Product image of Ipv-Boostrix (Aluminium Phosphate, Diphtheria Toxoid, Tetanus Toxoid, Pertussis Toxoid, Pertussis Filamentous Haem) supplied by GNH India

Ipv-Boostrix

Active Ingredient:
Aluminium Phosphate, Diphtheria Toxoid, Tetanus Toxoid, Pertussis Toxoid, Pertussis Filamentous Haem
Origin:
EU

Ipv-Boostrix (Aluminium Phosphate, Diphtheria Toxoid, Tetanus Toxoid, Pertussis Toxoid, Pertussis Filamentous Haem)

Diphtheria, tetanus, and acellular pertussis vaccine, the active ingredient in Ipv-Boostrix, is a vaccine presented as an injectable suspension for intramuscular use. It prevents diphtheria, tetanus and pertussis in children and adults and is included in routine immunisation schedules.

GNH India supplies Ipv-Boostrix as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide, ensuring reliable cold‑chain logistics and regulatory compliance.

Manufacturer / TM Owner

Glaxosmithkline Biologicals S.A.

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Indications & Clinical Uses

Ipv-Boostrix is a diphtheria, tetanus and acellular pertussis vaccine used in immunisation programmes to protect against these bacterial diseases.

  • Diphtheria: provides active immunity against diphtheria toxin.
  • Tetanus: provides active immunity against tetanus toxin.
  • Pertussis: provides active immunity against pertussis bacteria, including toxin and filamentous haemagglutinin.

How It Works

  • Ipv-Boostrix contains diphtheria, tetanus and pertussis toxoids together with filamentous haemagglutinin, adsorbed onto an aluminium phosphate adjuvant. After intramuscular injection the antigens are taken up by antigen‑presenting cells, stimulating B‑cell and T‑cell responses that generate high‑affinity antibodies and memory cells, thereby conferring protective immunity against the three pathogens.

Side Effects

Common and serious adverse reactions may occur after administration of Ipv-Boostrix.

Common Side Effects

  • Injection site pain, redness or swelling.
  • Low‑grade fever.
  • Headache.
  • Fatigue or malaise.
  • Mild muscle aches.

Serious or Rare Side Effects

  • Anaphylactic or severe allergic reaction.
  • Seizures or high‑grade fever.
  • Guillain‑Barré syndrome (very rare).

Precautions & Warnings

Before administering Ipv-Boostrix, consider the following safety measures.

  • Allergy to vaccine components: avoid if known hypersensitivity to any ingredient.
  • Acute moderate or severe illness: postpone vaccination until recovery.
  • Immunocompromised patients: evaluate risk‑benefit, response may be reduced.
  • Prior severe reaction to a dose: consult specialist before repeat dosing.
  • Pregnancy and lactation: safety not established; use only if benefit outweighs risk.
  • Store at 2-8°C: keep refrigerated, protect from light, do not freeze or shake.

Avoid Interactions

Vaccines can interact with other medicines or biologics; monitor the following.

Major Interactions (Avoid)

  • Concurrent live‑virus vaccines: postpone one of the vaccines by at least 4 weeks.
  • Immunoglobulin or blood products given within 48 hours: may diminish immune response.

Moderate Interactions (Monitor Closely)

  • Antipyretics (e.g., acetaminophen) taken prophylactically: may mask fever, but generally safe.
  • Other inactivated vaccines administered at the same visit: give at separate anatomical sites.
  • Immunosuppressive therapy: may reduce vaccine efficacy, consider timing of vaccination.

Frequently Asked Questions

Ipv-Boostrix is a combination vaccine that protects against diphtheria, tetanus and pertussis. It is administered as part of routine immunisation schedules for children and adults to establish active immunity against these bacterial diseases.

The vaccine contains inactivated toxoids of diphtheria and tetanus together with pertussis antigens, including filamentous haemagglutinin, adsorbed onto an aluminium phosphate adjuvant. After intramuscular injection, the immune system recognises these antigens, producing specific antibodies and memory cells that neutralise the toxins and prevent infection.

The dose and schedule of Ipv-Boostrix are determined by the prescribing healthcare professional based on age, immunisation history and local guidelines. The product is supplied as a single‑dose injectable suspension for intramuscular administration.

Safety data for Ipv-Boostrix in pregnancy and lactation are limited. It should only be used when the potential benefit to the mother outweighs any possible risk to the fetus or infant, and the decision should be made by a qualified healthcare provider.

To order Ipv-Boostrix, submit an enquiry on the product page at gnhindia.com specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, cold‑chain shipping details and the necessary import documentation.

Ipv-Boostrix is an acellular pertussis formulation that includes purified pertussis antigens and an aluminium phosphate adjuvant, offering a safety profile comparable to other modern DTaP vaccines. Compared with whole‑cell formulations, it typically causes fewer local and systemic reactions while providing similar protective efficacy.

Ipv-Boostrix must be stored refrigerated at 2 °C to 8 °C. Keep the vial in its original packaging, protect it from light, and avoid freezing or shaking. Do not use the product if it has been exposed to temperatures outside the recommended range.

The vaccine is supplied as a sterile injectable suspension. It is given by a single intramuscular injection, usually into the deltoid muscle of older children and adults or the anterolateral thigh of infants, following the dosing schedule recommended by health authorities.

Serious adverse events are rare but can include anaphylaxis, severe allergic reactions, high‑grade fever, seizures, and, very rarely, Guillain‑Barré syndrome. Immediate medical attention is required if signs of a severe reaction, such as difficulty breathing, swelling of the face or throat, or persistent high fever, occur after vaccination.

Individuals with a known severe allergy to any component of the vaccine, including aluminium phosphate or the specific toxoids, should not receive Ipv-Boostrix. Those who experienced a severe reaction after a previous dose of a DTaP vaccine should also avoid it unless evaluated by a specialist.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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