Product image of Irbesartan 1 A Pharma (Irbesartan) supplied by GNH India

Irbesartan 1 A Pharma

Active Ingredient:
Irbesartan
Origin:
EU

Irbesartan 1 A Pharma (Irbesartan)

Irbesartan, the active ingredient in Irbesartan 1 A Pharma, is an Angiotensin II receptor blocker (ARB) presented as an oral tablet for oral use. It is employed to manage high blood pressure and to protect kidney function in patients with diabetic kidney disease.

GNH India supplies Irbesartan 1 A Pharma as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide, adhering to EU quality standards and providing reliable global distribution.

Manufacturer / TM Owner

1 A Pharma Gmbh

1
Pack/s
This product is added to your enquiry list

Request a Quote

Please fill out the form below and our team will get back to you shortly with pricing and further information.

A minimum order value applies. Our team will confirm the exact amount or quantity after reviewing your requirements.

Indications & Clinical Uses

Irbesartan is used to treat conditions related to the renin‑angiotensin system, primarily hypertension and diabetic kidney disease.

  • Hypertension: lowers elevated blood pressure, reducing cardiovascular risk.
  • Diabetic nephropathy: slows progression of kidney damage in patients with type 2 diabetes.
  • Proteinuria in diabetes: reduces urinary protein excretion, indicating renal protection.

How It Works

  • Irbesartan selectively blocks angiotensin II type 1 (AT1) receptors on vascular smooth muscle and adrenal cells. By preventing angiotensin II binding, it inhibits vasoconstriction and aldosterone secretion, leading to vasodilation, reduced sodium and water retention, and ultimately lower blood pressure and decreased renal stress.

Side Effects

Irbesartan may cause a range of adverse reactions, varying from mild to serious.

Common Side Effects

  • Dizziness: sensation of light‑headedness, especially after standing.
  • Headache: mild to moderate pain in the head region.
  • Fatigue: feeling unusually tired or weak.
  • Upper respiratory tract infection: symptoms such as sore throat or nasal congestion.
  • Hyperkalaemia: modest increase in blood potassium levels.

Serious or Rare Side Effects

  • Angioedema: swelling of the face, lips, tongue or throat that may compromise breathing.
  • Acute renal failure: sudden decline in kidney function.
  • Severe hyperkalaemia: markedly elevated potassium that can affect heart rhythm.
  • Hepatic injury: signs of liver dysfunction such as jaundice or elevated enzymes.

Precautions & Warnings

When prescribing Irbesartan, clinicians should consider several safety measures.

  • Monitor blood pressure: ensure therapeutic reduction without excessive hypotension.
  • Assess renal function: check serum creatinine and eGFR before and during therapy.
  • Check serum potassium: especially in patients on potassium‑sparing agents.
  • Use caution in hepatic impairment: dose adjustment may be required.
  • Avoid in pregnancy: potential fetal toxicity.
  • Store at ambient temperature: keep in the original pack, protect from moisture and heat.

Avoid Interactions

Irbesartan can interact with other medicines, affecting its safety or effectiveness.

Major Interactions (Avoid)

  • Aliskiren (in diabetic patients): combined use may increase risk of renal impairment and hyperkalaemia.
  • Potassium‑sparing diuretics or potassium supplements: may cause dangerous hyperkalaemia.
  • ACE inhibitors: concurrent use raises the risk of renal dysfunction and elevated potassium.

Moderate Interactions (Monitor Closely)

  • NSAIDs: can blunt antihypertensive effect and affect renal function.
  • Lithium: levels may rise, leading to toxicity.
  • Thiazide diuretics: may enhance hypotensive response and affect electrolyte balance.

Frequently Asked Questions

Irbesartan 1 A Pharma is prescribed to lower high blood pressure (hypertension) and to slow the progression of kidney damage in patients with diabetic nephropathy. It may also be used to reduce proteinuria associated with diabetes, helping protect renal function.

Irbesartan blocks the angiotensin II type 1 (AT1) receptors, preventing angiotensin II from causing blood vessels to narrow and from stimulating aldosterone release. This results in vasodilation, reduced sodium and water retention, and lower blood pressure, while also decreasing stress on the kidneys.

The appropriate dose of Irbesartan 1 A Pharma is determined individually by a qualified prescriber based on the patient’s medical condition, response to therapy, and other medications. Patients should follow the dosing instructions provided by their healthcare professional.

Irbesartan is generally contraindicated during pregnancy because it may cause fetal harm. Safety during breastfeeding has not been established, so the drug should be used only if the potential benefit justifies the possible risk to the infant. Consultation with a healthcare provider is essential.

To place an order, submit an enquiry on the Irbesartan 1 A Pharma product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details, and any necessary import documentation.

Irbesartan belongs to the angiotensin II receptor blocker (ARB) class, offering similar blood‑pressure‑lowering efficacy to ACE inhibitors but with a lower incidence of cough. Compared with other ARBs, it has a comparable safety profile and is often chosen for patients who need renal protection in diabetic kidney disease.

Irbesartan 1 A Pharma should be stored at ambient temperature, below 25 °C. Keep the tablets in their original packaging, protect them from moisture, direct sunlight, and excessive heat to maintain potency throughout the shelf life.

Irbesartan 1 A Pharma is taken orally, usually once daily, with or without food. The tablet should be swallowed whole with a glass of water. Patients should not crush or chew the tablet unless specifically instructed by a healthcare professional.

The most serious risks include angioedema (swelling of the face, lips, tongue, or throat), severe hyperkalaemia (dangerously high potassium levels), and acute renal failure. Patients should seek immediate medical attention if they experience swelling, difficulty breathing, or sudden changes in kidney function.

Irbesartan should not be used by individuals with known hypersensitivity to the drug or any ARB, by pregnant women, or by patients with severe hepatic impairment. Caution is also advised for those with existing renal dysfunction or elevated potassium levels.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

Disclaimer

At GNH India, we aim to provide information that is expert-reviewed, accurate, and reliable. However, all content on this platform is intended for general informational purposes only and does not constitute professional medical advice, diagnosis, or treatment. While efforts are made to maintain accuracy and currency, the information may contain errors, omissions, or may not reflect the latest developments. Always consult a qualified healthcare professional regarding any medical concerns.

All product names, brand names, trademarks and registered trademarks displayed on this website are the property of their respective owners. This website and its operator are not affiliated with, endorsed by, or authorized by any such trade mark owners unless expressly stated. Any reference to product names or trademarks is made solely for descriptive and informational purposes. No commercial relationship, sponsorship, approval, or association with any trademark owner should be inferred. Information provided herein does not constitute promotion, advertising, or an offer for sale of any medicinal product and is intended solely for general informational purposes.

All trademarks and brand names displayed on this website are used strictly in accordance with the provisions of the Trade Marks Act, 1999, specifically Sections 30 and 30(1) governing fair use. Trademark ownership has been accurately attributed under the "Manufacturer/ TM Owner" section in compliance with statutory requirements.

Related Products

Other formulations containing Irbesartan

A

A
A

A
A

A
A

A

Browse all products →

Ordering Process

Simple, Secure, and Seamless

Learn how our streamlined ordering process guarantees fast, compliant, and reliable access to essential medicines worldwide.

Quote request form

01

Submit Quote Request Form

Tell us what medications you need by filling out our simple form and uploading a valid document.

Price estimate review

02

We Review & Send Estimate

Our licensed pharmacists will verify your details and provide you with a detailed cost estimate.

Secure payment

03

Confirm & Make Payment

Discuss any queries, approve the estimate, and complete your payment.

Worldwide delivery

04

Get Delivered

Your medicines, safely packed and delivered to your door or nearest airport — hassle-free.

Regulatory recognitions

Quality You Can Trust

Our internationally recognized certifications underscore our commitment to safety, quality, and excellence.

SGS GSDP Certification

GSDP Compliant from SGS

URS ISO 9001

URS ISO 9001 Certification

FDA Maharashtra

Licensed by FDA Maharashtra

IEC License DGFT

IEC License issued by DGFT