients with uncontrolled narrow‑angle glaucoma or urinary retention, should avoid using this product. Clinicians must evaluate contraindications before prescribing.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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