Product image of Ipratropiumbromide 40 Cyclocaps Teva (Ipratropium Bromide) supplied by GNH India

Ipratropiumbromide 40 Cyclocaps Teva

Active Ingredient:
Ipratropium Bromide
Origin:
EU

Ipratropiumbromide 40 Cyclocaps Teva (Ipratropium Bromide)

Ipratropium Bromide, the active ingredient in Ipratropiumbromide 40 Cyclocaps Teva, is an anticholinergic (muscarinic antagonist) presented as a 40 µg inhalation capsule (Cyclocaps) for inhalation use. It treats chronic obstructive pulmonary disease and asthma by relaxing airway smooth muscle and reducing mucus secretion.

GNH India supplies Ipratropiumbromide 40 Cyclocaps Teva as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Teva B.V

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Indications & Clinical Uses

Ipratropium bromide acts on the muscarinic receptors of the respiratory tract to improve airflow in obstructive airway diseases.

  • Chronic obstructive pulmonary disease (COPD): improves lung function and reduces exacerbations.
  • Asthma: provides adjunct bronchodilation for maintenance therapy.
  • Bronchospasm (e.g., exercise‑induced): offers short‑acting relief of airway narrowing.

How It Works

  • Ipratropium bromide competitively blocks M3 muscarinic receptors on airway smooth muscle and submucosal glands, preventing acetylcholine‑mediated bronchoconstriction and decreasing mucus secretion, which results in bronchodilation and reduced airway resistance.

Side Effects

Ipratropium bromide may cause a range of adverse reactions, most of which are mild and reversible.

Common Side Effects

  • Dry mouth
  • Cough
  • Throat irritation
  • Headache
  • Dizziness
  • Altered taste perception

Serious or Rare Side Effects

  • Paradoxical bronchospasm
  • Severe allergic reaction (anaphylaxis)
  • Angioedema
  • Urinary retention
  • Increased intra‑ocular pressure
  • Cardiac arrhythmia

Precautions & Warnings

When prescribing Ipratropiumbromide 40 Cyclocaps, consider the following safety measures.

  • Assess respiratory status: evaluate baseline lung function before initiation.
  • Monitor anticholinergic effects: watch for dry mouth, urinary retention, or visual disturbances.
  • Use cautiously in narrow‑angle glaucoma: anticholinergic activity may worsen intra‑ocular pressure.
  • Avoid in patients with known hypersensitivity to ipratropium bromide or excipients.
  • Store at below 25°C: keep in the original pack, protect from moisture and direct sunlight.

Avoid Interactions

Ipratropium bromide has a low systemic absorption profile, yet certain drug combinations require attention.

Major Interactions (Avoid)

  • Concurrent use with other anticholinergic agents (e.g., tiotropium) may increase anticholinergic burden.
  • Co‑administration with ophthalmic anticholinergics can exacerbate intra‑ocular pressure.

Moderate Interactions (Monitor Closely)

  • Combined therapy with β2‑agonists may produce additive bronchodilation; monitor for tachycardia.
  • Use with antihistamines possessing anticholinergic properties may enhance dry‑mouth effects.
  • Caution when given with drugs that affect cholinergic pathways, such as atropine.

Frequently Asked Questions

Ipratropiumbromide 40 Cyclocaps Teva is a prescription inhalation capsule containing 40 µg of ipratropium bromide. It is indicated for the maintenance treatment of chronic obstructive pulmonary disease (COPD) and as an adjunct bronchodilator in asthma, helping to relax airway smooth muscle and reduce mucus production.

Ipratropium bromide is a competitive antagonist of muscarinic (M3) receptors on airway smooth muscle and submucosal glands. By blocking acetylcholine binding, it prevents bronchoconstriction and decreases secretions, leading to bronchodilation and improved airflow in the lungs.

The prescribed dose is determined by the treating physician based on the patient’s clinical condition, disease severity, and response to therapy. The prescriber selects the number of capsules per administration and the frequency, typically ranging from one to two inhalations several times daily.

Safety data in pregnancy and lactation are limited; the product is classified as pregnancy category unknown. It should be used only if the potential benefit justifies any potential risk to the fetus. Breastfeeding mothers should consult a healthcare professional before use.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

The primary alternative is the long‑acting muscarinic antagonist tiotropium, which offers once‑daily dosing and a longer duration of action. Ipratropium provides short‑acting relief, typically administered multiple times per day, and may be combined with β2‑agonists for additive bronchodilation. Choice depends on disease severity, dosing convenience and clinical response.

Store at below 25 °C in the original sealed packaging, protected from moisture and direct sunlight. Keep capsules in a dry place and avoid exposure to high humidity. Do not refrigerate or freeze. Follow any additional handling instructions provided by the supplier.

The capsule is placed into a compatible dry‑powder inhaler device, pierced, and the patient inhales the released powder through the mouthpiece with a steady, deep breath. Proper technique—including a full exhalation before inhalation and a brief breath‑hold after—maximizes drug delivery to the lungs.

Serious but rare adverse events include paradoxical bronchospasm, severe allergic reactions such as anaphylaxis, angioedema, and urinary retention or worsening glaucoma in susceptible individuals. Patients should seek immediate medical attention if they experience difficulty breathing, swelling of the face or throat, or visual disturbances.

Ipratropiumbromide 40 Cyclocaps should be avoided in patients with known hypersensitivity to ipratropium bromide or any excipients, and in individuals with narrow‑angle glaucoma or urinary retention where anticholinergic effects could exacerbate the condition. Contraindications should be confirmed by a healthcare professional before initiation.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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